- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07521813
Psychiatric Disorders in Dermatiological Diseases
Evaluation of Body Dysmorphic Disorder in Children With Dermatological Diseases
The aim of this study:
- Evaluate the presence of body dysmorphic disorder in children with dermatological diseases compared to healthy controls.
- Assess the effect of these skin diseases on the quality of life in those children.
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
Skin diseases are the fourth leading cause of non-fatal disease in humans. Worldwide, between 30% and 70% of individuals are affected. Most dermatological conditions have an impact on patients' social, physical, and emotional well-being, as well as their friends, partners, and families.
The psychological impact of skin diseases is an issue of increasing concern worldwide but little research or exploration in this area has been undertaken.Pediatric psychodermatology is an emerging field that is uniquely tailored to the developmental, emotional, and psychosocial needs of children with psychocutaneous conditions.
Body dysmorphic disorder (BDD) is a psychiatric condition defined as a preoccupation with a perceived defect or flaw in one's physical appearance when, in fact, they appear normal. BDD falls under the spectrum of obsessive-compulsive and related disorders.
Often under recognized, BDD is a prevalent disorder characterized by an all-consuming focus on perceived physical imperfections, leading to distressing repetitive actions and, at times, suicidal behavior and ideation. Individuals with BDD often seek unnecessary surgical interventions.
The affected patients visit dermatology and plastic surgery clinics to repair their perceived defects. Understanding BDD's features and diagnostic criteria across all healthcare specialties helps increase awareness and recognition of the condition.
Body dysmorphic disorder is commonly first encountered by nonpsychiatric physicians. It is estimated to range from 0.7% to 2.4% in general clinics met diagnostic criteria for BDD, increasing to 9% to 12% in general dermatology clinics, 8% to 37% in cosmetic dermatology clinics, 2.9% to 53.6% in cosmetic surgery clinics and 14.1% among patients with chronic skin disease. These findings highlight the strong link between skin disorders and BDD, supporting the importance of studying this link specially in children and adolescents.
Most research on BDD focuses on adolescents and adults, however childhood- BDD remain underestimated because appearance concerns may be misinterpreted as normal developmental features. Children with early symptoms may hide their worries or struggle to express them, contributing to diagnostic delay.
Chronic pediatric dermatological diseases including atopic dermatitis, psoriasis, vitiligo, alopecia areata, and acne vulgaris are associated with a significant psychological burden. Commonly reported psychiatric manifestations include anxiety, depression, low self-esteem, social withdrawal, and impaired quality of life. More severe comorbidities such as ADHD, obsessive-compulsive disorder, bipolar disorder, psychotic disorders, substance use, eating disorders, and suicidal ideation have also been described.
Screening for BDD by dermatologists is of paramount importance. Dermatologists should ask patients with minimal or non-existing defects about how much time each day they spend in thinking about their defects and how much such concerns cause distress or interfere with functioning. Patients who are concerned and preoccupied with perceived defects, spending at least one hour thinking about them and their concerns lead to functioning impairment or clinically significant distress should be considered for BDD diagnosis.
Given the emerging evidence linking skin diseases with body image disturbances in young populations , It is essential to investigate the prevalence, associated factors, and psychosocial impact of BDD among children with skin disorders. This supports the development of early screening programs and collaborative models between dermatology and child mental health services.Early recognition and intervention may significantly improve both psychological well-being and dermatological treatment outcomes in affected children.
Study Type
Enrollment (Estimated)
Contacts and Locations
Study Contact
- Name: Aya Abdelhaseb Abdellatif, Resident doctor
- Phone Number: 00201142639444
- Email: aya.abdelhasseb@med.sohag.edu.eg
Study Contact Backup
- Name: Zeinab Abuelbaha Gouda, Lecturer
- Phone Number: 00201025863400
- Email: Zeinabgouda3415@med.sohag.edu.eg
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
Accepts Healthy Volunteers
Sampling Method
Study Population
Description
Inclusion Criteria:
- The study will include 250 children of both sexes aged from six up to less than 18 years presenting with various chronic skin diseases, diagnosed clinically, by dermoscopy and by biopsy if needed, and age and sex matched healthy controls.
- Ability of the child and caregiver to understand and respond to the questionnaires.
Exclusion Criteria:
- Children with diagnosed psychiatric disorders other than BDD (e.g., severe depression, autism spectrum disorder).
- Children with chronic systemic illness affecting body image or any other debilitating acute , chronic illness or surgical problems e.g.: short stature, hypothyroidism, osteochondral defects and obesity.
