- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT06876220
The Role of Anchoring and Distraction in the Effectiveness of Mindfulness on Reducing Emotional Reactivity
July 20, 2025 updated by: Professor Lam Shui-fong, The University of Hong Kong
The current study aims to investigate the effectiveness of the 8-week Mindfulness-Based Cognitive Therapy for Life (MBCT-L) on the use of anchoring and distraction as emotion care/regulation strategies.
It is hypothesized that anchoring and distraction are related but different processes, which could be evidenced by fMRI.
The investigators further hypothesized that mindfulness training could lead to functional changes in the brain, which could also be evidenced by fMRI.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
To test the hypotheses, the participants will be randomly allocated to either the experimental group or the waitlist control group.
Both groups will complete behavioral measures and an fMRI experiment before the experimental group's intervention (T0).
The experimental group will receive Mindfulness-Based Cognitive Therapy for Life (MBCT-L) between T0 and T1, while the waitlist control will receive no treatment during this period.
Both groups will complete the behavioral measures and the fMRI experiment again after the experimental group finishes the MBCT-L course (T1).
Study Type
Interventional
Enrollment (Actual)
42
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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-
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Hong Kong, Hong Kong
- Jockey Club "Peace and Awareness" Mindfulness Culture in Schools Initiative, Faculty of Social Sciences, The University of Hong Kong
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
Accepts Healthy Volunteers
Yes
Description
Inclusion Criteria:
- Right-handed
- Currently registered in post-graduated program with professional counselling training
Exclusion Criteria:
- History of neurological or other disorders affecting the brain (such as encephalitis, epilepsy, birth defects, or polio)
- Have experienced a concussion, head or brain trauma, seizures, loss of consciousness
- Have been injured in the eye by a metallic foreign body.
- Have been injured by metallic foreign body (e.g. bullet, shrapnel)
- History of sickle cell anemia/kidney disease/diabetes, asthma, or allergies
- Long-term use of medication is required
- Currently pregnant or breast feeding.
Had the following conditions or implants in their body:
- Surgical clips
- Cardiac pacemaker
- Neurostimulator/internal electrodes
- Insulin pump
- Internal shunt
- Metal screen / suture
- Cochlear implants
- Hearing aid
- Eye implants/eyelid springs
- Orthopaedic devices (e.g. pins, nails, screws)
- Prosthetic heart valve
- Breast tissue expander
- Tattoo or permanent eye-lining
- Body ring
- Patch/Blood Glucose Monitor
- Dentures
- Intrauterine contraceptive device
- Metal blockage in the blood vessel/metal foreign body in the body
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: intervention group
Participants will receive an 8-week mindfulness-based group intervention, namely Mindfulness-based Cognitive Therapy for Life (MBCT-L).
|
MBCT-L is an 8-week group intervention where participants are guided to practice mindfulness and cognitive exercise.
The course covers themes such as anchoring, acceptance, and decentering.
The course will be provided by mindfulness teachers who have completed the training offered by Oxford Mindfulness Foundation (OMF).
Throughout the eight weeks, the course guides the participants through various themes such as anchoring, acceptance, and decentering.
The sessions involve guided mindfulness practices, reflection, discussion, inquiry, and weekly home practice.
The language of instruction is Cantonese.
|
|
No Intervention: waitlist controlled group
Participants in the wait-list control group will receive the same intervention, two months after the experimental group completed the intervention.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Brain activation during the emotion care/regulation task
Time Frame: Baseline (2 weeks before the intervention), Post-intervention (14-16 weeks after baseline)
|
BOLD signal contrast when the participants performing an emotion counting Stroop task.
|
Baseline (2 weeks before the intervention), Post-intervention (14-16 weeks after baseline)
|
|
Reaction time during the emotion care/regulation task
Time Frame: Baseline (2 weeks before the intervention), Post-intervention (14-16 weeks after baseline)
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Reaction time of the correct response in the emotion counting Stroop task.
|
Baseline (2 weeks before the intervention), Post-intervention (14-16 weeks after baseline)
|
|
Accuracy during the emotion care/regulation task
Time Frame: Baseline (2 weeks before the intervention), Post-intervention (14-16 weeks after baseline)
|
Accuracy of the emotion counting Stroop task.
