Clinical Study on the Effectiveness and Safety Evaluation of Directional Atherectomy Combined With Drug-coated Balloons (Remove)

Inclusion Criteria:

• Age over 18 years old
• Ruthford grade 2-5 patients
• For patients whose arteries in both lower extremities meet the enrollment criteria, both lower extremities can be included
• At least one outflow tract over 10 cm at the distal end of the knee is continuous with a healthy back of the foot or internal and external arteries of the plantar
• The guide wire clearly passed through the lesion and the follow-up treatment was performed. In the case of failed anterograde passage, reverse puncture to achieve the guide wire through the lesion can also be included in the group
• After the failure of the first intracavitary treatment, the blood vessel can be recanalized by the intracavitary treatment again, and it can still be included in the group
• Patients with aortic iliac artery disease can be included in the group after the aortic artery is opened
• Patients who are willing to participate in this study and sign informed consent
• For severely infected R6 patients, if the infection is effectively controlled, they can be considered for inclusion

Exclusion Criteria:

• Patients who refuse to participate in this observational study
• Femoral popliteal artery disease with acute and subacute thrombosis
• Patients with thromboangiitis
• Patients who have failed endovascular treatment and transferred to surgical treatment
• For patients who have received plaque exfoliation on the femoral artery
• Patients who are allergic to heparin, low molecular weight heparin and contrast agents
• Patients enrolled in other clinical studies in the past 3 months
• Pregnant women
• Patients who have a life span of less than 2 years due to serious diseases