Incidence of Descemet Membrane Detachment Post GATT by AS OCT

March 13, 2024 updated by: Marwa Elsayed Soliman Ahmed, Cairo University

Incidence of Descemet Membrane Detachment Post Gonioscopy-Assisted Transluminal Trabeculotomy by Anterior Segment Optical Coherence Tomography in Patients With Open Angle Glaucoma

detection of Incidence of Descemet membrane detachment post gonioscopy-assisted transluminal trabeculotomy by anterior segment optical coherence tomography in patients with open angle glaucoma.

Study Overview

Status

Active, not recruiting

Conditions

Intervention / Treatment

Detailed Description

In our study, which should include 30 eyes with OAG who underwent 360 GATT Screening for Descemet Membrane Detachment will be done by Anterior Segment Optical coherence Tomography using SD-OCT: Optovue RTVue (Optovue Inc., Fremont, CA, USA) for the angle day 1 post operative for all patients and 1 week post operative in cases with Descemet membrane detachment to check for spontaneous resolution.

One month post-operative the patients underwent

  • Best corrected visual acuity (BCVA) using decimal.
  • IOP measurement using GAT.

Study Type

Interventional

Enrollment (Actual)

30

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
    • Almanial
      • Cairo, Almanial, Egypt
        • Facility of medicine , Cairo University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  1. Age 18 - 70 years.
  2. Patients with open angle glaucoma undergoing gonioscopy assisted transluminal trabeculotomy.

Exclusion Criteria:

  1. Patients with with open angle glaucoma and aphakia.
  2. Patients with Congenital Glaucoma.
  3. Patients with open angle glaucoma undergoing phaco -gonioscopy-assisted transluminal trabeculotomy.
  4. Patients with neovascular glaucoma.
  5. Patients with pigmentary Glaucoma.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Diagnostic
  • Allocation: N/A
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: GATT group
detection of incidence of Descemet membrane detachment post gonioscopy-assisted transluminal trabeculotomy by anterior segment optical coherence tomography in patients with open angle glaucoma.
Procedure: Gonioscopy-Assisted Transluminal Trabeculotomy
Ab interno angle surgery one of MIGS to lower IOP

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Incidence of Descemet Membrane detachment post GATT
Time Frame: 4 months
Incidence of Descemet membrane Detachment post Gonioscopy-Assisted Transluminal Trabeculotomy
4 months

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Amount of reduction of IOP and Glaucoma NGM
Time Frame: 4 months
Amount of reduction of intraocular pressure and Number of Glaucoma medications
4 months
Incidence of Hyphema post GATT
Time Frame: 4 months
Incidence of Hyphema post Gonioscopy-Assisted Transluminal Trabeculotomy
4 months
Incidence of Descemet membrane detachment post gonioscopy-assisted transluminal trabeculotomy by anterior segment optical coherence tomography in patients with open angle glaucoma.
Time Frame: 4 months
Incidence of Descemet membrane detachment post gonioscopy-assisted transluminal trabeculotomy by anterior segment optical coherence tomography in patients with open angle glaucoma.
4 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Cairo University

Investigators

  • Principal Investigator: Fayrouz Aboalazayem, phD, Cairo university

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

December 1, 2022

Primary Completion (Actual)

March 1, 2024

Study Completion (Estimated)

May 10, 2024

Study Registration Dates

First Submitted

May 7, 2023

First Submitted That Met QC Criteria

July 3, 2023

First Posted (Actual)

July 6, 2023

Study Record Updates

Last Update Posted (Actual)

March 15, 2024

Last Update Submitted That Met QC Criteria

March 13, 2024

Last Verified

March 1, 2024

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • MS-275-2022

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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