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The Patellofemoral Pain Functional Performance Study (PFP-FP)
The Patellofemoral Pain Functional Performance and Arthrogenic Muscle Inhibition Study
Studie Overzicht
Toestand
Conditie
Interventie / Behandeling
Gedetailleerde beschrijving
Patellofemoral pain (PFP) is one of the most frequently diagnosed conditions in patients with knee complaints.
Studies investigating the therapeutic effect on PFP revealed that the majority of patients with PFP were still suffering of knee pain after 5 to 8 years, despite initially received treatment and education, indicating that the current treatments fail to prevent the chronicity of symptoms. Considering that current treatment-strategies of patients with PFP seem to be unable to avoid the development of chronic symptoms, the question arises if the underlying factors of PFP are understood sufficiently.
In contrary to the current broad body of literature on weakness, potentially underlying factors which might influence or even lead to PFP, such arthrogenic muscle inhibition (AMI) or the break phenomenon remain understudied.
Pain in PFP has been proven to be linked to quadriceps strength deficit, gluteal strength deficits, knee stability, irregularities in the quadriceps torque curve, and functional performance. Bazett et al. (2011) described that pain "is more than a symptom and might play a role in the etiology or progression of PFP". Furthermore, pain seems to play a crucial role in AMI. However, the correlation between pain and AMI in patients with PFP has not been investigated currently.
No assessment in isolation can provide a full picture of the problem. The combination of AMI, the break phenomenon with a biomechanical analysis might enable the determination of the impact of inhibition and strength on biomechanical changes. In addition, it might provide an answer to whether AMI or weakness cause biomechanical alterations, which would help to optimise treatment approaches in PFP.
The PowersTM strap strap was developed with the aim of assisting lower limb kinematics, decreasing knee varus through supporting femoral abduction and external rotation. This treatment may potentially also directly improve functional performance. As the functional performance in participants with PFP after the application of the PowersTM strap has not been investigated, this study aims to analyse if there is a direct link between the application of the PowersTM strap to functional performance and pain.
Studietype
Inschrijving (Werkelijk)
Fase
- Niet toepasbaar
Contacten en locaties
Studie Locaties
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Greater Manchester
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Salford, Greater Manchester, Verenigd Koninkrijk, M66PU
- University of Salford
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Deelname Criteria
Geschiktheidscriteria
Leeftijden die in aanmerking komen voor studie
Accepteert gezonde vrijwilligers
Geslachten die in aanmerking komen voor studie
Beschrijving
Inclusion Criteria for patients with PFP:
- Reproducible pain with at least two of these activities: ascending or descending stairs or ramps, squatting, kneeling, prolonged sitting, hopping/ jumping, isometric quadriceps contraction or running
- Clearly defined pain location in the peripatellar region
- Reports of pain greater than 1 month duration.
- They are able to perform squatting, running and MVC task- Participant response
- Age range: 18-45 years old
Inclusion criteria for healthy volunteers:
- Healthy and without any previous lower limb injuries
- The participant is able to perform squatting, running and MVC task
Exclusion Criteria:
- Previous history of knee surgery
- Previous history of (traumatic) patella dislocation or instability
- Previous history of ligamentous instabilities
- Previous history of traumatic, inflammatory or infectious pathology in the lower extremity
- Previous history of internal derangement or other causes
- Previous diagnosed degenerative conditions in the knee
- Exclusion if patients cannot perform running, step down, or MVC task.
- Exclusion criteria for the healthy control group are: clinical evidence of other knee injury or knee pain, and current significant injury affecting other lower extremity joints.
Studie plan
Hoe is de studie opgezet?
Ontwerpdetails
- Primair doel: Behandeling
- Toewijzing: NVT
- Interventioneel model: Opdracht voor een enkele groep
- Masker: Geen (open label)
Wapens en interventies
Deelnemersgroep / Arm |
Interventie / Behandeling |
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Ander: healthy control
Healthy control group will attend one visit and functional performance, muscle strength and flexibility, quadriceps AMI, patellar position and posture will be measured.
No intervention will be applied.
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The powers strap aims to decrease knee varus through supporting femoral abduction and external rotation.
Participants will wear the Powers strap while performing functional tasks (running, squatting, single leg step down).
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Wat meet het onderzoek?
Primaire uitkomstmaten
Uitkomstmaat |
Maatregel Beschrijving |
Tijdsspanne |
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Influence of Powers strap
Tijdsspanne: 1 day
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The influence of the Powers strap on functional performance will be investigated by analysing hip and knee kinematics and kinetics with and without the Powers strap in participants with PFP
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1 day
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Medewerkers en onderzoekers
Sponsor
Studie record data
Bestudeer belangrijke data
Studie start
Primaire voltooiing (Werkelijk)
Studie voltooiing (Werkelijk)
Studieregistratiedata
Eerst ingediend
Eerst ingediend dat voldeed aan de QC-criteria
Eerst geplaatst (Schatting)
Updates van studierecords
Laatste update geplaatst (Werkelijk)
Laatste update ingediend die voldeed aan QC-criteria
Laatst geverifieerd
Meer informatie
Termen gerelateerd aan deze studie
Aanvullende relevante MeSH-voorwaarden
Andere studie-ID-nummers
- HSCR15-143
Deze informatie is zonder wijzigingen rechtstreeks van de website clinicaltrials.gov gehaald. Als u verzoeken heeft om uw onderzoeksgegevens te wijzigen, te verwijderen of bij te werken, neem dan contact op met register@clinicaltrials.gov. Zodra er een wijziging wordt doorgevoerd op clinicaltrials.gov, wordt deze ook automatisch bijgewerkt op onze website .
Klinische onderzoeken op PowersTM strap
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Decathlon SEEFOR, FranceWervingEpicondylitis | Elleboog verstuikingFrankrijk
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Samsung Medical CenterVoltooidSchildklierkankerKorea, republiek van
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Columbia UniversityWellinks, Inc.WervingAdolescente idiopathische scolioseVerenigde Staten
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Memorial Sloan Kettering Cancer CenterWervingCushing-syndroom | Ziekte van Cushing | Ziekte van CushingVerenigde Staten