Effects of CHRIST Among Children With Spastic CP

November 17, 2025 updated by: Riphah International University

Effects of Comprehensive Hand Intense Strength Training on In Hand Manipulation and Grip Strength Among Children With Spastic Cerebral Palsy

This Quasi experimental study investigates the effects of CHRIST on In Hand Manipulation and Grip Strength amonfg children with Spastic Cerebral Palsy. The study involves 14 children from 6-12 years of age, and will be given intervention for 10 weeks period.

Key performance outcomes- In Hand Manipulation and Grip Strength will be assessed both before and after the intervention. This study aims to address this gap by evaluating the effects of the CHRIST on IHM and grip strength in children diagnosed with spastic cerebral palsy. The hypothesis is that integrating strength training with high repetition, functionally relevant tasks yields greater and more practical gains than strength training or conventional therapy alone. Data will be analyzed through SPSS version 27.0

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Detailed Description

This Quasi Experimental study investigates the effects of CHRIST on In Hand Manipulation and Grip Strength in children with Spastic Cerebral Palsy. CHRIST was designed to enhance the motor ability of children. The efficacy of this program will be investigated through a Quasi Experimental study. Data will be collected from special schools and rehabilitation centers having children with spastic cerebral palsy. The intervention CHRIST will be given thrice a week for forty minutes. The study will be completed in 10 weeks after approval of the synopsis. The study will include 14 children, male and female. Inclusion criteria for the study will include patients diagnosed with spastic CP. Data will be collected from children aged 6 to 12 years old. IHM will be measured by Melbourne Assessment 2 scale (MA2). Grip Strength will be measured by dynamometer. IHM & Grip Strength will be assessed both before and after the intervention.This study aims to address this gap by evaluating the effects of CHRIST on IHM and grip strength in children diagnosed with spastic cerebral palsy. The hypothesis is that integrating strength training with high repetition, functionally relevant tasks yields greater and more practical gains than strength training or conventional therapy alone. Data will be analyzed through SPSS version 27.0

Study Type

Interventional

Enrollment (Estimated)

14

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Study Locations

  • Pakistan
    • Punjab Province
      • Lahore, Punjab Province, Pakistan, 5400

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Children Diagnosed with hemiplegic spastic cerebral palsy.
  • Age 6-12 years.
  • Capable of following commands regarding hand use and testing.
  • Capable of communicating needs.
  • Parents or caregivers willing to provide informed consent and participate in the study.
  • No contraindications to moderate physical activity.
  • Able to lift the more affected arm 15 cm above a table surface and grasp light objects

Exclusion Criteria:

  • Children with musculoskeletal system injuries, including upper limb fractures or contractures, as well as those who had received medications affecting muscle strength or spasticity, were excluded from the study.
  • Orthopedic surgery involving the more affected hand within the past 6 months.
  • Children with Cardiovascular disease.
  • Lack of cooperation with instructions or other behavioral challenges that prevent effective delivery of intensive therapy.
  • Visual impairments that may hinder active participation.
  • Seizure or family history of seizure disorders

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Other
  • Allocation: N/A
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: The intervention will be comprehensive hand repetitive intense strength training
CHRIST, is a treadmill-based training with body weight supported by the upper limbs. There will be a session of 40 minutes, which includes 3 sets (10 minutes exercise with 3 minutes rest period per set), three times a week, over a 10 week period. By maintaining the posture of the quadruped, the abdomen and weight of the lower limb will be supported by using a support board under the abdomen. The speed of the treadmill for the upper limbs will be 0.3-1.2 km/h. Results will be evaluated by MA2 and dynamometer.
Other: CHRIST
CHRIST, is a treadmill-based training with body weight supported by the upper limbs. There will be a session of 40 minutes, which includes 3 sets (10 minutes exercise with 3 minutes rest period per set), three times a week, over a 10 week period. By maintaining the posture of the quadruped, the abdomen and weight of the lower limb will be supported by using a support board under the abdomen. The speed of the treadmill for the upper limbs will be 0.3-1.2 km/h.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Jamma Dynamometer
Time Frame: Baseline, 1st week and 10th week
Grip strength will be measured by Jammar Dynamometer. The hand-held dynamometer are reliable measurement instruments to measure muscle strength of the arm and hand in children with unilateral spastic cerebral palsy, aged 7 12 years
Baseline, 1st week and 10th week

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Melbourne assessment 2 (MA2)
Time Frame: Baseline, 1st week and 10th week
Melbourne Assessment 2 (MA2) will be used to assess in-hand manipulation before and after the intervention (CHRIST) to evaluate the impact. MA2 is a reliable and valid tool for assessment of upper limb in children with CP.
Baseline, 1st week and 10th week

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Riphah International University

Investigators

  • Principal Investigator: FAIRY ALI, MSPT, Riphah International University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

October 22, 2025

Primary Completion (Estimated)

June 2, 2026

Study Completion (Estimated)

June 16, 2026

Study Registration Dates

First Submitted

November 17, 2025

First Submitted That Met QC Criteria

November 17, 2025

First Posted (Actual)

November 24, 2025

Study Record Updates

Last Update Posted (Actual)

November 24, 2025

Last Update Submitted That Met QC Criteria

November 17, 2025

Last Verified

November 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • REC/RCR&AHS/FAIRY ALI

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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