Conservative Versus Operative Management in Adhesive Intestinal Obstruction

March 8, 2025 updated by: Osama Khaled Ahmed, Sohag University

Role of Conservative Management in Adhesive Intestinal Obstruction Versus Operative Management

This study aims to evaluate the role of Conservative management in patients with adhesive Intestinal Obstruction Regarding the selection criteria of the patients, duration of conservative route, success rate, and recurrence of adhesions and avoiding the surgical route complications.

Study Overview

Status

Completed

Conditions

Detailed Description

Adhesive Intestinal Obstruction is very common and represents a serious life threatening condition, which can be caused by congenital band, following abdominal surgeries and other medical conditions like tuberculosis.

The management options for adhesive intestinal obstruction (AIO) could be operative treatment (open-laparoscopy) or non-operative (conservative management) according to many reasons.

Some reports indicate that the operative management for adhesive Intestinal obstruction lead to further adhesions in the future in addition to other possible complications (anaesthetic - iatrogenic injury during adhesolysis - wound site infections - illius-long hospital stay).

The Conservative route is recommended in all patients except those with signs of peritonitis, strangulation, or bowel ischemia which would have been diagnosed during physical examination and imaging.

A few studies compared the advantages, safety, and less complications of Conservative versus operative management. Therefore, this study will be conducted on patients with adhesive Intestinal Obstruction to compare the effectiveness of Conservative versus operative management regarding the selection criteria for the patients, the duration of the Conservative route, things to be done and what need to be observed during the conversation time.

Study Type

Observational

Enrollment (Actual)

50

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
      • Sohag, Egypt
        • Faculty of Medicine, Sohag University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Probability Sample

Study Population

patients with adhesive Intestinal Obstruction at Department of General Surgery, Oncological and Laparoscopic Surgeries, Sohag University Hospitals, Sohag, Egypt

Description

Inclusion Criteria:

  • Age 6-70 years.
  • Both sexes.
  • Complete \ Partial adhesive Intestinal Obstruction, with CT Abdomen and pelvis with oral and IV Contrast.

Exclusion Criteria:

  • Patients with signs of Strangulation
  • Patients with signs of peritonitis.
  • Patients with signs of bowel ischemia
  • Failure of Conservative management for more than 72 hours.
  • Vitally unstable patients
  • Patients with comorbidities which need rapid interventions.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
X-Ray Changes
Time Frame: 72 Hours
Daily Chest Abdomen X-ray Erect copies to evaluate the improvement of the Intestinal Obstruction through evaluation of the X-ray findings (Air fluid levels).
72 Hours
Passability Status
Time Frame: 72 Hours
Daily history taking records and per rectal examination findings to evaluate the passability status (stool /flatus)
72 Hours
Hospital Stay Duration
Time Frame: from 3 to 5 days.
The Conservative management in patients with adhesive Intestinal Obstruction will avoid them the surgical route which requires long hospital stay postoperative
from 3 to 5 days.
Vomiting
Time Frame: 72 Hours
Frequency and severity of vomiting will be collected to help in prognosis prediction
72 Hours
Abdominal Signs
Time Frame: 72 Hours
Data collected about Daily abdominal examination findings (Distention, Intestinal sounds, abdominal pain and Per rectal examination).
72 Hours

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Recurrence of Attacks
Time Frame: two years previous the onset of the current attack. (During the last two years before the admission)
past history about the previous attacks of the adhesive Intestinal Obstruction
two years previous the onset of the current attack. (During the last two years before the admission)
Past Surgical History
Time Frame: two years previous the onset of the current attack. (During the last two years before the admission)
Detailed history about the previous operations to determine the relationship between different operations and adhesive Intestinal Obstruction
two years previous the onset of the current attack. (During the last two years before the admission)

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Sohag University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

April 1, 2024

Primary Completion (Actual)

September 1, 2024

Study Completion (Actual)

January 1, 2025

Study Registration Dates

First Submitted

February 24, 2025

First Submitted That Met QC Criteria

March 8, 2025

First Posted (Actual)

March 25, 2025

Study Record Updates

Last Update Posted (Actual)

March 25, 2025

Last Update Submitted That Met QC Criteria

March 8, 2025

Last Verified

March 1, 2025

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • Soh-Med--25-1-09MS

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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