Anthropometric Normalization in Inter-Individual Variability of Comprehensive Isokinetic Strength Assessment (PT)

April 7, 2026 updated by: Azza Mohammed, Cairo University

Role of Anthropometric Normalization in Inter-Individual Variability of Comprehensive Isokinetic Strength Assessment in Healthy Women: A Methodological Study

Accurate normalization of peak torque (PT) is critical for comparing muscle strength across individuals of varying body composition. While body weight (BW) is commonly used, body mass index (BMI) may provide a more stable representation of inter-individual variability. The study aims to compare the effects of BW and BMI normalization on inter-individual variability of trunk, hip, and knee muscle strength in healthy female participants.

Study Overview

Detailed Description

Accurate normalization of peak torque (PT) is critical for comparing muscle strength across individuals of varying body composition. While body weight (BW) is commonly used, body mass index (BMI) may provide a more stable representation of inter-individual variability. The study aims to compare the effects of BW and BMI normalization on inter-individual variability of trunk, hip, and knee muscle strength in healthy female participants.

Thirty healthy adult females will undergo isokinetic testing of trunk flexors/extensors, hip flexors/extensors/abductors/adductors, and knee flexors/extensors. PT values will be normalized to BW and BMI. Coefficient of variation (CV%) will be calculated for each method to evaluate relative variability.

Study Type

Observational

Enrollment (Estimated)

112

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Study Locations

      • Giza, Egypt, 12511
        • Faculty of physical therapy, Cairo University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

Yes

Sampling Method

Non-Probability Sample

Study Population

A total of 112 healthy sedentary females volunteered to participate in the study. Their demographic characteristics including age, weight, height and BMI are illustrated in Table 1. Ethical approval was obtained from the Research Ethics Committee of the Faculty of Physical Therapy, Cairo University. Prior to enrollment, all participants provided written informed consent after receiving a comprehensive explanation of the study objectives, procedures, and their rights as research subjects. All procedures were performed in accordance with the Helsinki Declaration. All participants provided informed written consent prior to participation, aligning with ethical standards for research with human subjects.

Description

Inclusion Criteria:

  • he absence of any current or prior musculoskeletal injury or pain affecting the trunk, pelvis, or lower extremities within the preceding six months.

    • absence of neurological, cardiovascular, or systemic conditions that could influence muscle strength or motor performance.
    • a normal BMI relative to their age and sex and were recreationally active without engaging in any structured strength training program targeting the trunk or hip muscles during the three months preceding the study.
    • all participants were able to comprehend the study procedures and provide written informed consent.

Exclusion Criteria:

  • any history of musculoskeletal injury, surgery, or chronic pain involving the spine, pelvis, hip, knee, or ankle. Individuals with diagnosed neurological disorders, balance impairments, or vestibular conditions were also ineligible.
  • cardiovascular, respiratory, or systemic diseases that could affect physical performance or muscle strength were excluded
  • a prior history of lower limb or trunk fractures. Individuals engaged in competitive sports or structured resistance training programs targeting the trunk and lower limb muscles within the preceding three months were not included.
  • musculoskeletal deformities, leg length discrepancies, or any other condition that could interfere with the testing procedures

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
trunk muscle peak torque
Time Frame: two weeks
Isokinetic trunk muscle strength testing
two weeks
hip muscle peak torque
Time Frame: two weeks
Isokinetic hip muscle strength testing
two weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Investigators

  • Principal Investigator: Azza M, professor, Cairo University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

March 30, 2026

Primary Completion (Estimated)

April 28, 2026

Study Completion (Estimated)

April 30, 2026

Study Registration Dates

First Submitted

March 27, 2026

First Submitted That Met QC Criteria

March 27, 2026

First Posted (Actual)

April 2, 2026

Study Record Updates

Last Update Posted (Actual)

April 9, 2026

Last Update Submitted That Met QC Criteria

April 7, 2026

Last Verified

April 1, 2026

More Information

Terms related to this study

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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