Effects of COP Exercise and HIIT on Vascular Health in Young Overweight Females

April 5, 2023 updated by: Beijing Sport University

Effects of Crossover Point Exercise and High-intensity Interval Training on Vascular Health in Young Overweight Females

The goal of this study is to determine the effects of high-intensity interval training and crossover point exercise training on vascular health in young overweight women.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

In recent years, improving cardiovascular health through exercise has become a popular research question, however, it is not clear which intensity and modes of exercise bring more benefits. Crossover point(COP) intensity has great medical potential as a personalized exercise intensity that is based on substrate utilization mode, especially in overweight and obese people.On the other hand, several studies have demonstrated that HIIT is an effective method in improving vascular endothelial dysfunction. During our study, we evaluated the vascular health changes in young overweight women who received either COP exercise or HIIT exercise for 10 weeks.

Study Type

Interventional

Enrollment (Actual)

20

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • China
      • Beijing, China
        • Beijing Sport University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  1. Female, 18-30 years old
  2. Body mass index (BMI) < 28 kg/m2 and ≥ 24 kg/m2
  3. No exercise habit, and no recent new exercise plan
  4. No contraindications to exercise

Exclusion Criteria:

  1. Participates had an orthopedic or other condition that limited participation in daily exercise
  2. Participates had a history of myocardial infarction, stroke, diabetes mellitus, chronic respiratory disease or cancer
  3. Participates had smoking or alcohol behavior

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Prevention
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: HIIT group
Behavioral: high-intensity interval training (HIIT)
Participants in both the COP and HIIT groups underwent 30 sessions of exercise performed over 10 weeks. The training sessions in the HIIT group involved five high-intensity intervals of 4 minutes each (running or walking on a treadmill) at 85% VO2max interspersed with 3 minutes of low-intensity walking.
Experimental: COP group
Behavioral: crossover point(COP) exercise training
Participants in both the COP and HIIT groups underwent 30 sessions of exercise performed over 10 weeks. The COP exercise training sessions involved 45 minutes of continuous exercise at the COP on a treadmill.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
brachial-ankle pulse wave velocity (baPWV)
Time Frame: 10 weeks
The change of baPWV before and after intervention
10 weeks
blood pressure
Time Frame: 10 weeks
The change of blood pressure before and after intervention
10 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Interleukin 6 (IL-6)
Time Frame: 10 weeks
The change of IL-6 level before and after intervention
10 weeks
Homocysteine (HCY)
Time Frame: 10 weeks
The change of HCY level before and after intervention
10 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Beijing Sport University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

February 18, 2019

Primary Completion (Actual)

July 5, 2019

Study Completion (Actual)

October 25, 2019

Study Registration Dates

First Submitted

April 5, 2023

First Submitted That Met QC Criteria

April 5, 2023

First Posted (Actual)

April 18, 2023

Study Record Updates

Last Update Posted (Actual)

April 18, 2023

Last Update Submitted That Met QC Criteria

April 5, 2023

Last Verified

April 1, 2023

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • EOCPEAHITOVHIYOF

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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