- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07437092
Facilitating Psychological Closure and Emotional Change Through Mindfulness Meditation
Mindful Recollection: Attending to the Present Before Resolving the Past
The goal of this clinical trial is to learn if mindfulness meditation can improve closure and emotion towards unresolved memories in an undergraduate student population. This will be tested through a brief, novel intervention called Mindful Recollection, where participants transition immediately from mindfulness meditation into the recollection of an unresolved memory. The secondary aim of the study is to investigate the mechanisms of change underlying Mindful Recollection. Overall then, the main questions this study aims to answer are:
- Does mindful recollection reduce negative emotions associated with unresolved event memories?
- Can increases in acceptance, decentering, and reappraisal account for the observed effects of mindful recollection on negative emotion?
- Does mindful recollection facilitate closure towards unresolved event memories?
- Can increases in acceptance, decentering, and reappraisal account for the observed effects of mindful recollection on closure?
Researchers will compare the Mindful Recollection intervention to a mind-wandering control task to see if mindfulness meditation uniquely produces positive changes in emotion and closure above and beyond placebo. Mindful Recollection will involve a 13-minute audio-guided mindfulness meditation followed immediately by 2 minutes of memory recollection. The control task will involve 13-minutes of audio-guided mind-wandering followed immediately by 2 minutes of memory recollection.
Participants will:
- Complete pretest measures of emotion and closure towards an unresolved event memory.
- Engage in either the Mindful Recollection intervention or the placebo control task after a 24-72 hour delay.
- Complete post-test measures of emotion and closure towards the same unresolved event memory.
Study Overview
Status
Conditions
Intervention / Treatment
Study Type
Enrollment (Estimated)
Phase
- Not Applicable
Contacts and Locations
Study Contact
- Name: Anas Alsayed Hasan
- Phone Number: 647-224-1595
- Email: alsayed4@uwindsor.ca
Study Locations
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Ontario
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Windsor, Ontario, Canada, N9B 3P4
- University of Windsor
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Contact:
- Anas Alsayed Hasan
- Phone Number: 647-224-1595
- Email: alsayed4@uwindsor.ca
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Adult
- Older Adult
Accepts Healthy Volunteers
Description
Inclusion Criteria:
- Ability to hear and understand spoken instructions clearly; English language proficiency
Exclusion Criteria:
- Trauma history/Dissociative tendencies
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: Mindful Recollection
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Mindful Recollection consists of a 15-minute audio-guided task (13 minutes of guided meditation followed immediately by 2 minutes of unresolved event recollection).
The 13-minute guided meditation is intended to facilitate a broad mindful awareness by working through sensations of the breath, body, and mind (in that respective order), eventually coming together in a practice of open monitoring - the non-selective observation of any and all aspects of experience.
The 2-minute recollection period will have participants transition from meditating to recalling and reflecting on an unresolved memory they identified during the pretest period (approximately 24-72 hours prior).
|
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Sham Comparator: Mind-Wandering
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The mind-wandering control task consists of a 15-minute audio-guided task (13 minutes of mind-wandering followed immediately by 2 minutes of unresolved event recollection).
Mind-wandering is a common sham mindfulness technique that repeatedly prompts participants to let their thoughts flow freely, thinking about whatever comes to mind.
This exposes participants to the same procedure (i.e., listening to a 13-minute audio-recording) without receiving guided mindful meditation instructions.
Thus, this condition will guide participants to have a typical mental experience of thinking freely about whatever comes to mind, without developing a mindful awareness of their internal experience.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Pre- to Post-Test Changes in Psychological Closure using the Closure and Resolution Scale (CRS)
Time Frame: Baseline (24-72 hours prior to the intervention) and post-test (immediately after intervention)
|
Items are rated on a 7-point Likert scale (1 = Completely disagree, 7 = Completely agree), with higher scores reflecting greater levels of closure and resolution.
|
Baseline (24-72 hours prior to the intervention) and post-test (immediately after intervention)
|
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Pre- to Post-Test Changes in Negative Emotion using the Positive and Negative Affect Schedule (PANAS)
Time Frame: Baseline (24-72 hours prior to the intervention) and post-test (immediately after intervention)
|
Items are rated on a 5-point Likert scale (1 = Not at all, 5 = Extremely), with higher scores reflecting a stronger endorsement of that emotional experience.
