- ICH GCP
- 미국 임상 시험 레지스트리
- 임상시험 NCT02799277
도덕적 판단의 다항 프로세스 모델 (PSY)
The main goal of this project to investigate the psychological processes underlying moral judgments in social dilemmas. We will examine neuroendocrine determinants of moral judgment by investigating the effects of exogenous testosterone
연구 개요
상세 설명
- Medical Screening Interview: Participants will be asked to answer several questions to identify potential medical and non-medical conditions that would preclude the self-administration of testosterone.
- First Saliva Sample: Participants will be asked provide a saliva sample after they completed the medical screening interview.
- Testosterone Self-Administration: Immediately following the first saliva collection, participants will self-administer spray puffs of either testosterone or placebo.
- Relaxation: Participants will be given the opportunity to relax for 30 minutes.
- Moral Dilemmas Judgments: Participants will be asked to read a set of 24 moral dilemmas that describe situations in which an actor has to make a decision on whether or not to engage in a particular action (e.g., sacrifice the well-being of one person to protect the well-being of several others). Participants will be asked to indicate whether they consider the described action acceptable or unacceptable.
- Demographics: Participants will be asked to indicate their gender, age, and ethnicity.
- Ear Temperature, heart rate, and blood pressure will be measured before drug administration, and again 20 minutes after drug administration. If temperature changes more than 2 degrees, heart rate changes more than 20bmp, or if blood pressure changes more than 20%, the experiment will be terminated and subjects will be escorted across the street to the University Emergency Room.
연구 유형
등록 (실제)
단계
- 4단계
연락처 및 위치
연구 장소
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Texas
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Austin, Texas, 미국, 78712
- University of Texas at Austin Department of Psychology
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참여기준
자격 기준
공부할 수 있는 나이
건강한 자원 봉사자를 받아들입니다
연구 대상 성별
설명
Inclusion Criteria:
- must be currently enrolled at The University of Texas at Austin
Exclusion Criteria:
- not comfortable with the self-administration of testosterone for the purpose of our study less than 18 years old BMI less than 18 or above 27 suffer from any of the physical health conditions listed on the pre-screen questionnaire (I will not ask about mental health because our study is not about mental health) take any of the medications listed on the pre-screen questionnaire currently pregnant (females) irregular cycle in the past 6 months (females) smoke more than 5 cigarettes/day use cocaine more than once/month (**or should I exclude all those who use any drugs recreationally more than once/month?**) drink more than 10 alcoholic beverages/week
공부 계획
연구는 어떻게 설계됩니까?
디자인 세부사항
- 주 목적: 기초 과학
- 할당: 무작위
- 중재 모델: 병렬 할당
- 마스킹: 삼루타
무기와 개입
참가자 그룹 / 팔 |
개입 / 치료 |
|---|---|
|
실험적: Testosterone
14mg testosterone will be administered intranasally in a 1milliliter aqueous solution |
Effect of testosterone on moral decision making |
|
위약 비교기: Placebo
1ml blank (containing no drug) aqueous solution will be administered intranasally |
Effect of testosterone on moral decision making |
연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
|
Probability of Making a Moral Judgment That Aligns With Moral Norms
기간: 90 minutes
|
Participants were asked to read and respond to a validated set of 24 moral dilemmas. The dilemma set included 4 parallel versions of 6 basic scenarios that varied in terms of whether (a) the dilemma involved a proscriptive norm that prohibits action or a prescriptive norm that prescribes action and (b) the benefits of the described action for overall well-being are either greater or smaller than its costs for overall well-being. Participants were asked to indicate for each dilemma whether or not they would perform the described action, using forced-choice options labeled yes and no. |
90 minutes
|
|
Probability of Making a Moral Judgment That Maximizes Welfare
기간: 90 minutes
|
Participants were asked to read and respond to a validated set of 24 moral dilemmas. The dilemma set included 4 parallel versions of 6 basic scenarios that varied in terms of whether (a) the dilemma involved a proscriptive norm that prohibits action or a prescriptive norm that prescribes action and (b) the benefits of the described action for overall well-being are either greater or smaller than its costs for overall well-being. Participants were asked to indicate for each dilemma whether or not they would perform the described action, using forced-choice options labeled yes and no. |
90 minutes
|
|
Probability of Making a Moral Judgment That Involves Inaction Versus Action
기간: 90 minutes
|
Participants were asked to read and respond to a validated set of 24 moral dilemmas. The dilemma set included 4 parallel versions of 6 basic scenarios that varied in terms of whether (a) the dilemma involved a proscriptive norm that prohibits action or a prescriptive norm that prescribes action and (b) the benefits of the described action for overall well-being are either greater or smaller than its costs for overall well-being. Participants were asked to indicate for each dilemma whether or not they would perform the described action, using forced-choice options labeled yes and no. |
90 minutes
|
공동 작업자 및 조사자
스폰서
수사관
- 수석 연구원: Robert A Josephs, PhD, Professor
연구 기록 날짜
연구 주요 날짜
연구 시작 (실제)
기본 완료 (실제)
연구 완료 (실제)
연구 등록 날짜
최초 제출
QC 기준을 충족하는 최초 제출
처음 게시됨 (추정된)
연구 기록 업데이트
마지막 업데이트 게시됨 (실제)
QC 기준을 충족하는 마지막 업데이트 제출
마지막으로 확인됨
추가 정보
이 연구와 관련된 용어
추가 관련 MeSH 약관
기타 연구 ID 번호
- 2014-12-0010
개별 참가자 데이터(IPD) 계획
개별 참가자 데이터(IPD)를 공유할 계획입니까?
약물 및 장치 정보, 연구 문서
미국 FDA 규제 의약품 연구
미국 FDA 규제 기기 제품 연구
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