High-Load Blood Flow Restriction (BFR) Training May Decrease Anaerobic Fatigue in Distance Runners (BFR-Training)

February 6, 2025 updated by: Tuğba Kocahan, Gulhane Training and Research Hospital

High-Load Blood Flow Restriction (BFR) Training May Decrease Anaerobic Fatigue in Distance Runners: A Randomized Controlled Trial

This study investigates the effects of high-load BFR training on anaerobic performance and fatigue resistance in distance runners. To determine whether adding BFR to isokinetic resistance training improves anaerobic performance and 5-10 km running times in runners. Forty-two runners were randomized into BFR (n=21) and control (n=21) groups. Both groups followed an identical 8-week isokinetic training protocol twice weekly. The BFR group performed exercises with arterial occlusion pressure set to 80% of the measured occlusion pressure. Anaerobic performance was assessed via the Wingate test, and 5 km and 10 km running times were recorded before and after the intervention. Statistical analyses compared pre- and post-training performance within and between groups.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Blood flow restriction (BFR) training is increasingly used to enhance athletic performance, but its effects on anaerobic fatigue in distance runners remain unclear. This study investigates the effects of high-load BFR training on anaerobic performance and fatigue resistance in distance runners.To determine whether adding BFR to isokinetic resistance training improves anaerobic performance and 5-10 km running times in runners.

Forty-two runners were randomized into BFR (n=21) and control (n=21) groups. Both groups followed an identical 8-week isokinetic training protocol twice weekly. The BFR group performed exercises with arterial occlusion pressure set to 80% of the measured occlusion pressure. Anaerobic performance was assessed via the Wingate test, and 5 km and 10 km running times were recorded before and after the intervention. Statistical analyses compared pre- and post-training performance within and between groups.

Study Type

Interventional

Enrollment (Actual)

42

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey
      • Ankara, Turkey, 06018
        • University of Health Sciences, Gulhane Faculty of Medicine
      • Ankara, Turkey, 06018
        • Hüseyin Günaydın

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • The absence of cardiovascular or musculoskeletal conditions,
  • No recent resistance training,
  • Running more than 20 kilometers per week.

Exclusion Criteria:

  • Having a cardiovascular or musculoskeletal condition,
  • Having done recent resistance training,
  • Running less than 20 kilometers per week.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Other
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Blood flow restriction (BFR) Group
BFR group followed an identical 8-week isokinetic training protocol twice weekly. The BFR group performed exercises with arterial occlusion pressure set to 80% of the measured occlusion pressure.
Device: Blood flow restriction (BFR) training
Both groups followed an identical 8-week isokinetic training protocol twice weekly. The BFR group performed exercises with arterial occlusion pressure set to 80% of the measured occlusion pressure.
Other Names:
  • Isokinetic training
Device: Isokinetic training
Both groups followed an identical 8-week isokinetic training protocol twice weekly.
Active Comparator: Control Group
Control group followed an identical 8-week isokinetic training protocol twice weekly.
Device: Isokinetic training
Both groups followed an identical 8-week isokinetic training protocol twice weekly.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
The effects of an isokinetic training program combined with blood flow restriction (BFR) on anaerobic performance and fatigue resistance in long-distance runners were investigated.
Time Frame: baseline and week 8
Lower extremity Wingate Test (WanT) was used to evaluate the anaerobic capacities of long-distance runners. In calculating the fatigue index; (peak power - minimum power/peak power) x 100 (% fatigue index) formula was used.
baseline and week 8

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Gulhane Training and Research Hospital

Investigators

  • Study Chair: Hüseyin Günaydın, University of Health Sciences, Gulhane Faculty of Medicine, Ankara/Türkiye

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

July 15, 2022

Primary Completion (Actual)

May 15, 2023

Study Completion (Actual)

July 15, 2024

Study Registration Dates

First Submitted

February 2, 2025

First Submitted That Met QC Criteria

February 6, 2025

First Posted (Actual)

March 25, 2025

Study Record Updates

Last Update Posted (Actual)

March 25, 2025

Last Update Submitted That Met QC Criteria

February 6, 2025

Last Verified

February 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • SBU-GTF

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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