Relieving Surgical Pain and Nausea With Light Therapy (LITENS)

January 9, 2026 updated by: Nuran Ayşen Pamir Aksoy

Is It Possible to Reduce Surgical Pain and Nausea With Light Therapy? A Randomized Controlled, Non-Pharmacological Approach

The goal of this clinical trial is to investigate the effectiveness of colored (green and blue lens) glasses as a non-pharmacological method in relieving post-surgical pain and postoperative nausea in kidney donors. The main hypothesis it aims to test:

H1: Postoperative use of green-lensed glasses by patients who are kidney donors is effective in relieving surgical pain and postoperative nausea.

H2: Postoperative use of blue-lensed glasses by patients who are kidney donors is effective in relieving surgical pain and postoperative nausea.

Researchers will compare the blue-lens glasses and green-lens glasses groups to the transparent (colorless) glasses group and the non-glasses group to see if the colored lenses have an effect on postoperative pain and nausea.

Participants in the intervention groups will be asked

  • to wear the glasses (according to their randomly assigned group (blue/green/colorless/), immediately after they admitted to the ward postoperatively, at least 8 hours in a day, until their discharge
  • to respond the pain and nausea assessment (every 2 hours during postop day 1 and every 4 hours during postop day 2) until their discharge

Participants in the control group will be asked

- to respond the pain and nausea assessment (every 2 hours during postop day 1 and every 4 hours during postop day 2) until their discharge

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Since the hospital's architecture and clinical operation where the data will be collected have features that prevent patients from different groups from meeting, the single blind feature can be preserved. The pain assessment of the patients will be made with the numerical pain scale, and the nausea assessment will be made with the numerical nausea rating scale. In addition, data will be collected with the Patient Information Form prepared by the researchers in line with the literature.

Study Type

Interventional

Enrollment (Actual)

48

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey (Türkiye)
    • Atakent
      • Istanbul, Atakent, Turkey (Türkiye), 34752
        • Acibadem Atakent Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Being a donor for kidney transplantation
  • Not having an obstacle to wearing glasses
  • Being able to communicate verbally

Exclusion Criteria:

  • Being color blind • Developing post-operative complications during the study period

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Supportive Care
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Study Group-Blue lens glasses
Patients who assigned to this group will wear blue-lens glasses postoperatively (min 8 h in a day)
Device: blue colored lens glasses
Researchers will compare the blue-lens glasses and green-lens glasses groups to the transparent (colorless) glasses group and the non-glasses group to see if the colored lenses have an effect on postoperative pain and nausea.
Other Names:
  • blue lens glasses
  • colored lens glasses
Experimental: Study Group-Green lens glasses
Patients who assigned to this group will wear green-lens glasses postoperatively (min 8 h in a day)
Device: green colored lens glasses
Researchers will compare the blue-lens glasses and green-lens glasses groups to the transparent (colorless) glasses group and the non-glasses group to see if the colored lenses have an effect on postoperative pain and nausea.
Other Names:
  • green lens glasses
Placebo Comparator: Study Group-colorless (transparent) lens glasses
Patients who assigned to this group will wear colerless (transparanet)-lens glasses postoperatively (min 8 h in a day)
Device: colorless (transparent) lens glasses
Researchers will compare the blue-lens glasses and green-lens glasses groups to the transparent (colorless) glasses group and the non-glasses group to see if the colored lenses have an effect on postoperative pain and nausea.
No Intervention: Control group
Patients in this group will not be wearing any glasses. Patients will be asked to participate for postoperative pain and nausea assesment.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Post-operative pain
Time Frame: every 2 h during the post operative day1, and every 4 h during postoperative day 2.
Post-operative pain level according to the numerical pain assessment scale
every 2 h during the post operative day1, and every 4 h during postoperative day 2.
Post-operative nausea
Time Frame: every 2 h during the post operative day1, and every 4 h during postoperative day 2.
Postoperative nausea level according to the numerical nausea rating scale
every 2 h during the post operative day1, and every 4 h during postoperative day 2.

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Nuran Ayşen Pamir Aksoy

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 14, 2025

Primary Completion (Actual)

December 30, 2025

Study Completion (Actual)

December 30, 2025

Study Registration Dates

First Submitted

January 10, 2025

First Submitted That Met QC Criteria

January 10, 2025

First Posted (Actual)

January 13, 2025

Study Record Updates

Last Update Posted (Estimated)

January 12, 2026

Last Update Submitted That Met QC Criteria

January 9, 2026

Last Verified

January 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2024-18-687

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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