Omega Tots Långtidsuppföljning

Experimentell: Dokosahexaensyra + Arakidonsyra

Dokosahexaensyra + Arakidonsyra (DHA+AA)

Läkemedel: Dokosahexaensyra + Arakidonsyra (DHA+AA)

200 mg DHA+ 200 mg AA per dag i 6 månader

Placebo-jämförare: Placebo

Majsolja tillskott

Kosttillskott: Placebo

400 mg majsolja per dag i 6 månader

General Cognitive Ability Score(Differential Ability Scales, Second Edition-DAS-II)

Differential Ability Scales-II General Conceptual Ability Assessment är ett mått på allmän kognitiv förmåga och används för att bedöma och identifiera barns kognitiva styrkor och svagheter. Den allmänna kognitiva förmågaspoängen har ett intervall från 30 till 170 (medelvärde=100; SD=15). Ett lågt betyg indikerar dålig prestation och ett högt betyg indikerar bästa prestation.

Executive Function (NIH Toolbox)

NIH Toolbox Cognition Battery är en multidimensionell uppsättning korta mått som bedömer kognitiv funktion. Deltesterna Flanker, Dimensional Card Sorter och Pattern Comparison mäter exekutiva funktioner, bearbetningshastighet och uppmärksamhet. Standardpoäng har ett intervall från 30 till 170 (medelvärde=100; SD=15). Ett lågt betyg indikerar dålig prestation och ett högt betyg indikerar bästa prestation.

Core Language Score (Clinical Evaluation of Language Fundamentals, Fifth Edition-CELF-5)

Clinical evaluation of Language Fundamentals, 5th edition core tests is a comprehensive measure of language and can assess children's written and oral language skills, as well as their reading comprehension. The core language score has a range from 30 to 170 (mean=100; SD=15). A low score indicates poor performance, and a high score indicates best performance.

Räfstad Pegboard uppgift

Uppgiften Grooved Pegboard mäter öga-hand-koordination och motorhastighet genom att kräva att barn sätter in pinnar i en bräda. Poängen är tiden för att placera pinnarna. Om barnet når tidsgränsen på 3 minuter, är poängen antalet utplacerade pinnar. En snabbare tid och lägre antal tappade pinnar tyder på bättre prestanda.

Antropometri-Adiposity

För att bedöma barns fetthalt används en bioelektrisk impedans för att mäta kroppsfettprocent. Barnets längd och vikt kommer att kombineras för att rapportera BMI (kg/m^2). Dessa mätningar omvandlas till ett z-poäng för ålder och kön baserat på Child Growth Standards från Världshälsoorganisationen. Z-poängen indikerar antalet standardavvikelser från medelvärdet. En z-poäng på 0 är lika med medelvärdet av en referenspopulation (barn av samma ålder och kön). Värden mindre än 0 indikerar värden som är lägre än referenspopulationen, medan värden större än 0 indikerar värden högre än referenspopulationen.

NIH Toolbox Friendship Fixed Form

NIH Toolbox Friendship (Ages 8-17) Fixed Form är ett frågeformulär med fem artiklar som mäter kamratrelationer och bedömer kvaliteten på relationer med vänner och andra bekanta under den senaste månaden. Poäng kommer att uttryckas som ett t-poäng (intervall= [16-68]; medelvärde=50; SD=10), där en högre poäng indikerar starkare kamratrelationer.

NIH Toolbox Positiv Peer Interaction Parent Report fast form

NIH Toolbox Positive Peer Interaction Form (Åldrarna 3-12) är ett frågeformulär med fyra artiklar som mäter barns kamratrelationer via föräldrarapport. Poäng kommer att uttryckas som ett t-poäng (intervall= [-8-63] ; medelvärde=50; SD=10), där en högre poäng indikerar starkare kamratrelationer.

Select Subtest From the Wechsler Intelligence Scales for Children, Fifth Edition (WISC-V)

The Weschler Intelligence Scales for Children-V Digit Span and Picture Span subtests assess working memory. The working memory index composite score has a range from 30-170 (mean=100; SD=15). A low score indicates poor performance, and a high score indicates best performance.

Select Subtests From the Kaufman Test of Educational Achievement, Third Edition (KTEA-3)

The Kaufman Test of Educational Achievement-3 is an assessment of key academic skills. The Letter and Word Recognition, Math Computation, Object Naming Facility, and Associative Fluency Subtests measure children's reading, math, and written language skills. The standard score has a range from 30-170 (mean=100; SD=15). A low score indicates poor performance, and a high score indicates best performance.

Anthropometrics-Body Composition (Height)

To assess children's body composition, height (in centimeters) is measured. This is converted to a z score for age and sex based on Child Growth Standards from the World Health Organization. The z score indicates the number of standard deviations away from the mean. A z score of 0 is equal to the mean of a reference population (children the same age and sex). Values less than 0 indicate values lower than the reference population, while values greater than 0 indicate values higher than the reference population.

