The Impact of Exercise Methods on Human Body Functions and Metabolism (EXMET-BW&Y)

Comparative Study on the Effects of Brisk Walking and Yoga on Glucose and Lipid Metabolism and Neurocognitive Function in Adults: A Randomized Controlled Trial

The objective of this study is to compare the effects of 8 months of yoga and walking exercise training on weight-related body fat and metabolic biomarkers in women. Participants will be randomly assigned to either a yoga group or a walking group. The yoga group will undergo 90-minute sessions, 3 times per week, while the walking group will engage in one-hour sessions, 6 times per week. Physical and metabolic markers will be measured at baseline and after 8 months of intervention.

Study Overview

• Status: Recruiting
• Conditions: Metabolic Syndrome
• Intervention / Treatment: Behavioral: Yoga; Behavioral: Brisk walking

Detailed Description

This randomized controlled trial aims to investigate the differential impacts of yoga and walking exercise training on weight-related body fat and metabolic biomarkers in women over an 8-month period. The study will recruit women aged 18-65 years, who will be randomly assigned to either a yoga group or a walking group.

Yoga Group: Participants in the yoga group will attend 90-minute yoga sessions, 3 times per week.

Walking Group: Participants in the walking group will engage in one-hour fast-paced walking sessions, 6 times per week.

Outcome Measures: Physical and metabolic markers will be assessed at baseline and after 8 months of exercise intervention. The primary outcomes will include changes in body weight, BMI, visceral fat, and basal metabolism. Metabolic biomarkers such as serum leptin, glucose, total cholesterol (TC), apolipoprotein A (APOA), and apolipoprotein B (APOB) will also be measured.

Participants will be monitored for adherence to the exercise protocol and any adverse events throughout the study. Data will be collected during the intervention, and analyzed to determine the differential effects of yoga and walking on the measured outcomes.

The study aims to provide insights into the relative benefits of yoga and walking exercise regimens on women's health, particularly in terms of body composition and metabolic health, thereby informing future exercise recommendations and health interventions.

• Study Type: Interventional
• Enrollment (Estimated): 84
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: jin li; Phone Number: (86)18438175639; Email: lijin0213@126.com

Study Locations

• China
  • Henan
    • Zhoukou, Henan, China
      • Recruiting
      • Zhou Kou Normal University
      • Contact: Jin Li

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

Female participants aged 18-65 years； Willing and able to participate in an 8-month exercise program； Generally healthy with no contraindications to physical activity； Ability to provide informed consent

Exclusion Criteria:

Current participation in a structured exercise program； Known cardiovascular, respiratory, or metabolic disorders that contraindicate exercise； Pregnancy or planning to become pregnant during the study period； Use of medications affecting metabolism or physical activity levels； Any other condition that, in the opinion of the investigators, would make participation unsafe or not feasible

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Yoga Group; Participants in this group will undergo 90-minute yoga sessions, 3 times per week, for 8 months. The yoga intervention includes a combination of asanas (postures), pranayama (breathing exercises), and meditation designed to improve flexibility, strength, and mental well-being.	Behavioral: Yoga; Participants in the yoga group will attend 90-minute yoga sessions, 3 times per week, for 8 months. The sessions will include a combination of asanas (postures), pranayama (breathing exercises), and meditation.
Experimental: Walking Group; Participants in this group will engage in one-hour fast-paced walking sessions, 6 times per week, for 8 months. The walking intervention is designed to improve cardiovascular fitness, endurance, and support weight loss.	Behavioral: Brisk walking; Participants in the brisk walking group will engage in one-hour fast-paced walking sessions, 6 times per week, for 8 months. The walking regimen is designed to improve cardiovascular fitness, endurance, and support weight loss.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Change in Body Weight	Measurement of body weight changes in kilograms from baseline to 8 months.	Baseline, 8 months
Change in Body Mass Index (BMI)	Measurement of BMI changes calculated as weight in kilograms divided by height in meters squared from baseline to 8 months.	Baseline, 8 months

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Change in Serum Leptin Levels	Measurement of serum leptin levels in ng/mL from baseline to 8 months.	Baseline, 8 months
Change in Fasting Blood Glucose Levels	Measurement of fasting blood glucose levels in mg/dL from baseline to 8 months.	Baseline, 8 months
Change in Total Cholesterol (TC) Levels	Measurement of total cholesterol levels in mg/dL from baseline to 8 months.	Baseline, 8 months

Collaborators and Investigators

• Sponsor: Zhoukou Normal University
• Investigators: Principal Investigator: xiaomeng liu, Zhoukou Normal University

Study record dates

Study Major Dates

• Study Start (Actual): January 3, 2024
• Primary Completion (Estimated): December 31, 2025
• Study Completion (Estimated): December 31, 2025

Study Registration Dates

• First Submitted: July 22, 2024
• First Submitted That Met QC Criteria: July 22, 2024
• First Posted (Actual): July 26, 2024

Study Record Updates

• Last Update Posted (Actual): July 26, 2024
• Last Update Submitted That Met QC Criteria: July 22, 2024
• Last Verified: July 1, 2024

More Information

Terms related to this study

• Keywords: Yoga, Walking, Exercise, Body Composition, Metabolic Health
• Additional Relevant MeSH Terms: Glucose Metabolism Disorders; Metabolic Diseases; Insulin Resistance; Hyperinsulinism; Metabolic Syndrome
• Other Study ID Numbers: ZhoukouNU-001

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO
• IPD Plan Description: The data will not be shared due to concerns about participant privacy and the sensitivity of the health data collected.

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No