Incidence of Chronic Pain After Video-Assisted Thoracic Surgery

Video-assisted thoracic surgery (VATS) is frequently performed in thoracic surgery. It is widely accepted that VATS causes acute pain. Many factors such as postoperative analgesia treatment plan, operation time, number of chest tubes, and duration of chest tube stay can affect acute pain. This acute pain prolongs the discharge time of the patients and increases the frequency of postoperative pulmonary complications and postoperative morbidity. Postoperative acute pain may cause chronic pain in the later period, and may adversely affect the quality of life of the patients.

This study, it was aimed to analyze the symptoms of chronic pain in the 1st and 3rd months postoperatively in patients who had undergone VATS.

Study Overview

• Status: Recruiting
• Conditions: Postoperative Pain; Postoperative Pain, Acute; Postoperative Pain, Chronic; VATS
• Intervention / Treatment: Procedure: VATS application

• Study Type: Observational
• Enrollment (Anticipated): 100

Contacts and Locations

• Study Contact: Name: Oya Kaybal, MD; Phone Number: 00905438760088; Email: kaybaloya@gmail.com
• Study Contact Backup: Name: Musa Zengin, MD; Phone Number: 00905307716235; Email: musazengin@gmail.com

Study Locations

• Turkey
  • Ankara
    • Keçiören, Ankara, Turkey, 06290
      • Recruiting
      • Ankara Atatürk Chest Disease and Chest Surgery Training and Research Hospital
      • Contact: Oya Kaybal, MD; Phone Number: +905079193765; Email: kaybaloya@gmail.com
      • Contact: Musa Zengin, MD; Phone Number: +905307716235

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 65 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

Patients between the ages of 18-65 years, in the ASA I-II-III risk group, with a BMI between 18-35 kg/m2 and undergoing VATS will be included in our study.

Patients under the age of 18 years and over the age of 65 years, with an ASA score of IV and above, with a BMI below 18 kg/m2 and above 35 kg/m2, who were operated under emergency conditions, and who received chronic pain treatment will be excluded from the study.

Description

Inclusion Criteria:

• Age between 18 and 65 years
• American Society of Anesthesiologists physical status I-II-III
• Body mass index between 18-35 kg/m2
• Patients undergoing elective VATS

Exclusion Criteria:

• Advanced cancer
• History of chronic analgesic therapy
• Patients with previous thoracic surgery
• Patients who were operated under emergency conditions

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Pain scores at 1st months.	Chronic pain symptoms will be assessed using the visual analog scale on a scale from 0 (no pain) to 10 (worst pain). Neuropathic pain symptoms (Burning, stabbing, electric shock-like pain, tingling, numbness, pins, and needles feeling, hyperalgesia, allodynia, and hypoesthesia) will also be asked to the patients in the 1st month after surgery.	Chronic pain symptoms at 1st months
Pain scores at 3rd months	Chronic pain symptoms will be assessed using the visual analog scale on a scale from 0 (no pain) to 10 (worst pain). Neuropathic pain symptoms (Burning, stabbing, electric shock-like pain, tingling, numbness, pins, and needles feeling, hyperalgesia, allodynia, and hypoesthesia) will also be asked to the patients in the 3rd month after surgery.	Chronic pain symptoms at 3rd months

Collaborators and Investigators

• Sponsor: Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
• Investigators: Principal Investigator: Oya Kaybal, MD, Atatürk Chest Diseases and Chest Surgery Training and Research Hospital

Study record dates

Study Major Dates

• Study Start (Actual): December 14, 2021
• Primary Completion (Anticipated): June 14, 2022
• Study Completion (Anticipated): July 14, 2022

Study Registration Dates

• First Submitted: December 24, 2021
• First Submitted That Met QC Criteria: December 24, 2021
• First Posted (Actual): January 11, 2022

Study Record Updates

• Last Update Posted (Actual): January 11, 2022
• Last Update Submitted That Met QC Criteria: December 24, 2021
• Last Verified: December 1, 2021

More Information

Terms related to this study

• Keywords: Postoperative Pain; VATS; Postoperative Pain, Acute; Postoperative Pain, Chronic
• Additional Relevant MeSH Terms: Pathologic Processes; Postoperative Complications; Pain; Neurologic Manifestations; Pain, Postoperative; Chronic Pain; Acute Pain
• Other Study ID Numbers: 2012-KAEK-15/2446

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No