Chlorhexidine Gluconate Bathing Education Video Among Hospitalized Patients

Chlorhexidine Gluconate Bathing Education Video Intervention Among Hospitalized Patients: A Pragmatic Cluster Randomized Clinical Trial

Chlorhexidine gluconate (CHG) bathing is an effective intervention to reduce hospitalized patient's risk of acquiring a central line-associated bloodstream infection (CLABSI). While daily CHG bathing for hospitalized patients is widely supported in the literature, patient adherence with this practice is suboptimal. Written and verbal information is provided to patients by nursing staff regarding the importance of CHG bathing and the correct usage of the CHG cloths; however, these methods can be hindered by literacy and language barriers. Medical videos have become popular avenues to provide necessary education to patients, and have been shown to improve patient-reported outcomes. Whereas the benefits of educational videos has been described in previous studies on advanced care planning and postoperative quality of life, they have not been described for CHG bathing. In this study, we aim to provide education (including the rationale/importance of CHG bathing, and the appropriate process for bathing) through the use of a short video provided to hospitalized patients. The purpose of this study is to evaluate the use of medical videos to educate patients on CHG bathing while hospitalized in the inpatient setting.

Study Overview

• Status: Completed
• Conditions: Infections
• Intervention / Treatment: Behavioral: CHG Skin Treatment Video

Detailed Description

For this study, approximately 16 inpatient units will be included; 8 will be randomized to the intervention (access to patient-facing CHG video) with the remaining units continuing with usual care (providing education via verbal/written information). All patients who require a CHG bath would be eligible to participate.

Intervention Group: In addition to the current educational document available for CHG bathing, patients admitted to the intervention units will be provided access to a CHG bathing video through multiple avenues (QR codes placed in the room/unit, video provided on unit iPads). Nurses will be instructed to provide QR codes to patients to scan and watch the video. Patients can scan the QR code using their own smart device or through unit-based iPads. After viewing the video, patients will be directed to scan a separate QR code to complete a voluntary questionnaire.

Control Group: Patients in the control group would have access to the current education available (patient education document) - usual care

• Study Type: Interventional
• Enrollment (Actual): 1000
• Phase: Not Applicable

Contacts and Locations

Study Locations

• United States
  • North Carolina
    • Durham, North Carolina, United States, 27710
      • Duke University Hospital
    • Raleigh, North Carolina, United States, 27610
      • WakeMed Health and Hospitals

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• Patients admitted to an intervention unit who require a CHG skin treatment

Exclusion Criteria:

• CHG allergy
• Patients on comfort care

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Health Services Research
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Intervention Group; Intervention Group: In addition to the current educational document available for CHG bathing, patients in the intervention group would be provided access to a CHG bathing video through multiple avenues (QR codes placed in the room/unit, video provided on unit iPads). Nurses will be instructed to provide QR codes to patients to scan and watch the video. Patients can scan the QR code using their own smart device or through unit-based iPads. After viewing the video, there is another QR code to scan that goes to a short patient survey.	Behavioral: CHG Skin Treatment Video; Short CHG skin treatment video that reviews the rationale/importance of CHG bathing, and the appropriate process for bathing
No Intervention: Control Group; Control Group: Patients in the control group would have access to the current education available (patient education document) - usual care

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Percentage of patients with a documented chlorhexidine gluconate bath documentation compliance	Compliance with documenting CHG bath treatment in the electronic health record; measured via a report from the electronic health record	Up to 12 months

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Patient-centered outcome questionnaire	Patients' perceptions of: how helpful they found the video; if they are likely to participate in CHG skin treatments; how comfortable they were watching the video	4 weeks
Rate of central line associated bloodstream infections per 1000 central line days	Central line associated bloodstream infection rate per 1000 patient days, measured by standard National Healthcare Safety Network (NHSN) criteria by the hospital's infection prevention departments	Up to 12 months
Patient use of CHG skin treatment video	number of patients who opened the video, percentage of patients who opened the video (# of video views / total # of patients admitted to the unit per month), percentage of the video viewed	4 weeks

Collaborators and Investigators

• Sponsor: Duke University
• Collaborators: Massachusetts General Hospital; Indiana University Health

Study record dates

Study Major Dates

• Study Start (Actual): May 1, 2024
• Primary Completion (Actual): September 30, 2025
• Study Completion (Actual): September 30, 2025

Study Registration Dates

• First Submitted: October 10, 2023
• First Submitted That Met QC Criteria: October 27, 2023
• First Posted (Actual): November 1, 2023

Study Record Updates

• Last Update Posted (Estimated): October 15, 2025
• Last Update Submitted That Met QC Criteria: October 13, 2025
• Last Verified: October 1, 2025

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Infections
• Other Study ID Numbers: Pro00112033

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No