Study Plan
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Evaluation of Body Dysmorphic Disorder in Children with Dermatological Diseases
Time Frame: From Apri 2026 to April 2027
|
Evaluate the presence of body dysmorphic disorder in children with dermatological diseases compared to healthy controls. The study will include 250 children of both sexes aged from six to less than 18 years presented with various chronic skin diseases, diagnosed clinically , by dermoscopy and by biopsy if needed, and 250 age and sex matched healthy controls . Assessment of the severity of the dermatological diseases according to available valid severity scores will be done . Body Dysmorphic Disorder Questionnaire Dermatology Version will be done to identify symptoms of body dysmorphic disorder with valid standardized arabic version . The body dysmorphic disorder questionnaire is a brief, validated questionnaire used to identify patients having symptoms of BDD. It uses close-ended questions and identifies if participants' concerns regarding appearance are a source of preoccupation and identifies the grade of distress or interference with social and occupational functioning . |
From Apri 2026 to April 2027
|
|
Assess the effect of skin diseases on the quality of life of children
Time Frame: From April 2026 to April 2027
|
Assess the effect of skin diseases on the quality of life in children by using Children's Dermatology Life Quality Index questionnaire (CDLQI) that used to evaluate the psychosocial impact of skin disease with valid standardized Arabic version . The study will include 250 children of both sexes aged from six up to less than 18 years presenting with various chronic skin diseases, diagnosed clinically, by dermoscopy and by biopsy if needed, and 250 age and sex matched healthy controls then Children's Dermatology Life Quality Index questionnaire (CDLQI) will be assessed with a valid standardized Arabic version . The Children's Dermatology Life Quality Index (CDLQI) is a validated questionnaire to assess the impact of skin diseases on the quality of life of children. It evaluates the effect of dermatological conditions on physical symptoms, emotional well-being, daily activities, social interactions, school performance, and treatment. |
From April 2026 to April 2027
|
Collaborators and Investigators
Sponsor
Investigators
- Study Director: Soha Hishmat Aboeldahab, Professor, Sohag University
Publications and helpful links
General Publications
- Arumugham SS, Narayanaswamy JC, Balachander S, Sharma E, Jaisoorya TS, Reddy SC, Siddiqui AM, Desouza A, Shah PS, Reddy YJ. Clinical practice guidelines for obsessive-compulsive disorder: 2025 update. Indian J Psychiatry. 2026 Jan;68(1):44-67. doi: 10.4103/indianjpsychiatry_1259_25. Epub 2026 Jan 27.
- Ruck C, Mataix-Cols D, Feusner JD, Shavitt RG, Veale D, Krebs G, Fernandez de la Cruz L. Body dysmorphic disorder. Nat Rev Dis Primers. 2024 Dec 5;10(1):92. doi: 10.1038/s41572-024-00577-z.
- Sa B, Khalil N, Edwards E, Smith A, Franca K. Pediatric Psychodermatology: Advancing Therapy through Integrated Care. Dermatol Ther (Heidelb). 2026 Mar;16(3):1455-1472. doi: 10.1007/s13555-026-01673-6. Epub 2026 Feb 16.
- Salari N, Heidarian P, Hosseinian-Far A, Babajani F, Mohammadi M. Global Prevalence of Anxiety, Depression, and Stress Among Patients with Skin Diseases: A Systematic Review and Meta-analysis. J Prev (2022). 2024 Aug;45(4):611-649. doi: 10.1007/s10935-024-00784-0. Epub 2024 Jun 1.
Study record dates
Study Major Dates
Study Start (Estimated)
Primary Completion (Estimated)
Study Completion (Estimated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- Soh-Med-26-3-14MS
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Body Dysmorhpic Disorder
-
Karolinska InstitutetCompletedBody Dysmorhpic DisorderSweden
-
Stanford UniversityRecruitingObsessive-Compulsive Disorder | Body Dysmorphic Disorders | Illness Anxiety DisorderUnited States
-
Academisch Medisch Centrum - Universiteit van Amsterdam...RecruitingObsessive-Compulsive Disorder | Anxiety Disorders | Body Dysmorphic DisordersNetherlands
-
University of AarhusGE HealthcareCompletedSodium Disorder | Image, BodyDenmark
-
Massachusetts General HospitalCompletedBody Dysmorphic Disorder | Obsessive-compulsive DisorderUnited States
-
Stanford UniversityAvy L. & Roberta L. Miller FoundationRecruitingObsessive-Compulsive Disorder | Body Dysmorphic Disorders | Illness Anxiety Disorder | Somatic Symptom DisorderUnited States
-
University of WashingtonNational Institute of Mental Health (NIMH)RecruitingSocial Anxiety Disorder | Body Dysmorphic DisorderUnited States
-
Massachusetts General HospitalNational Institute of Mental Health (NIMH)CompletedAnxiety Disorders | Somatoform Disorders | Body Dysmorphic Disorder | Obsessive-Compulsive Spectrum DisorderUnited States
-
Lawson Health Research InstituteCompletedMajor Depressive DisorderCanada
-
Massachusetts General HospitalNational Institute of Mental Health (NIMH); Rhode Island HospitalCompletedAnxiety Disorders | Somatoform DisordersUnited States
Clinical Trials on Questionnaire and Physical Exam
-
University Hospital, MontpellierNot yet recruiting
-
University Hospital, GrenobleRecruiting
-
Medical University of SilesiaSt. Boniface Hospital; Klinika Ginekologii i Ginekologii Onkologicznej CMKP; I...Not yet recruitingEndometrial Hyperplasia | Abnormal Uterine Bleeding Unrelated to Menstrual Cycle | Pelvic Organ Prolapse (POP) | Uterine Fibroids (UF)Poland
-
Fondazione Policlinico Universitario Agostino Gemelli...Not yet recruitingPrognathism | Psychiatric Disorders | Orthognathic Surgical ProceduresItaly
-
Bahria UniversityNot yet recruitingCardiac Patients
-
Wei XIA, PhDNot yet recruitingAddiction | Drug MisuseChina
-
Bursa City HospitalCompleted
-
Marmara UniversityCompleted
-
IRCCS San RaffaeleRecruitingSleep | Temporomandibular Disorders (TMD)Italy
-
Poitiers University HospitalNot yet recruitingCognitive Impairment | Alzheimer Disease | Deafness | Memory | Neuropsychological Tests | Sign Language