Feasibility Study of Peripheral Venous Cannulation Pain in Predicting Acute Pain After Total Knee Arthroplasty

Feasibility Study of Peripheral Venous Cannulation Pain in Predicting Acute Pain After

The goal of this prospective observational study is to explore the feasibility of preoperative peripheral venous cannulation pain score in predicting acute pain after total knee arthroplasty, including resting pain and movement-evoked pain.

Study Overview

• Status: Not yet recruiting
• Conditions: Acute Pain; Total Knee Arthroplasty; Venous Cannulation Pain; Movement-evoked Pain
• Intervention / Treatment: Other

• Study Type: Observational
• Enrollment (Estimated): 180

Contacts and Locations

• Study Contact: Name: Liqin Tao; Phone Number: 18020264650; Email: 1349468702@qq.com

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: Yes

• Sampling Method: Non-Probability Sample

Study Population

Patients undergoing unilateral total knee arthroplasty for the first time under general anesthesia combined with nerve block

Description

Inclusion Criteria:

1. Patients undergoing the first unilateral total knee arthroplasty surgery under general anesthesia combined with nerve block ;
2. Age : 18 years old ≤ age ≤ 80 years old ;
3. ASA grade I-II ;
4. Informed consent was signed by patients or immediate family members before operation.

Exclusion Criteria:

1. There are known pain abnormalities, mental disorders, cognitive dysfunction ;
2. patients with long-term use of opioids and a history of drug dependence ;
3. patients with alcohol dependence ;
4. the patient refused to use the analgesic pump ;
5. Difficult to understand the VAS score ;
6. body mass index ≥ 40 ;
7. hand nerve abnormalities, hand loss ;
8. plan postoperative ICU patients ;
9. In other cases, the researchers believe that is not suitable for this researcher.

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
postoperative resting pain and movement-evoked pain	visual analogue scale（VAS) of one hour、the first day and the second day after operation	one hour、the first day and the second day after operation

Collaborators and Investigators

• Sponsor: RenJi Hospital

Study record dates

Study Major Dates

• Study Start (Estimated): August 30, 2023
• Primary Completion (Estimated): August 30, 2024
• Study Completion (Estimated): August 30, 2024

Study Registration Dates

• First Submitted: August 16, 2023
• First Submitted That Met QC Criteria: August 16, 2023
• First Posted (Actual): August 21, 2023

Study Record Updates

• Last Update Posted (Actual): September 7, 2023
• Last Update Submitted That Met QC Criteria: September 5, 2023
• Last Verified: September 1, 2023

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Pain; Neurologic Manifestations; Acute Pain
• Other Study ID Numbers: taoliqin0730

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No