Effects of Concurrent Training on Physical Fitness and Body Composition in Obese Individuals (CONCOB)

August 19, 2025 updated by: Istituto Auxologico Italiano

Effects of a Concurrent Home-based Training on Cardiorespiratory Fitness, Muscular Strength, Balance, Daily-life Activities and Body Composition in Obese Individuals

Ample evidence demonstrates the beneficial role of physical activity combined with a structured dietary plan to counteract obesity. International guidelines as the World Health Organization states that to improve fitness levels at least 150 min a week of physical activity at moderate intensity, combined with resistance training composed of 8-12 repetitions with an intensity of 60-70%1RM for each muscle group, are recommended. In this regard, a minimum dosage of 60-90 min of physical activity composed by aerobic exercises in alternation with resistance training protocols, allow a sequential development of cardiorespiratory fitness and muscular strength parameters avoiding potential interference effects. Interference may occur when strength and endurance stimuli both target opposite peripheral adaptations (e.g., hypertrophy vs. muscle capillarization) and this phenomenon seems to be particularly clear during adolescence. Nevertheless, the incorporation of different training stimuli within the same training session is called Concurrent Training. This training mode, thanks to the activation of two different metabolic pathways (e.g., aerobic and anaerobic), has a variety, beneficial effects in terms of muscle mass and strength development, body composition profile regulation and neuromotor function improvement. Concurrent Training seems to be effective not only in normal-weight subjects, but also in obese individuals, reporting positive adaptations on physical fitness and health status compared with a single-mode (i.e., aerobic or strength training). Therefore, the aim of this study is to detect the effects of a 10-week-Concurrent Training protocol compared with a single training modality on physical fitness, body composition and circadian rhythms in adult outpatients with obesity.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

132

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Italy
      • Milan, Italy, 20145
        • Istituto Auxologico Italiano IRCCS

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

25 years to 60 years (Adult)

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Physical activity frequency minor of 2 days/week
  • BMI major of 30 kg/m2
  • informed consent signature

Exclusion Criteria:

  • age over 65 years
  • knee or hip pain (visual analogue scale score >7 arbitrary units
  • a history of hip, knee or foot replacement or osteoarthrosis
  • cardiac infarction
  • neurological impairments or any other clinical condition that affects the practice of physical activity

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Basic Science
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Concurrent Training
Experimental: home-based concurrent training composed by strength and aerobic exercises within the same training session
Other: Concurrent Training
Participants should perform strength training and aerobic exercises
Experimental: Strength Training
Experimental: home-based resistance training mode
Other: Strength Training
Participants should perform strength exercises
Experimental: Aerobic Training
Experimental: home-based endurance training mode
Other: Aerobic training
Participants should perform aerobic exercises

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Change from baseline strength in kilograms at 10 weeks
Time Frame: Up to 10 weeks
Maximum isometric handgrip strength using a dynamometer
Up to 10 weeks
Change from baseline cardiorespiratory fitness in number of steps performed at 10 weeks fitness
Time Frame: Up to 10 weeks
Maximum aerobic capacity using the two minute step test
Up to 10 weeks
Change from baseline postural control in arbitrary units at 10 weeks
Time Frame: Up to 10 weeks
Balance and postural control using the Balance Error Scoring System
Up to 10 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Change from baseline fat mass percentage at 10 weeks
Time Frame: Up to 10 weeks
Fat mass % using a Tetrapolar Bioelectrical Impedance
Up to 10 weeks
Change from baseline weight in kilograms at 10 weeks
Time Frame: Up to 10 weeks
weight status using weight scale
Up to 10 weeks
Change from baseline height in meters at 10 weeks
Time Frame: Up to 10 weeks
height using a stadiometer
Up to 10 weeks
Change from baseline waist circumference in centimeters at 10 weeks
Time Frame: Up to 10 weeks
waist circumference using a 200 cm tape
Up to 10 weeks
Change from baseline circadian rhythm in arbitrary units at 10 weeks
Time Frame: Up to 10 weeks
Chronotype profile using Morningness-Eveningness Questionnaire
Up to 10 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Istituto Auxologico Italiano

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

Helpful Links

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

October 1, 2022

Primary Completion (Actual)

February 28, 2023

Study Completion (Actual)

April 30, 2024

Study Registration Dates

First Submitted

February 20, 2023

First Submitted That Met QC Criteria

March 3, 2023

First Posted (Actual)

March 14, 2023

Study Record Updates

Last Update Posted (Actual)

August 21, 2025

Last Update Submitted That Met QC Criteria

August 19, 2025

Last Verified

August 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 43C202

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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