Central Venous Catheterization in Children: Jugulo-subclavian Venous Confluence Versus Internal Jugular Vein

March 6, 2026 updated by: Mehdi Trifa, Tunis University

The goal of this study was to compare ultrasound-guided central venous catheterization via the IJV to the JSVC using the supraclavicular approach in children. The main questions it aims to answer are:

  1. Are ultrasound-guided central venous catheterization via the internal jugular vein (IJV) and via the jugular-supraclavicular vein (JSVC) using the supraclavicular approach equivalent in terms of procedural efficacy (e.g., success rate, time to cannulation) in children?
  2. Are these two techniques comparable in terms of safety (e.g., complication rates, adverse events) in pediatric patients?

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

88

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Tunisia
      • Tunis, Tunisia
        • Bechir Hamza Children Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Children aged 1 month to 14 years, admitted to the pediatric intensive care unit of the anesthesiology and critical care department at Béchir Hamza Children's Hospital in Tunis, or scheduled for major elective surgery under general anesthesia requiring central venous catheter placement.

Exclusion Criteria:

  • Patients in whom ultrasound revealed a thrombotic formation in the vein.
  • Patients for whom the vein could not be adequately visualized on ultrasound

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Other
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Other: IVJ group
Group undergoing catheterization of the internal jugular vein using an out-of-plane technique
Procedure: central venous catheterization
ultrasound guided central venous catheterization in children
Other: JSVC group
Group undergoing catheterization of the jugulosubclavian confluent via the supraclavicular in-plane technique
Procedure: central venous catheterization
ultrasound guided central venous catheterization in children

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
first-attempt Success rate
Time Frame: From the day of randomization until radiographic confirmation of central venous catheter position, assessed up to 6 hours.
Obtaining blood reflux from the target vein on the first attempt
From the day of randomization until radiographic confirmation of central venous catheter position, assessed up to 6 hours.

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Tunis University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

December 17, 2023

Primary Completion (Actual)

April 30, 2025

Study Completion (Actual)

April 30, 2025

Study Registration Dates

First Submitted

February 9, 2026

First Submitted That Met QC Criteria

March 6, 2026

First Posted (Actual)

March 9, 2026

Study Record Updates

Last Update Posted (Actual)

March 9, 2026

Last Update Submitted That Met QC Criteria

March 6, 2026

Last Verified

July 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 072025

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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