Wear Experience With Daily Disposable Contact Lenses for Astigmatism Over a Long-Wear Day

The purpose of this study to assess the wear experience of people who have astigmatism when wearing a daily disposable contact lens for astigmatism over long days of wear.

Study Overview

• Status: Recruiting
• Conditions: Astigmatism
• Intervention / Treatment: Device: Daily disposable contact lenses for astigmatism

• Study Type: Interventional
• Enrollment (Estimated): 40
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Study Coordinators; Phone Number: 614-292-8858; Email: OPT-EyeStudies@osu.edu

Study Locations

• United States
  • Ohio
    • Columbus, Ohio, United States, 43210
      • Recruiting
      • The Ohio State University College of Optometry
      • Contact: Emma Grant; Phone Number: 614-292-8858; Email: OPT-EyeStudies@osu.edu
      • Contact: Emily Wagner; Phone Number: 614-292-8858; Email: OPT-EyeStudies@osu.edu

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• Current soft toric contact lens wearer with long hours of wear
• Willing to follow the contact lens wearing schedule required by the study
• Vision 20/25 or better with current soft toric contact lenses
• Self-report completion of a comprehensive eye examination in the past two years

Exclusion Criteria:

• Have a history of corneal ocular surgery
• Have current ocular inflammation or infection as assessed by the study investigator who will complete the study
• Are past rigid contact lens wearers
• Have a history of being diagnosed with dry eye or ocular allergies
• Have known systemic health conditions that are thought to alter tear film physiology
• Have a history of viral eye disease
• Have a history of ocular surgery
• Have a history of severe ocular trauma
• Have a history of corneal dystrophies or degenerations
• Have active ocular infection or inflammation
• Are currently using isotretinoin-derivatives or ocular medications
• Are pregnant or breast feeding

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Other
• Allocation: N/A
• Interventional Model: Single Group Assignment
• Masking: None (Open Label)

Number of Arms

1

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Other: Contact Lens Wear; All participants will be fit with the study contact lenses for astigmatism	Device: Daily disposable contact lenses for astigmatism; All participants will be fit with the study lenses; Other Names: Dailies Total1 for Astigmatism

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Comfort	Proportion of participants with positive Visual Analog Scale (VAS, >50 on a 0-100 scale)	Measured over 16 hours of wear

Collaborators and Investigators

• Sponsor: Ohio State University
• Collaborators: Alcon Research

Study record dates

Study Major Dates

• Study Start (Actual): March 4, 2026
• Primary Completion (Estimated): June 30, 2026
• Study Completion (Estimated): June 30, 2026

Study Registration Dates

• First Submitted: December 23, 2025
• First Submitted That Met QC Criteria: December 23, 2025
• First Posted (Actual): December 26, 2025

Study Record Updates

• Last Update Posted (Actual): March 25, 2026
• Last Update Submitted That Met QC Criteria: March 23, 2026
• Last Verified: March 1, 2026

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Eye Diseases; Refractive Errors; Astigmatism
• Other Study ID Numbers: 20252462

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: Yes
• product manufactured in and exported from the U.S.: Yes