Long COVID Diagnostic Reactivity Assesment Test (EAV-LONGCOVID)

January 7, 2026 updated by: Oncology Center,Ministry Of Heath,Uzbekistan

Development of a Personalized Alternative Non-invasive Rapid Diagnostic Test for SARS-CoV-2 in Patients With Long COVID

This study is a diagnostic clinical investigation designed to evaluate bioelectrical response patterns assessed by electro-acupuncture-based medicament testing.

The method is used to identify individual bioelectrical reactivity associated with the presence and persistence of pathological factors and to assess patient-specific responses to tested medicinal substances.

The study involves a single-session, non-invasive diagnostic procedure without administration of pharmacological treatment. The primary objective is the methodological evaluation of the diagnostic approach and the characterization of the detected bioelectrical response patterns in the studied population.

Study Overview

Status

Enrolling by invitation

Conditions

Intervention / Treatment

Detailed Description

This study is a diagnostic clinical investigation designed to evaluate bioelectrical response patterns assessed by electro-acupuncture-based medicament testing.

The method is used to identify individual bioelectrical reactivity associated with the presence and persistence of pathological factors and to assess patient-specific responses to tested medicinal substances.

The study involves a single-session, non-invasive diagnostic procedure without pharmacological treatment. The primary objective is the methodological evaluation of the diagnostic approach and the characterization of the detected bioelectrical response patterns in the studied population.

Study Type

Interventional

Enrollment (Estimated)

50

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Uzbekistan
      • Tashkent, Uzbekistan, 100194
        • Research Institute of Virology

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Age 18 years or older
  • History of confirmed SARS-CoV-2 infection
  • Persistent symptoms consistent with Long COVID lasting ≥12 weeks after acute infection
  • Ability to provide informed consent
  • Willingness to undergo non-invasive bioelectrical diagnostic assessment

Exclusion Criteria:

  • Acute infectious disease at the time of enrollment
  • Severe uncontrolled medical or psychiatric conditions that may interfere with diagnostic assessment
  • Implanted electronic medical devices (e.g., pacemaker)
  • Pregnancy or breastfeeding
  • Inability to comply with study procedures

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Diagnostic
  • Allocation: N/A
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Diagnostic Assesment Arm
This single-arm study includes participants undergoing a non-invasive electrodiagnostic assessment to evaluate bioelectrical response patterns associated with viral antigen persistence. No therapeutic intervention is administered.
Diagnostic test: Electrodiagnostic Bioelectrical Assessment
A non-invasive diagnostic procedure performed during a single session to assess bioelectrical response patterns associated with viral antigen persistence. Measurements are obtained using standardized bioelectrical assessment techniques without administration of any therapeutic agents or interventions.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Number of Participants With Bioelectrical Response Patterns Consistent With Viral Persistence
Time Frame: At enrollment (single diagnostic session)
Non-invasive diagnostic assessment using electroacupuncture-based medicament testing to identify bioelectrical response patterns consistent with viral antigen persistence in participants with post-viral conditions.
At enrollment (single diagnostic session)

Secondary Outcome Measures

Outcome Measure
Time Frame
Distribution of Bioelectrical Reactivity Patterns During Medicament Testing
Time Frame: Baseline(Day 1)
Baseline(Day 1)

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Oncology Center,Ministry Of Heath,Uzbekistan

Investigators

  • Principal Investigator: Naylya Djumaeva, MD,PhD, Reseacrh Institute of Virology

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

December 5, 2025

Primary Completion (Estimated)

December 30, 2026

Study Completion (Estimated)

January 1, 2027

Study Registration Dates

First Submitted

December 24, 2025

First Submitted That Met QC Criteria

January 7, 2026

First Posted (Actual)

January 15, 2026

Study Record Updates

Last Update Posted (Actual)

January 15, 2026

Last Update Submitted That Met QC Criteria

January 7, 2026

Last Verified

December 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 9/36-2216

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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