|
Baseline (2 weeks before the intervention), Post-intervention (14-16 weeks after baseline)
|
|
Mindfulness
Time Frame: Baseline (2 weeks before the intervention), Post-intervention (14-16 weeks after baseline), Follow-up (22-24 weeks after baseline)
|
The mean score of Cognitive and Affective Mindfulness Scale-Revised (CAMS-R, Feldman, Hayes, Kumar, Greeson, & Laurenceau, 2007) is a self-report 5-point Likert scale measuring individual differences in mindfulness that includes 12 items.
The mean score ranged from 1 to 5. A higher score means a higher level of mindfulness, i.e. an expected outcome from an effective mindfulness intervention.
|
Baseline (2 weeks before the intervention), Post-intervention (14-16 weeks after baseline), Follow-up (22-24 weeks after baseline)
|
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Psychological well-being
Time Frame: Baseline (2 weeks before the intervention), Post-intervention (14-16 weeks after baseline), Follow-up (22-24 weeks after baseline)
|
The mean score of Psychological Well-being Scale (PWBS; Ryff et al., 1995) includes 18 items measuring 6 aspects of wellbeing and happiness: autonomy, environmental mastery, personal growth, positive relations with others, purpose in life, and self-acceptance.
Participants used a 5-point Likert scale, ranging from 1 = highly disagree to 5 = highly agree, to rate the 18 statements.
The mean score ranged from 1 to 5. A higher score means a higher level of psychological well-being, i.e. an expected outcome from an effective mindfulness intervention.
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Baseline (2 weeks before the intervention), Post-intervention (14-16 weeks after baseline), Follow-up (22-24 weeks after baseline)
|
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Use of distraction as a emotion care/regulation strategy
Time Frame: Baseline (2 weeks before the intervention), Post-intervention (14-16 weeks after baseline), Follow-up (22-24 weeks after baseline)
|
The mean scores of five items of the self-developed scale to assess the use of distraction and its connection to attentional deployment with a pilot test.
Participants used a 5-point Likert scale, ranging from 1 = never to 5 = always, to rate the five statements.
The mean score ranged from 1 to 5. A higher score indicates a greater tendency to employ distraction as an emotion regulation strategy.
It's important to note that the score only reflects the habitual usage of this strategy and does not imply a better or worse outcome.
|
Baseline (2 weeks before the intervention), Post-intervention (14-16 weeks after baseline), Follow-up (22-24 weeks after baseline)
|
|
Use of anchoring as a emotion care/regulation strategy
Time Frame: Baseline (2 weeks before the intervention), Post-intervention (14-16 weeks after baseline), Follow-up (22-24 weeks after baseline)
|
The mean score of five items of the self-developed scale to assess the use of anchoring with a pilot test.
Participants used a 5-point Likert scale, ranging from 1 = never to 5 = always, to rate the five statements.
The mean score ranged from 1 to 5. A higher score indicates a greater tendency to employ distraction as an emotion regulation strategy.
It's important to note that the score only reflects the habitual usage of this strategy and does not imply a better or worse outcome.
|
Baseline (2 weeks before the intervention), Post-intervention (14-16 weeks after baseline), Follow-up (22-24 weeks after baseline)
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Study Director: Shui-fong Lam, PhD, The University of Hong Kong
- Principal Investigator: Gloria HY Wong, The University of Hong Kong
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
September 1, 2023
Primary Completion (Actual)
January 21, 2025
Study Completion (Actual)
February 13, 2025
Study Registration Dates
First Submitted
November 26, 2023
First Submitted That Met QC Criteria
March 9, 2025
First Posted (Actual)
March 14, 2025
Study Record Updates
Last Update Posted (Actual)
July 24, 2025
Last Update Submitted That Met QC Criteria
July 20, 2025
Last Verified
July 1, 2025
More Information
Terms related to this study
Other Study ID Numbers
- UHongKong(JC PandA_fMRI)
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
product manufactured in and exported from the U.S.
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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