Feasibility of Online MR-guided Radiotherapy on a 1.5T MR-Linac

Feasibility of Imaging and Radiotherapy on a Novel 1.5 T Hybrid Magnetic Resonance Imaging - Linear Accelerator System (MR-Linac)

Patrocinadores

Patrocinador principal: University Hospital Tuebingen

Fuente University Hospital Tuebingen
Resumen breve

This study investigates the feasibility of imaging and treatment on a novel 1.5 T MR-Linac radiotherapy hybrid device.

Descripción detallada

Novel hybrid devices combine magnetic resonance imaging (MRI) and a linear accelerator in a single device. The superior soft tissue contrast compared with cone-beam computed tomography based treatment and the possibility for daily plan adaptation promise a higher precision of treatment, better target volume coverage and normal tissue sparing. In a first step the present study will test the feasibility of imaging and treatment on the 1.5 T MR-Linac.

Estado general Recruiting
Fecha de inicio May 9, 2018
Fecha de Terminación May 9, 2027
Fecha de finalización primaria May 9, 2022
Fase N/A
Tipo de estudio Interventional
Resultado primario
Medida Periodo de tiempo
Feasibility of online MR guided Radiotherapy During every single patients treatment (i.e. between one to seven weeks after the first application of radiotherapy)
Resultado secundario
Medida Periodo de tiempo
Time analysis During every single patients treatment (i.e. between one to seven weeks after the first application of radiotherapy)
Inscripción 472
Condición
Intervención

Tipo de intervención: Radiation

Nombre de intervención: Radiotherapy on the MR-Linac

Descripción: Radiotherapy is performed on the 1.5 T MR Linac

Tipo de intervención: Diagnostic Test

Nombre de intervención: Imaging on the MR Linac

Descripción: Only imaging performed on the MR Linac

Etiqueta de grupo de brazo: Imaging only

Elegibilidad

Criterios:

Inclusion Criteria:

- existing indication for radiation therapy

- minimum age 18 years, no upper age limit

- capacity for consent

- Informed consent

Exclusion Criteria:

- contraindication for MRI (claustrophobia, metallic implants not applicable for MRI

- pregnancy

Género: All

Edad mínima: 18 Years

Edad máxima: N/A

Voluntarios Saludables: No

Ubicación
Instalaciones: Estado: Contacto: Copia de seguridad de contactos: University Hospital Tübingen, Department of Radiation Oncology Daniel Zips, MD, Prof +49 (0) 7071 29-85990 [email protected]
Ubicacion Paises

Germany

Fecha de verificación

November 2019

Fiesta responsable

Tipo: Principal Investigator

Afiliación del investigador: University Hospital Tuebingen

Nombre completo del investigador: Dr. Cihan Gani

Título del investigador: Lead of gastrointestinal radiation oncology

Palabras clave
Tiene acceso ampliado No
Número de brazos 9
Grupo de brazo

Etiqueta: Rectal and anal cancer

Tipo: Experimental

Descripción: In this arm patients with rectal and anal cancer are recruited.

Etiqueta: Prostate cancer

Tipo: Experimental

Descripción: In this arm patients with prostate cancer are recruited.

Etiqueta: Head and neck cancer

Tipo: Experimental

Descripción: In this arm patients with head and neck cancers are recruited.

Etiqueta: Esophageal cancer

Tipo: Experimental

Descripción: In this arm patients with esophageal cancer are recruited.

Etiqueta: Breast Cancer

Tipo: Experimental

Descripción: In this arm patients with breast cancer are recruited.

Etiqueta: Central nervous system tutors

Tipo: Experimental

Descripción: In this arm patients with tumors of the central nervous system are recruited.

Etiqueta: Palliative treatments

Tipo: Experimental

Descripción: In this arm patients with palliative treatments are recruited.

Etiqueta: Other

Tipo: Experimental

Descripción: In this arm patients with other tumors are recruited.

Etiqueta: Imaging only

Tipo: Experimental

Descripción: In this arm patients receive only imaging on the MR-Linac

Información de diseño del estudio

Asignación: Non-Randomized

Modelo de intervención: Single Group Assignment

Propósito primario: Treatment

Enmascaramiento: None (Open Label)

Fuente: ClinicalTrials.gov