The Effect of Sealer Type and Obturation Technique on Postoperative Pain (pain)

January 27, 2026 updated by: Jordan University of Science and Technology

The Effect of Sealer Type and Obturation Technique on Postoperative Pain of Root Canal Treated Teeth

Postoperative pain is an important consideration in endodontic treatment, and its incidence may be influenced by both obturation technique and sealer type. This study focused on molars to minimize anatomical variability and provide a consistent assessment of pain associated with different endodontic protocols.

This study aimed to evaluate the incidence and level of postoperative pain in molars treated with root canal therapy, in relation to the type of sealer and obturation technique used.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

One hundred and twenty patients (aged 18-60 years; 63 males, 57 females) requiring root canal treatment of mandibular or maxillary molars will be included. Only teeth with necrotic pulp and asymptomatic apical periodontitis or previously extirpated pulp are considered. Patients will be randomly assigned to one of four groups (30 patients each): Group A-AH Plus resin sealer with cold lateral compaction (AH-CLC); Group B-AH Plus with warm vertical compaction (AH-WVC); Group C-TotalFill bioceramic sealer with single-cone technique (TF-SC); Group D-TotalFill HiFlow with warm vertical compaction (TF-WVC). Postoperative pain will be self-recorded using the Visual Analog Scale (VAS) and Verbal Rating Scale (VRS) at 6 hours, 1 day, 2 days, 3 days, and 1 week after treatment. Completed forms will be collected when patients returned for permanent coronal restoration. Analgesic use was also recorded. Data will analyzed using one way ANOVA and Chi square tests.

Study Type

Interventional

Enrollment (Actual)

120

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Jordan
      • Irbid, Jordan, 221000
        • Jordan University of Science and Technology

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  1. both male and female patients within
  2. The age of 18-60 years old who required root canal treatment
  3. Either mandibular or maxillary molars with the diagnosis of either; necrotic pulp with asymptomatic apical periodontitis,
  4. Teeth with pulp extirpated ( previously initiated root canal treatment) regardless of the periapical status

Exclusion Criteria:

  1. Teeth diagnosed with irreversible pulpitis;
  2. Teeth with intracanal abberations or mishaps such as perforations, transportation, severe ledging , broken instruments, apical resorption or open apices;
  3. Teeth requiring posts;
  4. Any patient on long term steroid or any other medical condition that requires long term analgesic.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: AH Plus resin sealer with cold lateral compaction
Obturation using cold lateral condensation and resin sealer
Procedure: Obturation of root canals
filling of root canal using different materials of resin based or bioceramic based and cold lateral condensation or warm vertical condenstion techniques
Other Names:
  • Root canal filling with bioceramic sealers
Active Comparator: AH Plus with warm vertical compaction
Obturation using warm vertical compaction and resin sealer
Procedure: Obturation of root canals
filling of root canal using different materials of resin based or bioceramic based and cold lateral condensation or warm vertical condenstion techniques
Other Names:
  • Root canal filling with bioceramic sealers
Active Comparator: TotalFill bioceramic sealer with single-cone technique
Obturation with single cone and bioceramic sealer
Procedure: Obturation of root canals
filling of root canal using different materials of resin based or bioceramic based and cold lateral condensation or warm vertical condenstion techniques
Other Names:
  • Root canal filling with bioceramic sealers
Active Comparator: TotalFill HiFlow with warm vertical compaction
Obturation with warm vertical compaction and bioceramic sealer
Procedure: Obturation of root canals
filling of root canal using different materials of resin based or bioceramic based and cold lateral condensation or warm vertical condenstion techniques
Other Names:
  • Root canal filling with bioceramic sealers

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Pain level after obturation of root canals
Time Frame: 6 hours, 1 day, 2 days, 3 days and 1 week
The level of pain the patient will experience after obturation of the teeth using a visual analogue scale and a numerical scale from 0-10. Zero is the minimum and 10 is the maximum. The higher the score the worse it is, the best technique will have low scores of pain
6 hours, 1 day, 2 days, 3 days and 1 week

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Jordan University of Science and Technology

Investigators

  • Study Chair: Ahmad Alhiyasat, PhD, Jordan University of Science and Technology

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

October 7, 2022

Primary Completion (Actual)

July 28, 2023

Study Completion (Actual)

October 2, 2023

Study Registration Dates

First Submitted

January 15, 2026

First Submitted That Met QC Criteria

January 27, 2026

First Posted (Actual)

February 4, 2026

Study Record Updates

Last Update Posted (Actual)

February 4, 2026

Last Update Submitted That Met QC Criteria

January 27, 2026

Last Verified

January 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 313/2021
  • Deanship of Research (Other Identifier: Jordan University of Science and Technology)

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

Data will be shared upon reasonable request from the study principal

IPD Sharing Time Frame

After publication of the data and up to 5 years

IPD Sharing Access Criteria

Request via email to the study chair

IPD Sharing Supporting Information Type

  • STUDY_PROTOCOL

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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