Effects of an Exercise Program on Reaction Time and Mouse Accuracy in Recreational Video Game Players

This study is intended to evaluate the effects of an exercise program on the change of electronic sports (esports) athletes' reaction time and mouse click accuracy. The benefits of participation are directly related to exercise, and include improved thinking, performance, sleep, and quality of life.

Study Overview

• Status: Recruiting
• Conditions: Quality of Life
• Intervention / Treatment: Other: Resistance combined with cardiovascular training

• Study Type: Interventional
• Enrollment (Estimated): 15
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Timothy Tiu, MD; Phone Number: 305.243.3140; Email: ttiu@miami.edu

Study Locations

• United States
  • Florida
    • Miami, Florida, United States, 33146
      • Recruiting
      • University of Miami
      • Principal Investigator: Timothy Tiu, MD
      • Contact: Timothy Tiu, MD; Phone Number: 305.243.3140; Email: ttiu@miami.edu

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion criteria:

1. Minimum age is 18, and there is no maximum.
2. Must play video games for at least an average of one hour per week
3. University of Miami College student or University of Miami Miller School of Medicine student

Exclusion criteria:

1. Individuals who are not able to participate in a full body exercise program, whether due to injury or an underlying medical condition
2. Individuals who cannot comprehend basic instruction on exercise whether due to a cognitive impairment or language barrier (ie: non English speaker).
3. Conditions that require further medical workup including History or symptoms of cardiac disease, family history of sudden cardiac death, sickle cell disease, history of exercise-related syncope, uncontrolled exercise-associated asthma, acute fractures, active infectious rash, symptoms of relative energy deficiency syndrome, eating disorders.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Other
• Allocation: N/A
• Interventional Model: Single Group Assignment
• Masking: None (Open Label)

Number of Arms

1

Arms and Interventions

Participant Group / Arm

Intervention / Treatment

Experimental: Resistance combined with cardiovascular training group; Participants in this group will receive the resistance combined with cardiovascular training intervention for up to 6 weeks

Other: Resistance combined with cardiovascular training; Participants will undergo a 6-week exercise program designed under the supervision of a board certified sports medicine physician. The exercise program will consist of a 3 day per week schedule: Monday will be lower body resistance training, Wednesday will be aerobic exercise, and Friday will be upper body resistance training. Each session will be approximately up to 1 hour.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Change in participants' physical reaction time	Participants' reaction time will be measured in milliseconds using open-source software "Open-source open-access reaction time test"	Baseline and up to 6 weeks after starting the program
Change in percentage of participants' mouse click accuracy	Participants' mouse click accuracy will be measured as a percentage using a web-based program, "Mouse Accuracy"	Baseline and up to 6 weeks after starting the program

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Change in participants' number of target efficiency	Change in participants' number of target efficiency will be calculated as number of hits divided by possible targets using "Mouse Accuracy"	Baseline and up to 6 weeks after starting the program
Change in participants' clicks per second	Change in participants' clicks per second will be measured by counting actual mouse clicks per second using "Mouse Accuracy"	Baseline and up to 6 weeks after starting the program

Collaborators and Investigators

• Sponsor: University of Miami
• Investigators: Principal Investigator: Timothy Tiu, MD, University of Miami

Study record dates

Study Major Dates

• Study Start (Actual): October 17, 2025
• Primary Completion (Estimated): July 1, 2026
• Study Completion (Estimated): July 1, 2026

Study Registration Dates

• First Submitted: July 16, 2024
• First Submitted That Met QC Criteria: July 16, 2024
• First Posted (Actual): July 22, 2024

Study Record Updates

• Last Update Posted (Estimated): October 21, 2025
• Last Update Submitted That Met QC Criteria: October 17, 2025
• Last Verified: October 1, 2025

More Information

Terms related to this study

• Keywords: Exercise
• Additional Relevant MeSH Terms: Behavior; Motor Activity
• Other Study ID Numbers: 20250409

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No