|
Baseline (24-72 hours prior to the intervention) and post-test (immediately after intervention)
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Experiential Acceptance Towards Thoughts and Emotions
Time Frame: Immediately after the intervention (post-test)
|
Using the acceptance subscale of The Southampton Experiential Avoidance and Acceptance Scale. Items are rated on a 7-point Likert scale (1 = Strongly disagree, 7 = Strongly agree), with higher scores indicating greater levels of openness towards internal experience. |
Immediately after the intervention (post-test)
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|
Reappraisal
Time Frame: Immediately after the intervention (post-test)
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Using the Regulation of Emotion Systems Survey.
Items are rated on a 5-point Likert scale (1 = Strongly disagree, 5 = Strongly agree), with higher scores indicating greater engagement in reappraisal during the assigned task.
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Immediately after the intervention (post-test)
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State Decentering
Time Frame: Immediately after the intervention (post-test)
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Using the Metacognitive Processes of Decentering-state scale.
Items are rated on an 11-point Likert scale (0 = Not at all, 10 = Very much), with higher scores reflecting greater levels of state decentering (i.e., being aware of, disidentified with, and nonreactive to thoughts and emotions).
|
Immediately after the intervention (post-test)
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Other Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Memory Characteristics
Time Frame: Immediately after the intervention (post-test)
|
Using the Memory Experience Questionnaire Short-Form. Measures distinct qualities of autobiographical memory (e.g., coherence, vividness, visual perspective). Items are rated on a 5-point Likert scale (1 = Strongly disagree, 5 = Strongly agree), with higher scores indicating greater endorsement of a given memory characteristic. |
Immediately after the intervention (post-test)
|
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State Mindfulness (Manipulation Check)
Time Frame: Immediately after the intervention (post-test)
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Using the State Mindfulness Scale. Administered as a manipulation check to measure participants' reports of mindful states during the assigned tasks. Items are rated on a 5-point Likert scale (1 = Not at all, 5 = Very well), with higher scores indicating greater states of mindfulness. |
Immediately after the intervention (post-test)
|
Collaborators and Investigators
Sponsor
Publications and helpful links
General Publications
- Watson D, Clark LA, Tellegen A. Development and validation of brief measures of positive and negative affect: the PANAS scales. J Pers Soc Psychol. 1988 Jun;54(6):1063-70. doi: 10.1037//0022-3514.54.6.1063.
- Tanay G, Bernstein A. State Mindfulness Scale (SMS): development and initial validation. Psychol Assess. 2013 Dec;25(4):1286-99. doi: 10.1037/a0034044. Epub 2013 Sep 23.
- Luchetti M, Sutin AR. Measuring the phenomenology of autobiographical memory: A short form of the Memory Experiences Questionnaire. Memory. 2016;24(5):592-602. doi: 10.1080/09658211.2015.1031679. Epub 2015 Apr 20.
- De France, K., & Hollenstein, T. (2017). Assessing emotion regulation repertoires: The Regulation of Emotion Systems Survey. Personality and Individual Differences, 119, 204-215. https://doi.org/10.1016/j.paid.2017.07.018
- McAndrews, Z., Hart, C. M., & Stopa, L. (2024). Development of the Southampton Experiential Avoidance and Acceptance Scale (SEAAS). Journal of Contextual Behavioral Science, 33, 100822-. https://doi.org/10.1016/j.jcbs.2024.100822
- Hanley AW, Bernstein A, Nakamura Y, Hadash Y, Rojas J, Tennant KE, Jensen RL, Garland EL. The Metacognitive Processes of Decentering Scale: Development and initial validation of trait and state versions. Psychol Assess. 2020 Oct;32(10):956-971. doi: 10.1037/pas0000931. Epub 2020 Jul 23.
- Boucher CM, Scoboria A, Soucie K, Pascual-Leone A. Development and validation of the Closure and Resolution Scale (CRS). Memory. 2025 Feb;33(2):205-222. doi: 10.1080/09658211.2024.2427666. Epub 2024 Nov 19.
Study record dates
Study Major Dates
Study Start (Estimated)
Primary Completion (Estimated)
Study Completion (Estimated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- REB #25-135
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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