the Effect of Virtual Reality Exercise on Selected Electrolytes Levels in Intradialytic Patients (VRE)

this study will be conducted to investigate the effect of Intra-Dialysis virtual reality exercise on selected electrolytes balance in patients with end stage renal disease.

Study Overview

• Status: Not yet recruiting
• Conditions: Chronic Kidney Diseases
• Intervention / Treatment: Other: Virtual Reality Exercise; Other: standard care

Detailed Description

Chronic Kidney Disease (CKD) is a progressive condition that often leads to end-stage renal disease, requiring dialysis. Patients undergoing hemodialysis frequently experience physical inactivity and electrolyte imbalances, which can adversely affect their health outcomes. Regular physical activity is crucial for maintaining muscle strength and physical function in CKD patients.Electrolytes play vital roles in various physiological functions, including muscle contraction, nerve transmission, and fluid balance. In end stage renal disease patients, imbalances can lead to serious complications, including: hyperkalemia, Hyponatremia, and hypocalcemia.VR has been employed in medicine to assist patients in recovering their motor and cognitive abilities. It has proven effective in enhancing physical functions such as posture, balance, and motor skills. When combined with physical exercise, VR has been shown to improve the functional abilities and quality of life of hemodialysis patients. For those with end stage renal disease patients, who experience discomfort during hemodialysis, VR offers a distraction that can reduce the perception of pain, fatigue, nausea, lightheadedness, and headaches, thereby facilitating smoother exercise continuity and enhancing overall adherence to rehabilitation activities. so this study will be conducted to assess the effect of Intra-Dialysis Virtual Reality Exercise on Selected Electrolytes Balance in Patients with End Stage Renal Disease

• Study Type: Interventional
• Enrollment (Estimated): 40
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: sarah mohamed, master; Phone Number: 01149967455; Email: sarahalsyed88@gmail.com

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

• Patients are diagnosed with end stage renal disease on regular dialysis.
• Their ages will be arranged from 20-40 years old.
• All patients are under medical control.
• Patients on regular dialysis more than 3 months.

Exclusion Criteria:

• Visual impairment.
• Severe cognitive impairment.
• Recent major surgery.
• Patients with sever musculoskeletal problems.
• Severe cardiovascular disease limiting exercise.
• Patients with Hemoglobin drop less than 9 g/dl

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Virtual Reality Exercise; Twenty patients will receive virtual reality exercise during dialysis sessions three times per weeks for 3 months (30 minutes of guided VR exercise).	Other: Virtual Reality Exercise; the patients will receive 30 minutes virtual reality exercise; (5 minutes warm Up stretching exercise - 20 minutes cycling exercise -5 minutes cool down stretching exercise) plus standard care; Other: standard care; the patients will receive standard care in the form of medical care
Active Comparator: standard care; Twenty patients will receive standard care during dialysis sessions three times per weeks for 3 months.	Other: standard care; the patients will receive standard care in the form of medical care

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Serum Electrolyte Levels	Measurements the level of sodium, potassium, calcium and phosphorus by venous blood sample. the normal value for Sodium: 135-145 mEq/L ,Potassium: 3.5-5.0 mEq/L, Calcium: 8.5-10.2 mg/dL, and Phosphorus: 2.5-4.5 mg/dL	up to three months

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
blood pressure	A sphygmomanometer will be used to assess blood pressure with normal range 120/80	up to three months
oxygen saturation levels	A pulse oximeter will be used to assess oxygen saturation level. 95-100% considered normal for healthy individuals	up to three months
functional exercise capacity	6-Minute Walk Test will be used to assess functional exercises capacity	up to three months
exercise intensity	The Rated Perceived Exertion (RPE) Scale will be used to assess exercise intensity. it is a subjective 6-20 scale measuring exercise intensity, where 6 is no effort (rest) and 20 is maximum effort.	up to three months

Collaborators and Investigators

• Sponsor: Cairo University

Study record dates

Study Major Dates

• Study Start (Estimated): January 1, 2026
• Primary Completion (Estimated): June 1, 2026
• Study Completion (Estimated): June 1, 2026

Study Registration Dates

• First Submitted: December 19, 2025
• First Submitted That Met QC Criteria: December 19, 2025
• First Posted (Actual): January 5, 2026

Study Record Updates

• Last Update Posted (Actual): January 5, 2026
• Last Update Submitted That Met QC Criteria: December 19, 2025
• Last Verified: December 1, 2025

More Information

Terms related to this study

• Keywords: Virtual Reality Exercise; Selected Electrolytes Levels; Intradialytic Patients
• Additional Relevant MeSH Terms: Urogenital Diseases; Pathologic Processes; Male Urogenital Diseases; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Chronic Disease; Disease Attributes; Renal Insufficiency; Pathological Conditions, Signs and Symptoms; Renal Insufficiency, Chronic; Health Services Administration; Health Care Quality, Access, and Evaluation; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Quality of Health Care; Quality Indicators, Health Care; Exercise; Standard of Care; Exergaming
• Other Study ID Numbers: P.T.REC/012/005982

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No