Motor Relearning Program and Aerobic Exercise in Postural Stability and Lower Limb Function in Subacute Stroke Patients

June 24, 2024 updated by: Riphah International University

Combined Effects of Motor Relearning Program and Aerobic Exercise in Postural Stability and Lower Limb Function in Subacute Stroke Patients

The aim of the study is to determine combined effects of MRP and aerobic exercise in postural stability and lower limb function in subacute stroke patients

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Detailed Description

A study was done in 2023 on the treatment effects of low frequency repetitive Trans cranial magnetic stimulation combined with motor relearning program on spasticity and limb motor function in stroke patients. Stroke patients were randomly assigned into a control group and a combined treatment group. The Fugl Meyer scale, the Motor Evoked Potential test, and the Modified Ashworth scale were the instruments utilized. They came to the conclusion that low frequency rTMS plus MRP was more effective than MRP alone at improving spasticity and motor function in stroke patients with hemiparesis.

A study was done in 2023 on the effect of motor relearning program with obstacle walking on dynamic gait performance and functional mobility in sub-acute stroke subjects in India.Group B underwent a 30-minute obstacle walking program in addition to Group A's motor relearning program. Group comparison of the DGI and MAS pre- and post-test results revealed statistically significant differences in both groups. In order to improve dynamic gait performance and functional mobility in sub-acute stroke patients, they found that while both interventions were effective on their own, the motor relearning program in conjunction with obstacle walking was superior to the motor relearning program used alone.

A study was done on effects of the home-based exercise program with an augmented reality system on balance in patients with stroke; a randomized controlled trial in 2022. 68 stroke patients were enrolled in this study under the supervision of a blind observer. The written and visual HEP was administered to patients in the smart rehabilitation group. They came to the conclusion that the smart-rehabilitation group had a greater change in balance than the control group.

A study was done in 2019 on the impact of proprioceptive neuromuscular facilitation and motor relearning on improving functional mobility in individuals with sub-acute stroke. The goal of the research was to determine whether proprioceptive neuromuscular facilitation and motor relearning could improve functional mobility in patients with sub-acute strokes. There were thirty subjects, aged 45-55, who were in stages 3 and 4 of Brunnstrom recovery after having a stroke. They concluded that compared to subjects treated with proprioceptive neuromuscular facilitation alone, those treated with a motor relearning program and proprioceptive neuromuscular facilitation showed improvements in functional mobility.

In another study which was done in 2018 on the topic aerobic with resistance training or aerobic training alone post stroke: A secondary analysis from a RCT. They investigated the effects of AT+RT versus AT on psychological outcomes in chronic stroke with motor impairments. They concluded AT+RT versus AT yielded similar significant improvement.

Many studies have determined the effects of motor relearning program and proprioceptive neuromuscular facilitation on functional mobility and balance but according to the researcher's knowledge there is no evidence of effects of motor relearning program on postural stability. Moreover, the effects of aerobic exercise on cardiovascular fitness and upper limb function have strong evidence but little research has been done on the effects of aerobic exercise on lower limb in stroke patients. The literature gap between studies on effects of aerobic exercise and motor relearning program is wide. The aim of this study is to bridge this gap by providing evidence-based recommendations and optimizing exercise strategies tailored to the unique needs of the sub-acute stroke patients.

Study Type

Interventional

Enrollment (Estimated)

44

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • Pakistan
    • Punjab
      • Sialkot, Punjab, Pakistan, 51040
        • Recruiting
        • Islam Central Hospital , New life hospital
        • Contact:
        • Principal Investigator:
          • Maham Nasir, Dpt
        • Sub-Investigator:
          • Hira Jabeen, MsNmpt

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • • Both male and female patients were included.

    • Stroke patients with age range 50-70 years
    • Stroke patients with no serious unstable medical complications.
    • Patients with ischemic stroke
    • Patients who can follow directions (written, verbal, demonstration)
    • Patients who were not receiving any other form of physiotherapy treatment.
    • Patients with cognition level of >24 on MMSE scale
    • Stroke patients with 1 to 5 months of stroke history (Sub-Acute Stroke Patients)

Exclusion Criteria :

  • • Patients with any cardiac problem

    • Patients with history of any other neurological disease other than stroke.
    • Patients with peripheral arterial occlusive disease
    • Patients with surgeries like amputations of lower limb
    • MAS score > +3 were not included

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Combined MRP and aerobic exercise
Group A received MRP treatment and aerobic exercise along with conventional therapy
Other: Motor Relearning Program(MRP) and aerobic exercise
Participants of this group received training for a total of 8 weeks in the form of 3 sessions per week each session of 40 minutes, with a total of 24 sessions.
Experimental: MRP group
Group B received MRP treatment along with conventional therapy
Other: Motor Relearning Program(MRP)
the week 8 session was held in which patients were involved in 60-minute activities that involved practicing functional tasks without explicitly giving any type of relationship between those learned skills and the remedial tasks.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Postural assessment scale for e
Time Frame: 8th week
The postural assessment scale for stroke is an outcome measure specifically designed to assess and monitor postural control after stroke.The PASS consists of a 4-point scale where items are scored from 0 - 3. The total score ranges from 0 - 36.The higher the score is, the more favourable the balance in stroke patients.
8th week
Lower extremity functional scale
Time Frame: 8th week
LEF is a questionnaire containing 20 questions about a person's ability to perform everyday tasks. LEFS is scored on a scale of 0 to 80, with higher scores indicating better lower limb function. The interpretation of the scores can be based on the following categories: 0-20: Severe functional limitation. 21-40: Moderate functional limitation.
8th week

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Riphah International University

Investigators

  • Principal Investigator: Aruba Saeed, PhD, Riphah International University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

February 1, 2024

Primary Completion (Estimated)

July 30, 2024

Study Completion (Estimated)

July 30, 2024

Study Registration Dates

First Submitted

June 11, 2024

First Submitted That Met QC Criteria

June 24, 2024

First Posted (Actual)

June 26, 2024

Study Record Updates

Last Update Posted (Actual)

June 26, 2024

Last Update Submitted That Met QC Criteria

June 24, 2024

Last Verified

June 1, 2024

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • REC/RCR&AHS/23/02102

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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