Ibutilide Administration During Pulmonary Vein Ablation (IBAD-AFIB)

Inclusion Criteria:

• patients to be scheduled for atrial fibrillation radio frequency ablation
• paroxysmal, permanent symptomatic atrial fibrillation refractory to conventional treatment
• symptomatic atrial fibrillation that do not want or desire to take medication or undergo cardioversion
• patients on antiarrhythmics that can be discontinued 5 half lifes prior to the procedure except for Amiodarone

Exclusion Criteria:

• patients with recent major hemorrhage (within 6 months)
• patients with a coagulopathy
• patients who are pregnant or breast feeding
• patients with acute congestive heart failure
• patients with hypokalemia or hyperkalemia
• patients with a prolonged QTc > 440mms
• patients with polymorphic ventricular tachycardia secondary to antiarrhythmic class III and class I
• patients with left ventricular dysfunction < 40%
• patients with a history of recent MI (< 1 month)
• patients with a history of an angioplasty of < 1 month
• patients with a history of coronary artery bypass grafting surgery of < 3 months.
• patients with a history of chronic renal failure or a creatinine clearance of < 30ml/m
• patients with a history of stroke of < 6 months