Examining Different Modes of Exercise for Acute Reduction in Blood Pressure

October 4, 2024 updated by: Phil Chilibeck, University of Saskatchewan

Examining the Effects of Aerobic Exercise, Isometrics, and Stretching on Acute (Post-exercise) Blood Pressure Reduction

The purpose of the study is to compared different modes of exercise for eliciting post-exercise hypotension. The study will randomize 10 healthy participants to 30 minutes of either aerobic exercise, isometric exercise, stretching, or rest (control). Blood pressure and heart rate will be assessed before and for one hour post-exercise.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

The purpose is to compare different modes of exercise (aerobic vs. isometric vs. static stretching) for reducing blood pressure post-exercise. : Using a randomized crossover design, 5 male and 5 female (n=10) normotensive university students will participate in four different exercise sessions for 30 minutes: aerobic (cycle ergometer at 70% of VO2max), isometric (alternating wall-sit for 70% of max, and handgrip dynamometer at 30% of max for 2 minutes), stretching (targeting the larger muscle groups of the body), and control (rest). Participants' blood pressure and heart rate will be measured before each exercise session and monitored for 60 minutes afterwards to analyze the post-exercise hypotensive response.

Study Type

Interventional

Enrollment (Actual)

10

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Canada
    • Saskatchewan
      • Saskatoon, Saskatchewan, Canada, S7N5B2
        • University of Saskatchewan

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Able to safely perform exercise according to the Get Active Questionnaire

Exclusion Criteria:

  • Taking blood pressure medications

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Crossover Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Aerobic exercise
30 minutes of moderate-intensity aerobic exercise on a cycle ergometer
Behavioral: Exercise
Exercise involving aerobics, isometrics, and stretching
Experimental: Isometric exercise
30 minutes of isometric exercise (alternating hand-grip with wall-sitting)
Behavioral: Exercise
Exercise involving aerobics, isometrics, and stretching
Experimental: Static stretching
30 minutes of static stretching of major muscle groups
Behavioral: Exercise
Exercise involving aerobics, isometrics, and stretching
Active Comparator: Resting control
30 minutes of seated rest
Behavioral: Resting
Resting

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Change in systolic blood pressure (mmHg)
Time Frame: Baseline to 60 minutes after exercise
Baseline to 60 minutes after exercise
Change in diastolic blood pressure (mmHg)
Time Frame: Baseline to 60 minutes after exercise
Baseline to 60 minutes after exercise

Secondary Outcome Measures

Outcome Measure
Time Frame
Change in heart rate (beats per minute)
Time Frame: Baseline to 60 minutes after exercise
Baseline to 60 minutes after exercise
Change in rate-pressure product (beats per mintues x systolic blood pressure mmHg)
Time Frame: Change from baseline to 60 minutes after exercise
Change from baseline to 60 minutes after exercise

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Saskatchewan

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 4, 2024

Primary Completion (Actual)

April 10, 2024

Study Completion (Actual)

April 15, 2024

Study Registration Dates

First Submitted

October 3, 2024

First Submitted That Met QC Criteria

October 4, 2024

First Posted (Actual)

October 8, 2024

Study Record Updates

Last Update Posted (Actual)

October 8, 2024

Last Update Submitted That Met QC Criteria

October 4, 2024

Last Verified

October 1, 2024

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2023_24_09

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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