Functional and Respiratory Predictors of Early Postoperative Outcomes

April 9, 2026 updated by: Müşerref Ebru YALÇIN

The Effect of Functional Status and Respiratory Parameters on Early Postoperative Clinical Outcomes in Patients With Colorectal Cancer

Functional status is a fundamental indicator reflecting a patient's ability to perform activities of daily living and is closely associated with early postoperative outcomes. Patients with low functional capacity are known to have an increased risk of postoperative complications, prolonged length of hospital stay, and higher mortality rates. Similarly, respiratory function plays a decisive role in the development of postoperative complications and influences early surgical outcomes. In the preoperative period, inadequate respiratory capacity and poor functional performance increase the risk of postoperative pulmonary complications and delayed recovery. Therefore, functional and respiratory assessments are regarded as integral components of the preoperative preparation process.

Early outcomes in patients undergoing colorectal cancer surgery are of critical importance in reducing mortality and morbidity. In this surgical population, advanced age, comorbidities, and diminished physical capacity may further increase the risk of postoperative complications. Accordingly, the evaluation of preoperative functional status and physiological reserve has gained increasing importance for risk stratification and perioperative management. However, studies examining the impact of functional status and respiratory parameters on early surgical outcomes in patients with colorectal cancer remain limited. Consequently, the available evidence is insufficient to establish a standardized assessment approach in clinical practice.

Moreover, objective evaluation of patients' functional and respiratory capacities in the preoperative period is essential for predicting surgical risk and planning individualized perioperative care. Determining the relationships between these parameters and early clinical outcomes may facilitate the identification of high-risk patients and contribute to the development of targeted strategies aimed at preventing postoperative complications. Findings obtained in this context are expected to provide a scientific basis for clinical decision-making and multidisciplinary patient management in individuals undergoing colorectal cancer surgery, thereby guiding clinical practice.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Estimated)

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Name: Müşerref Ebru YALÇIN
Phone Number: +90 555 713 6666
Email: M.ebrusen@gmail.com

Study Locations

Turkey (Türkiye)
- - Malatya, Turkey (Türkiye)
    - Recruiting
    - İnönü University Turgut Özal Medical Center General Surgery Polyclinic
    - Contact:
      
      Egemen Çiçek

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

Adult
Older Adult

Accepts Healthy Volunteers

Sampling Method

Non-Probability Sample

Study Population

Individuals aged between 18 and 80 years who have undergone colorectal cancer surgery and who voluntarily agree to participate in the study will be included.

Description

Inclusion Criteria

Being between 18 and 80 years of age

Voluntary agreement to participate in the study

Exclusion Criteria

Withdrawal from the study at the participant's own request

Elimination Criteria

Presence of a musculoskeletal condition that may prevent completion of the planned assessments

Presence of a mental impairment

History of psychiatric disorder

History of previous major surgery

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Short Physical Performance Battery (SPPB) Time Frame: 1 year	Short Physical Performance Battery (SPPB): This scale is used to assess lower extremity physical performance. The total score ranges from 0 to 12, with higher scores indicating better physical performance.	1 year

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Müşerref Ebru YALÇIN

Collaborators

Inonu University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

March 1, 2026

Primary Completion (Estimated)

August 25, 2026

Study Completion (Estimated)

February 25, 2027

Study Registration Dates

First Submitted

March 4, 2026

First Submitted That Met QC Criteria

April 9, 2026

First Posted (Actual)

April 14, 2026

Study Record Updates

Last Update Posted (Actual)