Procalcitonin Role in Influenza Patients With Regard to Morbidity, Mortality and Antibiotic Use

Procalcitonin Role in Influenza Patients With Regard to Morbidity, Mortality and Antibiotic Use

Patrocinadores

Patrocinador principal: Ostfold Hospital Trust

Fuente Ostfold Hospital Trust
Resumen breve

The investigators intend to observe the inflammatory marker procalcitonin (PCT) in comparison with patient variables on morbidity, mortality and antibiotic treatment.

The overall aim is to observe if a low PCT value can have potential in reducing unessesary antibiotic use in seasonal influenza patients.

Descripción detallada

This is an observational study of the clinical utility of early PCT measurements in seasonal influenza, with particular attention to PCT's predictive value for prognosis and bacterial respiratory superinfection. The aim is to evaluate PCT as a supplementary aid in the standard clinical evaluation of influenza patients. Patients may be included if a positive influenza test is reported within 48 hours after an initial clinical suspicion of influenza, and the hospital stay is lasting more than one day. The investigators have included 74 patients from the second half of the 2018-19 influenza season and will continue to include patients from the complete 2019-20 season.

Primary endpoints: Mortality (in-hospital and within 30 days post-discharge), bacterial respiratory tract superinfection.

Secondary endpoints: Intensive care unit stay, the proportion of patients on antibiotic use and total antibiotic use in doses and LOT ("length-of-treatment").

Estado general Not yet recruiting
Fecha de inicio November 15, 2019
Fecha de Terminación August 1, 2020
Fecha de finalización primaria April 15, 2020
Tipo de estudio Observational
Resultado primario
Medida Periodo de tiempo
mortality 30 days
Resultado secundario
Medida Periodo de tiempo
antibiotic use up to one year
Inscripción 250
Condición
Intervención

Tipo de intervención: Behavioral

Nombre de intervención: antibiotic stewardship efforts

Descripción: The local antibiotic team plan to implement procalcitonin use among the hospital physicians. the interventions are not ready yet.

Elegibilidad

Método de muestreo: Non-Probability Sample

Criterios:

Inclusion Criteria:

- patient admitted to the hospital with positive influenza test

Exclusion Criteria:

- none

Género: All

Edad mínima: 18 Years

Edad máxima: N/A

Voluntarios Saludables: No

Contacto general

Apellido: Ingrid Christensen, MD

Teléfono: 004790733113

Email: [email protected]

Ubicación
Instalaciones: Ostfold Hospital Trust
Ubicacion Paises

Norway

Fecha de verificación

November 2019

Fiesta responsable

Tipo: Sponsor

Palabras clave
Tiene acceso ampliado No
Condición Examinar
Datos del paciente No
Información de diseño del estudio

Modelo de observación: Case-Only

Perspectiva de tiempo: Prospective

Fuente: ClinicalTrials.gov