Ventilatory Functions and Physical Intolerance in ESRD Adolescents: Response to Program of Walking With Dogs

Fatigue, Ventilatory Functions, Physical Intolerance, and Life Quality in ESRD Adolescents: Response to Program of Walking With Dogs

adolescents with chronic renal failure going on hemodialysis usually complain many problems including compromised ventilation, early fatigue, early physical intolerance, and bad life quality. incentive spirometer is highly recommended to improve these problems. also, walking program, especially walking with dog, can increase the benefits of incentive spirometer

Study Overview

• Status: Recruiting
• Conditions: End Stage Renal Disease; Hemolysis
• Intervention / Treatment: Other: incentive spirometer and walking with dog; Other: training by incentive spirometer only

Detailed Description

End stage renal diseased adolescents (numbering forty) will be grouped randomly to two random groups, twenty adolescents in group I or group II. Both groups will trained by incentive spirometer 30 min during the sessions of dialysis three applications weekly for 12 weeks. Group I will additionally walked freely with a dog 30 min three times weekly (in opposite days of hemodialysis). The duration of this trial will be 12 weeks.

• Study Type: Interventional
• Enrollment (Estimated): 40
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Ali MA Ismail, lecturer; Phone Number: 01005154209; Email: ali.mohamed@pt.cu.edu.eg
• Study Contact Backup: Name: shymaa bondok, lecturer; Phone Number: 0201223749627; Email: dr.shaimaa.bondok@dtu.edu.eg

Study Locations

• Egypt
  • Giza
    • Dokki, Giza, Egypt, 11432
      • Recruiting
      • Faculty of Physical Therapy Cairo University
      • Contact: Ali MA Ismail, lecturer; Phone Number: +201005154209; Email: ali.mohamed@pt.cu.edu.eg
      • Contact: shymaa bondok, lecturer; Phone Number: 0201223749627; Email: dr.shaimaa.bondok@dtu.edu.eg

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

• adolescents (forty) with ESRD
• patents on regular hemodiaysis

Exclusion Criteria:

• cardiac insult
• respiratory insult
• orthopedic problem
• liver insult

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Prevention
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: group number 1; End stage renal diseased adolescents (numbering twenty) will trained by incentive spirometer 30 min during the sessions of dialysis three applications weekly for 12 weeks. they will additionally walked freely with a dog 30 min three times weekly (in opposite days of hemodialysis). The duration of this trial will be 12 weeks.	Other: incentive spirometer and walking with dog; End stage renal diseased adolescents (numbering twenty) will trained by incentive spirometer 30 min during the sessions of dialysis three applications weekly for 12 weeks. they will additionally walked freely with a dog 30 min three times weekly (in opposite days of hemodialysis). The duration of this trial will be 12 weeks.
Active Comparator: group number 2; End stage renal diseased adolescents (numbering twenty) will trained by incentive spirometer 30 min during the sessions of dialysis three applications weekly for 12 weeks.	Other: training by incentive spirometer only; End stage renal diseased adolescents (numbering twenty) will trained by incentive spirometer 30 min during the sessions of dialysis three applications weekly for 12 weeks.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
six minute walk testing	it is a physical capacity measure	it will be measured after 12 weeks

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
forced vital capacity	it is a pulmonary function test	it will be measured after 12 weeks
forced expiratory volume at first second	it is a pulmonary function test	it will be measured after 12 weeks
maximal inspiratory pressure	it is a test measures strength of inspiratory muscles	it will be measured after 12 weeks
child health questionnaire (physical summary)	the parent form (50 questions) will used to measure quality of life	it will be measured after 12 weeks
child health questionnaire (mental summary)	the parent form (50 questions) will used to measure quality of life	it will be measured after 12 weeks
fatigue symptoms inventory	it is a questionnaire assesses fatigue	it will be measured after 12 weeks

Collaborators and Investigators

• Sponsor: Cairo University
• Investigators: Principal Investigator: Ali MA Ismail, lecturer, Cairo University

Study record dates

Study Major Dates

• Study Start (Actual): February 5, 2025
• Primary Completion (Estimated): June 1, 2025
• Study Completion (Estimated): June 5, 2025

Study Registration Dates

• First Submitted: March 3, 2025
• First Submitted That Met QC Criteria: March 3, 2025
• First Posted (Actual): March 25, 2025

Study Record Updates

• Last Update Posted (Actual): March 25, 2025
• Last Update Submitted That Met QC Criteria: March 3, 2025
• Last Verified: March 1, 2025

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Urogenital Diseases; Pathologic Processes; Male Urogenital Diseases; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Chronic Disease; Disease Attributes; Renal Insufficiency; Renal Insufficiency, Chronic; Kidney Failure, Chronic; Hemolysis
• Other Study ID Numbers: IRB00014233-25

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No