Clinical Success of Onlays Fabricated With Different Types of Resin

September 9, 2025 updated by: Esra Cengiz Yanardag, Mersin University

One-year Clinical Evaluation of Onlay Restorations Fabricated With Three Different Additive Manufacturing Resins in Endodontically Treated Teeth: A Prospective Study

Additive manufacturing, also referred to as "3D printing" or "rapid prototyping," is defined as the process of joining materials layer by layer to create an object based on 3D model data. In this method, a digital data set is first created on a computer (computer-aided design, CAD) and then transferred to a 3D printer. The designed object is produced by printing it in successive layers.

In contrast, in subtractive manufacturing, restorations are produced by milling homogeneous blocks based on computer-designed models. Compared to subtractive manufacturing technology, additive manufacturing allows for the production of more complex, detailed, and larger structures with much less material waste and without excessive use of force.

It is thought that additive manufacturing has the potential to overcome the disadvantages of subtractive manufacturing. Over the past decade, global sales of industrial and personal 3D printers, materials, and services have increased by more than 33% annually.

Due to its success in the production of surgical guides, temporary and permanent restorations, crowns and bridges, occlusal splints, frameworks, and orthodontic appliances, this technology has attracted significant interest in the field of dentistry.

Although additive manufacturing has started to be used as an alternative to subtractive manufacturing in many applications, there is still a lack of information regarding the chemical composition, mechanical, and physical properties of printable resins. Moreover, clinical data on the use of these resins in permanent restorations are quite limited.

Therefore, the aim of this study is to clinically evaluate and monitor for one year the performance of onlay restorations fabricated with three different resins of varying compositions in endodontically treated teeth.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

48

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • Turkey (Türkiye)
    • Mersin
      • Mersin, Mersin, Turkey (Türkiye), 33150
        • Recruiting
        • Mersin University Faculty of Dentistry
        • Principal Investigator:
          • Esra Cengiz Yanardag, DDS, PhD
        • Contact:
        • Contact:
      • Mersin, Mersin, Turkey (Türkiye), 33343
        • Not yet recruiting
        • Mersin University
        • Contact:
        • Contact:
        • Principal Investigator:
          • Esra Cengiz Yanardag, DDS, PhD
        • Sub-Investigator:
          • Ezgi Guven, DDS

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Molar teeth that have undergone root canal treatment
  • Teeth with proximal defects located above the gingival margin
  • Defects limited to the occlusal surface and a single adjacent surface
  • Presence of an occlusal defect extending over one-third of the distance between the fissure and the cusp tip and involving one or more cusps
  • Presence of an opposing tooth or a fixed prosthetic restoration against the tooth to be restored
  • Presence of adjacent teeth next to the tooth to be restored

Exclusion Criteria:

  • Fractured or cracked teeth
  • Patients with temporomandibular joint disorders
  • Patients with bruxism (teeth grinding)
  • Molar teeth without an opposing tooth or fixed prosthetic restoration
  • Molar teeth without adjacent teeth
  • Vital teeth
  • Patients with a history of allergy to the components of the resins

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Prevention
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: Saremco print resin
Device: Saremco print resin
The teeth were restored with Saremco print resin via Asiga Max printer according to the manufacturer's instructions.
Active Comparator: Varseosmile Crownplus resin
Device: Varseosmile Crownplus resin
The teeth were restored with Varseosmile Crownplus resin via Asiga Max printer according to the manufacturer's instructions.
Active Comparator: Varseosmile TriniQ resin
Device: Varseosmile TriniQ resin
The teeth were restored with Varseosmile TriniQ resin via Asiga MAx printer according to the manufacturer' instructions

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Clinical performance
Time Frame: Baseline- 6 months-12 months

The clinical evaluation of restorations bonded to teeth will be performed at baseline, at 6 months, and at 12 months using the World Dental Federation (FDI) criteria which are divided into 3 main categories as functional, biological and esthetic properties. Each property is typically scored on a 1 to 5 scale:

  1. - Clinically excellent
  2. - Clinically good
  3. - Clinically sufficient
  4. - Clinically insufficient
  5. - Clinically poor
Baseline- 6 months-12 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Mersin University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

June 18, 2025

Primary Completion (Estimated)

December 18, 2026

Study Completion (Estimated)

June 18, 2027

Study Registration Dates

First Submitted

April 18, 2025

First Submitted That Met QC Criteria

April 28, 2025

First Posted (Actual)

May 7, 2025

Study Record Updates

Last Update Posted (Estimated)

September 10, 2025

Last Update Submitted That Met QC Criteria

September 9, 2025

Last Verified

September 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2025/364

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Sharing Supporting Information Type

  • STUDY_PROTOCOL
  • SAP
  • ICF
  • ANALYTIC_CODE
  • CSR

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Endodontically-Treated Teeth

Clinical Trials on Saremco print resin

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Vietnam

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

3
Subscribe