Multiple Joint, Structural Barbell Resistance Exercise Improves Information Processing Speed

August 27, 2020 updated by: Ting-Yu Lin, National Taiwan Normal University

Acute Multiple Joint, Structural Barbell Resistance Exercise Improves Information Processing Speed and Decreases Conflict-related Neural Activity in Older Adults: A Crossover, Sham Control, Randomized Control Trial With REP

This study investigated the effect of acute multiple joint, structural barbell resistance exercise on information processing speed and conflict-related neural activity in older adults via a crossover, sham control, randomized control trial.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

28

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Taiwan
      • Taipei, Taiwan
        • National Taiwan Normal University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

50 years to 65 years (Adult, Older Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

Male

Description

Inclusion Criteria:

  1. male adults aged 50-65 years old
  2. exercise ≥ 150 minutes/week
  3. normal or corrected-to-normal vision
  4. right-handed

Exclusion Criteria:

  1. dementia (MMSE ≥ 24)
  2. any medical condition listed on PARQ
  3. depression (BDI-II score ≤ 13)
  4. any diagnostic cardiovascular, neurological and other chronic diseases

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Other
  • Allocation: Randomized
  • Interventional Model: Crossover Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Resistance exercise
The experimental intervention is a session of resistance exercise described in the intervention section.
Behavioral: Resistance exercise
Barbell back squat, press, and deadlift for three sets of five repetitions with the weight closest to 75% of their estimated 1 repetition max. The participants were instructed to execute the movement with moderate speed (2s eccentric, 2s concentric, no pause in between). The rest period between sets and exercise movements was two to three minutes.
Active Comparator: Stretching exercise
The active control intervention is a session of stretching exercise described in the intervention section.
Behavioral: Stretching exercise (sham exercise)
Participants completed a passive stretching exercise session for a similar duration of time as the resistance exercise (≈ 30 min) as sham intervention, which included 15-20 stretching movements twice, holding each for 30 seconds as recommended by ACSM.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Change of Information processing speed between resistance and stretching exercises
Time Frame: 5-30 minutes before and 10-35 minutes after each intervention.
Choice reaction time of the Stroop test congruent condition. Unit: millisecond. Shorter reaction time means a better outcome.
5-30 minutes before and 10-35 minutes after each intervention.
Change of Inhibitory control between resistance and stretching exercises
Time Frame: 5-30 minutes before and 10-35 minutes after each intervention.
Interference score of the Stroop test. Unit: millisecond. Smaller interference score means a better outcome.
5-30 minutes before and 10-35 minutes after each intervention.

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Change of Conflict-related neural activity between resistance and stretching exercises
Time Frame: 5-30 minutes before and 10-35 minutes after each intervention.
N2b (event-related potential)
5-30 minutes before and 10-35 minutes after each intervention.
Change of Neural activity related to locus coeruleus phasic response between resistance and stretching exercises
Time Frame: 5-30 minutes before and 10-35 minutes after each intervention.
P3 (event-related potential)
5-30 minutes before and 10-35 minutes after each intervention.

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

National Taiwan Normal University

Investigators

  • Study Chair: Tsung-Min Hung, Ph.D., Department of Physical Education, National Taiwan Normal University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

August 1, 2017

Primary Completion (Actual)

August 1, 2019

Study Completion (Actual)

August 1, 2019

Study Registration Dates

First Submitted

August 25, 2020

First Submitted That Met QC Criteria

August 27, 2020

First Posted (Actual)

September 1, 2020

Study Record Updates

Last Update Posted (Actual)

September 1, 2020

Last Update Submitted That Met QC Criteria

August 27, 2020

Last Verified

August 1, 2020

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 201807HM004

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

The participant-level data and statistical code are available on request and the data will be anonymized.

IPD Sharing Time Frame

Three years within the publication.

IPD Sharing Supporting Information Type

  • STUDY_PROTOCOL
  • SAP
  • ICF
  • ANALYTIC_CODE

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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