Effect of Patellar Denervation on Post-operative Knee Pain and Knee Function in Total Knee Arthroplasty (PD)

January 7, 2026 updated by: Queen Savang Vadhana Memorial Hospital, Thailand

Effect of Patellar Denervation on Post-operative Knee Pain and Knee Function in Total Knee Arthroplasty: A Randomized Controlled Trial

This study is a double-blind randomized controlled trial aiming to investigate the effects of patellar denervation using electrocautery on postoperative knee pain and knee function in patients undergoing primary total knee arthroplasty (TKA) without patellar resurfacing.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

This study is a prospective, double-blind randomized controlled trial conducted at Queen Savang Vadhana Memorial Hospital between 2023 and 2025. The aim of the study is to assess the effect of patellar denervation using electrocautery on postoperative knee pain and knee function in patients undergoing primary total knee arthroplasty (TKA) without patellar resurfacing.

Sixty-four patients were enrolled and randomly assigned to either the patellar denervation group (PD) or the non-denervation group (NPD), with 32 participants in each group.

Study Type

Interventional

Enrollment (Actual)

64

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Thailand
    • Changwat Chon Buri
      • Chon Buri, Changwat Chon Buri, Thailand, 20110
        • Chalathorn Kulthonchalanan

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Age 55-85 years old
  • Knee osteoarthritis
  • Plan for total knee arthroplasty after failed conservative treatment for at least 3 months

Exclusion Criteria:

  • Previous history of trauma, fracture or open surgery on the same knee
  • Inflammatory arthritis or Crystal-induced arthritis
  • Patellar instability or isolated patellofemoral osteoarthritis
  • Unable to answer questionnaire
  • Cannot tolerate surgery due to medical comorbidities

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Triple

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Patellar Denervation
Procedure: Patellar Denervation
Electrocautery patella circumferentially during total knee arthroplasty
No Intervention: Non-Patellar Denervation

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Visual analog scale score for knee pain
Time Frame: 2 weeks, 6 weeks, 3 months, 6 months, and 12 months
2 weeks, 6 weeks, 3 months, 6 months, and 12 months

Secondary Outcome Measures

Outcome Measure
Time Frame
Kujala score
Time Frame: 3 months, 1 year
3 months, 1 year
Knee Society score
Time Frame: 3 months, 1 year
3 months, 1 year
Timed up and go test
Time Frame: 3 months, 1 year
3 months, 1 year

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Queen Savang Vadhana Memorial Hospital, Thailand

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

August 8, 2023

Primary Completion (Actual)

June 21, 2025

Study Completion (Actual)

June 21, 2025

Study Registration Dates

First Submitted

December 25, 2025

First Submitted That Met QC Criteria

January 7, 2026

First Posted (Actual)

January 15, 2026

Study Record Updates

Last Update Posted (Actual)

January 15, 2026

Last Update Submitted That Met QC Criteria

January 7, 2026

Last Verified

January 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 021/2566

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

IPD Plan Description

Data was save in form of Google sheet

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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