Chronic Obstructive Pulmonary Diseases and Proprioceptive Neuromuscular Facilitation

The Effect of Resistant Proprioceptive Neuromuscular Facilitation Exercises on Respiratory Muscle Strength in Chronic Obstructive Pulmonary Diseases

To investigate the effects of resistant proprioceptive neuromuscular facilitation exercises on physical fitness, respiratory muscle strength, walking distance and quality of life in chronic obstructive pulmonary patients.

Study Overview

• Status: Completed
• Conditions: Chronic Obstructive Pulmonary Disease
• Intervention / Treatment: Diagnostic test: MIP/MEP

Detailed Description

The study was carried out between January 2017 and January 2019, with patients followed up with the diagnosis of COPD in Çanakkale Mehmet Akif Ersoy State Hospital and Çanakkale Onsekiz Mart University Medical Faculty Hospital, Department of Chest Diseases. It was approved by Istanbul Medipol University Non-Interventional Clinical Research Ethics Committee (Date: 30.12.2016, Decision No. 573) and was done in accordance with the Declaration of Helsinki. All participants were informed about the purpose of the study, the total duration of treatment and the applications to be made, and a consent form was signed. The study was conducted as a prospective and randomized controlled study, and inclusion and exclusion criteria were determined.

Thirty-five patients diagnosed with COPD were referred to the study, four patients were excluded because they did not meet the inclusion criteria, and the study was conducted with a total of 31 participants.

The 31 patients included in the study were randomized after their initial evaluation and divided into two groups as experimental and control groups. Patients meeting the inclusion criteria were divided into 2 groups. Randomized by ordering by date of application.

• Study Type: Interventional
• Enrollment (Actual): 31
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Turkey
  • Çanakkale, Turkey, 17100
    • Mehmet Akif Ersoy State Hospital
  • Çanakkale, Turkey, 17100
    • Canakkale Onsekiz Mart University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 38 years to 67 years (ADULT, OLDER_ADULT)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• To be diagnosed with stage 1, stage 2 and stage 3 COPD according to GOLD (Global Initiative for Obstructive Lung Diseases) criteria
• Having FEV1/FVC <70% according to pulmonary function test
• Being clinically stable
• Being over 18 years old
• Volunteer to participate in the program

Exclusion Criteria:

• Having a COPD exacerbation in the last 8 weeks
• To have participated in a regular exercise training program in the last 1 year
• Having a musculoskeletal disease and neuromuscular disease that may prevent exercise
• Inability to cooperate for pulmonary function test and respiratory muscle strength measurement
• Being on long-term oxygen therapy

Study Plan

How is the study designed?

Design Details

• Primary Purpose: TREATMENT
• Allocation: RANDOMIZED
• Interventional Model: PARALLEL
• Masking: SINGLE

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
EXPERIMENTAL: Maximal Inspiratory Pressure; MIP Maximal Inspiratory Pressure	Diagnostic test: MIP/MEP; MIP/MEP
EXPERIMENTAL: Maximal Expiratory Pressure; MEP Maximal Expiratory Pressure	Diagnostic test: MIP/MEP; MIP/MEP

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
HADS	Hospital Anxiety Depression Scale	10 minutes

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
SGRQ	St George's Respiratory Questionnaire	15 minutes

Collaborators and Investigators

• Sponsor: Istanbul Medipol University Hospital
• Collaborators: Çanakkale Onsekiz Mart University; Mehmet Akif Ersoy Canakkale State Hospital

Study record dates

Study Major Dates

• Study Start (ACTUAL): January 20, 2017
• Primary Completion (ACTUAL): March 17, 2019
• Study Completion (ACTUAL): December 1, 2022

Study Registration Dates

• First Submitted: February 3, 2023
• First Submitted That Met QC Criteria: February 3, 2023
• First Posted (ACTUAL): February 10, 2023

Study Record Updates

• Last Update Posted (ACTUAL): February 10, 2023
• Last Update Submitted That Met QC Criteria: February 3, 2023
• Last Verified: February 1, 2023

More Information

Terms related to this study

• Keywords: COPD
• Additional Relevant MeSH Terms: Respiratory Tract Diseases; Lung Diseases; Lung Diseases, Obstructive; Pulmonary Disease, Chronic Obstructive
• Other Study ID Numbers: IstanbulMUH_1999

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No