Correlation Between Coagulation Profiles And Injury Severity In Road Traffic Accidents Patients at Dera Ismail Khan

June 26, 2025 updated by: Muhammad Naveed Babur, Superior University
Trauma-induced coagulopathy (TIC), also known as acute traumatic coagulopathy (ATC), is a common condition in patients with severe trauma, particularly in road traffic accident (RTA) victims. Coagulopathy is often associated with high mortality rates and poor outcomes in trauma patients.

Study Overview

Status

Active, not recruiting

Conditions

Intervention / Treatment

Detailed Description

The study explores the correlation between coagulation profiles and the severity of injuries in patients admitted to a tertiary care hospital following RTAs.

Study Type

Observational

Enrollment (Actual)

230

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Pakistan
    • Khyber Pakhtunkhwa
      • Dera Ismāīl Khān, Khyber Pakhtunkhwa, Pakistan
        • Mufti Mehmood Memorial Teaching Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

To assess the correlation between coagulation profiles and injury severity in trauma patients, with a focus on the prevalence of trauma-induced coagulopathy (TIC) in road traffic accident (RTA) cases at a tertiary care hospital in Dera Ismail Khan.

Methods: A cross-sectional observational study will be conducted in the Accident & Emergency (A&E) Department and Trauma Center of DHQ Hospital, Dera Ismail Khan. The study population includes patients aged 18 years and above, with moderate to severe injuries (Injury Severity Score ≥ 15),

Description

Inclusion Criteria:

  • Patients with moderate to severe injuries (Injury Severity Score>15).
  • All Patients will be admitted in Accident and Emergency Center after the accident.

Exclusion Criteria:

  • Patients with Mild injury and score <15.
  • Patients with pre-existing coagulation disorders (e.g., hemophilia).
  • Patients on anticoagulant therapy prior to admission.
  • Patients with incomplete medical records or insufficient blood samples.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Self Admisnistred questioner
Time Frame: 12 Months
A Self Admisnistred questioner is used to collect the data and details of the accident
12 Months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Superior University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

March 17, 2025

Primary Completion (Estimated)

September 1, 2025

Study Completion (Estimated)

March 1, 2026

Study Registration Dates

First Submitted

June 26, 2025

First Submitted That Met QC Criteria

June 26, 2025

First Posted (Actual)

July 4, 2025

Study Record Updates

Last Update Posted (Actual)

July 4, 2025

Last Update Submitted That Met QC Criteria

June 26, 2025

Last Verified

June 1, 2025

More Information

Terms related to this study

Other Study ID Numbers

  • MSAHSW/Batch-Fall23/922

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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