The Effect of Mindfulness-Based Nursing Interventions Applied to Hemodialysis Patients on Psychological Well-Being and Treatment Adherence (Mindfulness)

March 12, 2026 updated by: Çiğdem Özdemir Eler, Baskent University
Chronic kidney disease (CKD) and its treatment with hemodialysis pose significant challenges to patients' psychological well-being and adherence to complex treatment regimens. This randomized controlled trial investigated the effects of nurse-led, mindfulness-based interventions on psychological well-being and treatment adherence in patients undergoing hemodialysis. Eighty patients from a single dialysis center in Türkiye were randomly assigned to either an intervention group (n = 40) receiving six weekly mindfulness sessions or a control group (n = 40) receiving routine care. Data were collected using the Mindful Attention Awareness Scale (MAAS), the Psychological Well-Being Scale (PWB), and the End-Stage Renal Disease Adherence Questionnaire (ESRD-AQ) at baseline and post-intervention. Mixed-design analyses revealed significant improvements in mindfulness, psychological well-being, and all subscales of treatment adherence-including hemodialysis attendance, medication adherence, fluid management, and dietary compliance-in the intervention group compared to the control group (p < 0.001). Moderate to large effect sizes (Cohen's d = 0.36-1.70) indicate clinically meaningful changes. Pearson correlation analysis demonstrated a positive association between psychological well-being and treatment adherence (r = 0.302, p < 0.01). These findings suggest that structured, nurse-delivered mindfulness programs can simultaneously enhance psychosocial outcomes and adherence behaviors in hemodialysis patients. Integrating mindfulness-based interventions into routine nursing care may provide dual benefits by promoting emotional well-being and supporting self-regulated adherence to treatment regimens. Future research should explore long-term effects, broader patient populations, and the interplay between mindfulness, self-efficacy, and other psychosocial variables to further inform patient-centered hemodialysis care.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

80

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

Voluntarily agreed to participate in the study

Receiving hemodialysis treatment for more than six months

Literate

18 years of age or older

Exclusion Criteria:

Diagnosed severe psychiatric disorder according to DSM-5 criteria

Auditory, visual, or cognitive impairments that could hinder participation in the educational process

Withdrawal Criteria:

Deterioration in general health status

Participant's request to discontinue participation

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Supportive Care
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: The Effect of Mindfulness-Based Nursing Interventions on Psychological Well-Being and Treatment Adhe
Behavioral intervention, Six weekly sessions of mindfulness-based nursing interventions delivered to hemodialysis patients to improve psychological well-being and treatment adherence.
Other: The intervention group received mindfulness-based nursing interventions for six weeks
The intervention group will receive mindfulness-based nursing interventions for 6 weeks, with one session per week averaging 1 hour.
Other Names:
  • mindfulness
No Intervention: The control group
The control group continued to receive routine dialysis treatment and did not receive any additional education during the study period. Data collection instruments were administered at baseline and at the end of the study. After completion of the research, the educational content was shared with control group participants upon request.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Mindful Attention Awareness Scale (MAAS)
Time Frame: 6 weeks from baseline
15-item scale scored on a 6-point Likert scale. Scores range from 15 to 90; higher scores indicate higher mindfulness.
6 weeks from baseline
Psychological Well-Being Scale (PWBS)
Time Frame: 6 weeks from baseline
8-item scale scored on a 7-point Likert scale. Total scores range from 8 to 56; higher scores indicate higher psychological well-being.
6 weeks from baseline
End-Stage Renal Disease Adherence Questionnaire (ESRD-AQ)
Time Frame: 6 weeks from baseline
9-item questionnaire assessing hemodialysis participation, medication adherence, fluid adherence, and diet adherence. Total scores range from 0 to 1200; higher scores indicate better adherence.
6 weeks from baseline

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Baskent University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

December 11, 2025

Primary Completion (Actual)

January 26, 2026

Study Completion (Actual)

January 26, 2026

Study Registration Dates

First Submitted

March 3, 2026

First Submitted That Met QC Criteria

March 12, 2026

First Posted (Actual)

March 13, 2026

Study Record Updates

Last Update Posted (Actual)

March 13, 2026

Last Update Submitted That Met QC Criteria

March 12, 2026

Last Verified

March 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • KA25/443

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

IPD Plan Description

Individual patient data will not be shared in order to protect participant privacy and data security. Although the data obtained within the scope of the study has been anonymized, it contains sensitive health information and will therefore only be used by the research team.

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Hemodialysis

Clinical Trials on The intervention group received mindfulness-based nursing interventions for six weeks

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Uzbekistan

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe