Erythrocyte and Adipocyte G6PD Activity Levels in Obesity

Erythrocyte and Adipocyte G6PD Activity Levels Correlate With Differing Degrees of Dyslipidemia, Insulin Resistance and Obesity

Patrocinadores

Patrocinador principal: University of South Alabama

Fuente University of South Alabama
Resumen breve

This study compares the improvement of weight, fasting lipid profile (triglycerides, cholesterol, HDL, and LDL) and diabetes after gastric bypass surgery with an improvement in levels of an enzyme called glucose-6-phosphate dehydrogenase (G6PD).

Descripción detallada

Same as brief summary

Estado general Completed
Fecha de inicio December 2009
Fecha de Terminación March 2013
Fecha de finalización primaria March 2013
Tipo de estudio Observational
Resultado primario
Medida Periodo de tiempo
Measure erythrocyte G6PD levels in diabetic vs. non-diabetic morbidly obese patients undergoing laparoscopic Gastric Bypass. time of surgery up to 24 months post gastric bypass
Resultado secundario
Medida Periodo de tiempo
Measure adipocyte G6PD levels in diabetic vs. non-diabetic morbidly obese patients undergoing laparoscopic gastric bypass. time of surgery up to 12 weeks post gastric bypass
Measure omentum G6PD levels in diabetic vs. non-diabetic morbidly obese patients undergoing laparoscopic gastric bypass. time of surgery up to 12 weeks post gastric bypass
Measure hepatocyte G6PD levels in diabetic vs. non-diabetic morbidly obese patients undergoing laparoscopic gastric bypass. time of surgery up to 12 weeks post gastric bypass
Inscripción 16
Condición
Elegibilidad

Método de muestreo: Probability Sample

Criterios:

Inclusion Criteria:

- Age > 19 years of age and <70 years of age

- HGA1c<6.0%

- fasting blood sugar less than 100mg/dL

Exclusion Criteria:

- Taking antidiabetic medications for other indications

Género: All

Edad mínima: 19 Years

Edad máxima: 70 Years

Voluntarios Saludables: No

Oficial general
Apellido Papel Afiliación
William O Richards, MD Principal Investigator University of South Alabama, Department of Surgery
Ubicación
Instalaciones:
Mobile Infirmary Medical Center | Mobile, Alabama, 36607, United States
University of South Alabama | Mobile, Alabama, 36617, United States
Ubicacion Paises

United States

Fecha de verificación

January 2013

Fiesta responsable

Tipo: Principal Investigator

Afiliación del investigador: University of South Alabama

Nombre completo del investigador: William Richards

Título del investigador: principal investigator

Tiene acceso ampliado No
Condición Examinar
Información de diseño del estudio

Modelo de observación: Cohort

Perspectiva de tiempo: Prospective

Fuente: ClinicalTrials.gov