Comparison of Prosthetic Complications and Framework Misfit Among Different Cobalt-Chromium Framework Fabrication Techniques

March 18, 2026 updated by: Mansoura University

Comparison of Prosthetic Complications and Framework Misfit Among Different Cobalt-Chromium Framework Fabrication Techniques in Maxillary and Mandibular Full-Arch Implant-Supported Acrylic Screw-Retained Restorations: A Randomized Clinical Study

This randomized clinical study aimed to compare prosthetic complications and framework misfit associated with three different fabrication techniques of cobalt-chromium frameworks-conventional casting, CAD/CAM milling, and selective laser melting (SLM)-used in maxillary and mandibular full-arch implant-supported acrylic screw-retained restorations.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

27

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
    • Dakahlia Governorate
      • Al Mansurah, Dakahlia Governorate, Egypt, P.O.Box:35516
        • Mansoura University , Faculty Of Dentistry

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • • Six osseointegrated maxillary and six mandibular implants

    • No clinical or radiographic signs of implant failure
    • Good systemic health
    • Normal maxillomandibular relationship and acceptable oral hygiene

Exclusion Criteria:

  • • Implant failure

    • Unfavorable occlusal relationships
    • Poor compliance or inability to attend follow-up

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: Group I: Conventional cast Co-Cr framework
patients received maxillary and mandibular full-arch implant fixed prosthesis with conventional casting CO-CR framework
Device: Implant supported prosthesis
All patients received maxillary and mandibular six implants to support a metal acrylic screw retained full-arch prosthesis
Active Comparator: Group II: CAD/CAM milled Co-Cr framework
patients received maxillary and mandibular full-arch implant fixed prosthesis with milled CO-CR framework
Device: Implant supported prosthesis
All patients received maxillary and mandibular six implants to support a metal acrylic screw retained full-arch prosthesis
Active Comparator: Group III: Selective laser melting (SLM) Co-Cr framework
patients received maxillary and mandibular full-arch implant fixed prosthesis with a laser-melted CO-CR framework.
Device: Implant supported prosthesis
All patients received maxillary and mandibular six implants to support a metal acrylic screw retained full-arch prosthesis

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
the number of occurance of Prosthetic complications
Time Frame: after a year

The prosthetic complications were evaluated for the three different types of Co-Cr frameworks

The following prosthetic complications were evaluated:

  • abutment screw loosening
  • abutment screw fracture
  • prosthetic screw loosening
  • prosthetic screw fracture
  • acrylic teeth fracture (separation)
  • acrylic teeth wear (replacement)
  • co-cr framework fracture
after a year

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
the implant framework Passive fit
Time Frame: baseline
the passivity of the framework was evaluated digitally using 3D scan protocol
baseline

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Mansoura University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 18, 2024

Primary Completion (Actual)

November 6, 2024

Study Completion (Actual)

February 15, 2026

Study Registration Dates

First Submitted

February 23, 2026

First Submitted That Met QC Criteria

March 18, 2026

First Posted (Actual)

March 23, 2026

Study Record Updates

Last Update Posted (Actual)

March 23, 2026

Last Update Submitted That Met QC Criteria

March 18, 2026

Last Verified

December 1, 2023

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • A05012023RP

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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