Anthropometrics-Body Composition (Weight)

To assess children's body composition, weight (in kilograms) is measured. This is converted to a z score for age and sex based on Child Growth Standards from the World Health Organization. The z score indicates the number of standard deviations away from the mean. A z score of 0 is equal to the mean of a reference population (children the same age and sex). Values less than 0 indicate values lower than the reference population, while values greater than 0 indicate values higher than the reference population.

Behavior Rating Inventory of Executive Function, 2nd Edition (BRIEF-2)

The Behavior Rating Inventory of Executive Function, 2nd ed., is completed by the child's caregiver and teacher to measure a range of executive functioning capabilities in children. The BRIEF-2 yields nine clinical scales that measure various aspects of executive function plus three broad indices: behavioral regulation, emotion regulation, and cognitive regulation. Scores are summed to obtain a Global Executive Composite Score that will be expressed as a t score (range= [35-90]; (mean=50; SD=10), where a higher score indicates greater dysregulation .

Select Subscales From the Teacher Report Form 6-18

The Teacher Report Form (syndrome and DSM-Oriented subscales) is completed by the child's teacher to reflect on the child's behavior in the previous six months. Scores are summed to provide a total problems score. Scores are also computed to measure the following subscales: internalizing problems, externalizing problems, anxious/depressed, withdrawn/depressed, somatic complaints, social problems, thought problems, attention problems, rule-breaking behavior, aggression behavior, affective problems, anxiety problems, somatic problems, attention deficit/hyperactivity problems, oppositional defiant problems, conduct problems. Scores will be expressed as a t-score (range= [33-100]; mean=50; SD=10), where a lower score indicates a more optimal outcome.

Child Behavior Checklist 6-18 (CBCL) - Competence

The Child Behavior Checklist is completed by the child' caregiver to reflect their child's behavior in the previous six months. Scores were summed to provide total competence score. Total competence scores will be expressed as a t-score (range= [20-100]; mean=50; SD=10), where a higher score reflects a more optimal outcome.

National Survey of Children's Health Module - Learning Disability

The National Survey of Children's Health module captures child developmental and behavioral diagnoses and other major diagnoses via parent report . A binary variable will be formed to indicate if a child has been diagnosed with each condition or not (yes, no).

Emotion Regulation Checklist - Emotion Regulation

The Emotion Regulation Checklist is completed by the child's caregiver to measure child's ability to manage their emotions. Scores are grouped and summed to yield Emotion Regulation scale (range=10-40). Higher scores on the Emotion Regulation scale indicates more ability to regulate

Child Sleep Habits Questionnaire-abbreviated Measure

The Child Sleep Habits Questionnaire-abbreviated measures child sleep pattern and behaviors via parent report. Parents are asked to report on the child's bedtime behavior, sleep duration, and behavior during sleep. Scores are summed to give the total sleep disturbance score (range 33-99). Scores are also grouped and summed to yield eight subscales that measure different aspects of sleep. A higher score is indicative of more sleep problems .

Child Behavior Checklist 6-18 (CBCL) - Problems

The Child Behavior Checklist is completed by the child' caregiver to reflect their child's behavior in the previous six months. Scores were summed to provide problem scores. T Problem scores will be expressed as a t-score (range= [25,100]; mean=50; SD=10), where a lower score reflects a more optimal outcome.

National Survey of Children's Health Module - Developmental Delay

The National Survey of Children's Health module captures child developmental and behavioral diagnoses and other major diagnoses via parent report . A binary variable will be formed to indicate if a child has been diagnosed with each condition or not (yes, no).

National Survey of Children's Health Module - INtellectual Disability

The National Survey of Children's Health module captures child developmental and behavioral diagnoses and other major diagnoses via parent report . A binary variable will be formed to indicate if a child has been diagnosed with each condition or not (yes, no).

National Survey of Children's Health Module - Speech or Other Language Disorder

The National Survey of Children's Health module captures child developmental and behavioral diagnoses and other major diagnoses via parent report . A binary variable will be formed to indicate if a child has been diagnosed with each condition or not (yes, no).

National Survey of Children's Health Module - Behavioral or Conduct Problems

The National Survey of Children's Health module captures child developmental and behavioral diagnoses and other major diagnoses via parent report . A binary variable will be formed to indicate if a child has been diagnosed with each condition or not (yes, no).

Emotion Regulation Checklist - Lability/Negativity

The Emotion Regulation Checklist is completed by the child's caregiver to measure child's ability to manage their emotions. Scores are grouped and summed to yield a Lability/Negativity (range=14-56) scale. Higher scores on the Lability/Negativity scale reflect greater dysregulation .