- ICH GCP
- Реестр клинических исследований США
- Клиническое испытание NCT02799277
Полиномиальная модель процесса морального суждения (PSY)
The main goal of this project to investigate the psychological processes underlying moral judgments in social dilemmas. We will examine neuroendocrine determinants of moral judgment by investigating the effects of exogenous testosterone
Обзор исследования
Статус
Условия
Вмешательство/лечение
Подробное описание
- Medical Screening Interview: Participants will be asked to answer several questions to identify potential medical and non-medical conditions that would preclude the self-administration of testosterone.
- First Saliva Sample: Participants will be asked provide a saliva sample after they completed the medical screening interview.
- Testosterone Self-Administration: Immediately following the first saliva collection, participants will self-administer spray puffs of either testosterone or placebo.
- Relaxation: Participants will be given the opportunity to relax for 30 minutes.
- Moral Dilemmas Judgments: Participants will be asked to read a set of 24 moral dilemmas that describe situations in which an actor has to make a decision on whether or not to engage in a particular action (e.g., sacrifice the well-being of one person to protect the well-being of several others). Participants will be asked to indicate whether they consider the described action acceptable or unacceptable.
- Demographics: Participants will be asked to indicate their gender, age, and ethnicity.
- Ear Temperature, heart rate, and blood pressure will be measured before drug administration, and again 20 minutes after drug administration. If temperature changes more than 2 degrees, heart rate changes more than 20bmp, or if blood pressure changes more than 20%, the experiment will be terminated and subjects will be escorted across the street to the University Emergency Room.
Тип исследования
Регистрация (Действительный)
Фаза
- Фаза 4
Контакты и местонахождение
Места учебы
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Texas
-
Austin, Texas, Соединенные Штаты, 78712
- University of Texas at Austin Department of Psychology
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Критерии участия
Критерии приемлемости
Возраст, подходящий для обучения
Принимает здоровых добровольцев
Полы, имеющие право на обучение
Описание
Inclusion Criteria:
- must be currently enrolled at The University of Texas at Austin
Exclusion Criteria:
- not comfortable with the self-administration of testosterone for the purpose of our study less than 18 years old BMI less than 18 or above 27 suffer from any of the physical health conditions listed on the pre-screen questionnaire (I will not ask about mental health because our study is not about mental health) take any of the medications listed on the pre-screen questionnaire currently pregnant (females) irregular cycle in the past 6 months (females) smoke more than 5 cigarettes/day use cocaine more than once/month (**or should I exclude all those who use any drugs recreationally more than once/month?**) drink more than 10 alcoholic beverages/week
Учебный план
Как устроено исследование?
Детали дизайна
- Основная цель: Фундаментальная наука
- Распределение: Рандомизированный
- Интервенционная модель: Параллельное назначение
- Маскировка: Тройной
Оружие и интервенции
Группа участников / Армия |
Вмешательство/лечение |
|---|---|
|
Экспериментальный: Testosterone
14mg testosterone will be administered intranasally in a 1milliliter aqueous solution |
Effect of testosterone on moral decision making |
|
Плацебо Компаратор: Placebo
1ml blank (containing no drug) aqueous solution will be administered intranasally |
Effect of testosterone on moral decision making |
Что измеряет исследование?
Первичные показатели результатов
Мера результата |
Мера Описание |
Временное ограничение |
|---|---|---|
|
Probability of Making a Moral Judgment That Aligns With Moral Norms
Временное ограничение: 90 minutes
|
Participants were asked to read and respond to a validated set of 24 moral dilemmas. The dilemma set included 4 parallel versions of 6 basic scenarios that varied in terms of whether (a) the dilemma involved a proscriptive norm that prohibits action or a prescriptive norm that prescribes action and (b) the benefits of the described action for overall well-being are either greater or smaller than its costs for overall well-being. Participants were asked to indicate for each dilemma whether or not they would perform the described action, using forced-choice options labeled yes and no. |
90 minutes
|
|
Probability of Making a Moral Judgment That Maximizes Welfare
Временное ограничение: 90 minutes
|
Participants were asked to read and respond to a validated set of 24 moral dilemmas. The dilemma set included 4 parallel versions of 6 basic scenarios that varied in terms of whether (a) the dilemma involved a proscriptive norm that prohibits action or a prescriptive norm that prescribes action and (b) the benefits of the described action for overall well-being are either greater or smaller than its costs for overall well-being. Participants were asked to indicate for each dilemma whether or not they would perform the described action, using forced-choice options labeled yes and no. |
90 minutes
|
|
Probability of Making a Moral Judgment That Involves Inaction Versus Action
Временное ограничение: 90 minutes
|
Participants were asked to read and respond to a validated set of 24 moral dilemmas. The dilemma set included 4 parallel versions of 6 basic scenarios that varied in terms of whether (a) the dilemma involved a proscriptive norm that prohibits action or a prescriptive norm that prescribes action and (b) the benefits of the described action for overall well-being are either greater or smaller than its costs for overall well-being. Participants were asked to indicate for each dilemma whether or not they would perform the described action, using forced-choice options labeled yes and no. |
90 minutes
|
Соавторы и исследователи
Спонсор
Следователи
- Главный следователь: Robert A Josephs, PhD, Professor
Даты записи исследования
Изучение основных дат
Начало исследования (Действительный)
Первичное завершение (Действительный)
Завершение исследования (Действительный)
Даты регистрации исследования
Первый отправленный
Впервые представлено, что соответствует критериям контроля качества
Первый опубликованный (Оцененный)
Обновления учебных записей
Последнее опубликованное обновление (Действительный)
Последнее отправленное обновление, отвечающее критериям контроля качества
Последняя проверка
Дополнительная информация
Термины, связанные с этим исследованием
Дополнительные соответствующие термины MeSH
Другие идентификационные номера исследования
- 2014-12-0010
Планирование данных отдельных участников (IPD)
Планируете делиться данными об отдельных участниках (IPD)?
Информация о лекарствах и устройствах, исследовательские документы
Изучает лекарственный продукт, регулируемый FDA США.
Изучает продукт устройства, регулируемый Управлением по санитарному надзору за качеством пищевых продуктов и медикаментов США.
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