The Effect of Olive Oil and Centaury Oil on Rash

Investigation of the Effect of Olive Oil and Centaury Oil in the Management of Diaper Dermatitis

Diaper dermatitis is a preventable health problem. No study evaluating the efficacy of centaury oil in diaper dermatitis was found in the literature. This study will be conducted to investigate the effect of olive oil and centaury oil in the management of diaper dermatitis.

Study Overview

• Status: Completed
• Conditions: Diaper Dermatitis
• Intervention / Treatment: Other: Control

Detailed Description

Diaper dermatitis is estimated to have an incidence of between 7% and 35%, although the prevalence cannot be determined precisely because it is not usually seen as a disease by parents and most patients are treated at home. Prevention of diaper dermatitis should be the main approach in treatment and care. Once it occurs, the aim of treatment is to accelerate the healing of the damaged area and prevent its spread. In the prevention and treatment of diaper dermatitis, practices such as ventilating the baby's diaper, changing the diaper frequently, keeping the area dry, cleaning with appropriate methods, using barrier creams and not tying the diaper tightly have been reported to be beneficial.

In the literature, studies using methods such as water, herbal cream (chamomile cream, calendula cream, aloe vera cream), barrier cream (zinc oxide) and herbal mixture (honey, beeswax, olive oil) were found in the treatment of infants with mild to moderate diaper dermatitis. It has been stated that the rates of diaper dermatitis will continue to increase if parents are not given adequate information about appropriate care and which products are beneficial or even harmful. In conclusion, diaper dermatitis is a preventable health problem. No study evaluating the efficacy of olive oil and centaury oil in diaper dermatitis was found in the literature. This study will be conducted to examine the effect of olive oil and centaury oil in the management of diaper dermatitis.

• Study Type: Interventional
• Enrollment (Actual): 45
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Turkey (Türkiye)
  • Mardin, Turkey (Türkiye)
    • Mardin Training and Research Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

• The baby has mild diaper dermatitis according to the diaper dermatitis severity rating scale
• The baby receives antibiotic treatment
• The baby gets additional food
• The baby is between 6-18 months

Exclusion Criteria:

• Infants with moderate or severe diaper dermatitis according to the diaper dermatitis severity rating scale
• Babies with open wounds on the perineum,
• Babies with any skin disease
• Babies who use barrier creams or special oils in routine care

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Supportive Care
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Olive Oil Application; The degree of diaper dermatitis will be evaluated before and after the procedure (72 hours after the first procedure) using the 'Uncomplicated Diaper Dermatitis Severity Rating Scale in Infants'. After cleaning the perineum as described to the mothers, they will be asked to apply olive oil to the perineum four times a day, 1 cc each time.	Other: Control; The degree of diaper dermatitis of the babies will be evaluated before and after the procedure (72 hours after the first procedure) by using the 'Uncomplicated Diaper Dermatitis Severity Rating Scale in Babies (UNDDCS)'. Mothers will be asked to diaper their babies with cotton wool soaked with clear water.
Experimental: Centaury Oil Application; The degree of diaper dermatitis of the infants will be evaluated before and after the procedure (72 hours after the first procedure) using the 'Uncomplicated Diaper Dermatitis Severity Rating Scale in Infants'. After cleaning the perineum as described to the mothers, they will be asked to apply centaury oil to the perineum four times a day, 1 cc each time.	Other: Control; The degree of diaper dermatitis of the babies will be evaluated before and after the procedure (72 hours after the first procedure) by using the 'Uncomplicated Diaper Dermatitis Severity Rating Scale in Babies (UNDDCS)'. Mothers will be asked to diaper their babies with cotton wool soaked with clear water.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Outcome Measures	The outcome measures for the sociodemographic data of the study will be collected by using the 'Introductory Information Form', which includes questions about the infant's identifying characteristics such as gender, age, height, weight and diaper care. The other outcome measure to be used in the study is the 'Uncomplicated Diaper Dermatitis Severity Rating Scale in Infants' which will be used to rate the severity of diaper dermatitis in infants. Uncomplicated Diaper Dermatitis Severity Rating Scale in Infants: The lowest score that can be obtained from the scale consisting of a total of four items is zero and the highest score is six. The minimum and maximum scores that can be obtained from each item are 0-3 points for the severity of erythema or irritation item, 0-1 point for the degree of diaper dermatitis item, 0-1 point for the papules and pustules item and 0-1 point for the open skin item. As the score on the scale increases, the degree of diaper dermatitis also increases	1 year

Collaborators and Investigators

• Sponsor: Harran University
• Investigators: Study Director: H YAĞMUR SEVİNÇ AKIN, Assistant Professor, Harran University; Principal Investigator: MAKSUDE YILDIRIM, Assistant Professor, Adiyaman University; Principal Investigator: BARIŞ AKIN, Specialist nurse, Mardin Training and Research Hospital; Principal Investigator: NESRİN ŞEN CELASİN, Assoc. Professor, Celal Bayar University; Principal Investigator: ZÜLEYHA GÜRDAP, RESEARCH ASSISTANT, Inonu University

Study record dates

Study Major Dates

• Study Start (Actual): December 30, 2024
• Primary Completion (Actual): June 30, 2025
• Study Completion (Actual): June 30, 2025

Study Registration Dates

• First Submitted: January 3, 2025
• First Submitted That Met QC Criteria: January 23, 2025
• First Posted (Actual): January 30, 2025

Study Record Updates

• Last Update Posted (Actual): December 30, 2025
• Last Update Submitted That Met QC Criteria: December 23, 2025
• Last Verified: December 1, 2025

More Information

Terms related to this study

• Keywords: olive oil; diaper dermatitis; centaury oil
• Additional Relevant MeSH Terms: Skin Diseases; Skin Diseases, Eczematous; Dermatitis; Dermatitis, Irritant; Dermatitis, Contact; Skin and Connective Tissue Diseases; Diaper Rash
• Other Study ID Numbers: HRU-VSYO-HYSA-2024/139

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No