Socket Seal Surgery

January 3, 2025 updated by: Nora Abdelgawad Mohamed, Al-Azhar University

Laser Assisted Socket Seal Surgery Using Bioactive Glass for Dental Implant Site Development

laser photo biomodulation (PBM) as a supplement to socket seal surgery

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

the role of PBM therapy as an adjunct for bioactive glass graft in SSS approaches

Study Type

Interventional

Enrollment (Actual)

45

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
      • Dakahlia, Egypt
        • , Faculty of Oral and Dental Medicine, Delta University for Science and Technology (DU), Dakahlia, Egypt

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Presence of at least a periodontal-affected and non-restorable tooth in posterior region (Class II sockets).
  • At least 10% plaque control scoring was accepted
  • A moderate to thick gingival phenotype

Exclusion Criteria:

  • systemic diseases or conditions that may compromise healing or bone metabolism,
  • having a history of radiotherapy, chemotherapy or bisphosphonate therapy, previous use of antibiotics in the last 3

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Triple

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Placebo Comparator: control group
platelet rich fibrin membrane
Biological: Platelet rich fibrin
10 ml of blood was withdrawn from the patient and immediately centrifuged for 10 minutes at 3000 revolutions/min and the layer of fibrin clot was obtained
Experimental: test 1 group
bioactive glass
Biological: Platelet rich fibrin
10 ml of blood was withdrawn from the patient and immediately centrifuged for 10 minutes at 3000 revolutions/min and the layer of fibrin clot was obtained
Biological: bioactive glass
supplied as resorbable form, (400-800um) particle siz
Active Comparator: test 2group
bioactive glass and Photobiomodulation
Biological: Platelet rich fibrin
10 ml of blood was withdrawn from the patient and immediately centrifuged for 10 minutes at 3000 revolutions/min and the layer of fibrin clot was obtained
Biological: bioactive glass
supplied as resorbable form, (400-800um) particle siz
Radiation: bioactive glass graft and PBM irradiation
The used laser parameters were set as: wavelength, 980 nm; power, 0.55 W; energy, 36 J; power density, 0.76 W cm2

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
alveolar ridge dimensional changes in height and width measures
Time Frame: at base line and after 9 months
at base line and after 9 months

Secondary Outcome Measures

Outcome Measure
Time Frame
bone biopsy
Time Frame: after 9 months
after 9 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Al-Azhar University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

Helpful Links

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

November 10, 2022

Primary Completion (Actual)

November 10, 2023

Study Completion (Actual)

February 10, 2024

Study Registration Dates

First Submitted

January 3, 2025

First Submitted That Met QC Criteria

January 3, 2025

First Posted (Actual)

March 25, 2025

Study Record Updates

Last Update Posted (Actual)

March 25, 2025

Last Update Submitted That Met QC Criteria

January 3, 2025

Last Verified

November 1, 2022

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • DU:024100558

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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