Retraining Attention to Treat Alcohol Dependence and Social Anxiety (AMP)
2016年12月15日 更新者：Joshua Magee、University of Cincinnati
Cognitive Bias Modification: A Novel Intervention for Alcohol Dependence and Social Anxiety
The purpose of this research is to test a computerized intervention for people with co-occurring social anxiety and alcohol dependence.
The intervention seeks to reduce symptoms by shifting attention away from alcohol-relevant and/or socially threatening cues.
The investigators expect that participants receiving alcohol or anxiety training will experience reductions in those specific symptoms compared to participants in a control condition.
The investigators also expect that participants receiving combined alcohol and anxiety training will show the largest reductions in alcohol and anxiety symptoms, relative to participants in any other condition.
研究概览
地位
完全的
详细说明
Alcohol Use Disorders (AUDs) and Social Anxiety Disorder are disabling and chronic conditions.
In spite of these common and significantly overlapping problems, insight into the mechanisms linking alcohol dependence and social anxiety symptoms is minimal, and there are not well established treatment guidelines for this population.
In this study, the investigators seek to develop a computerized intervention for individuals with symptoms of social anxiety and alcohol dependence.
The intervention attempts to reduce symptoms by shifting attention away from alcohol-relevant and/or socially threatening cues.
The investigators expect that participants receiving alcohol or anxiety training will experience reductions in those specific symptoms compared to participants in a control condition.
The investigators also expect that participants receiving combined alcohol and anxiety training will show the largest reductions in alcohol and anxiety symptoms, relative to participants in any other condition.
研究类型
介入性
注册 (实际的)
115
阶段
- 不适用
联系人和位置
本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。
学习地点
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Ohio
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Cincinnati、Ohio、美国、45206
- University of Cincinnati Department of Family and Community Medicine
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参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
18年 及以上 (成人、年长者)
接受健康志愿者
不
有资格学习的性别
全部
描述
Inclusion Criteria:
- Current alcohol dependence
- Elevated social anxiety symptoms
- Willingness to consider cutting down on drinking
Exclusion Criteria:
- Current psychosis
- Unmanaged manic symptoms
- Significant cognitive impairment
- Other drug use in past month
- Receiving cognitive behavioral therapy for alcohol use disorder or social anxiety
- Unable to read
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
- 主要用途：治疗
- 分配：随机化
- 介入模型：并行分配
- 屏蔽：双倍的
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
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实验性的：Anxiety Attention Training only
Participants will receive Anxiety Attention Training and placebo Alcohol training.
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Anxiety Attention Training will preferentially direct participants' attention away from reminders of anxiety.
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实验性的：Alcohol Attention Training only
Participants will receive Alcohol Attention Training and placebo Anxiety training.
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Alcohol Attention Training will preferentially direct participants' attention away from reminders of alcohol.
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实验性的：Anxiety + Alcohol Attention Training
Participants will receive both Anxiety Attention Training and Alcohol Attention Training.
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Anxiety Attention Training will preferentially direct participants' attention away from reminders of anxiety.
Alcohol Attention Training will preferentially direct participants' attention away from reminders of alcohol.
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安慰剂比较：Control Training
Participants will receive placebo Anxiety Training and placebo Alcohol training.
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Placebo Anxiety Training and Placebo Alcohol Training will not preferentially direct participants' attention away from reminders of anxiety or alcohol.
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Liebowitz Social Anxiety Scale
大体时间：Baseline, weekly throughout the 4-week trial, and in the follow-up sessions (1 week and 1 month follow-ups)
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The experimenter-administered Liebowitz Social Anxiety Scale (Liebowitz, 1987) was the primary measure to assess social anxiety symptoms.
This well-validated instrument assesses fear and avoidance across a range of 24 social and performance situations during the course of the previous week.
A total LSAS score was computed, ranging from 0 (no fear or avoidance) to 144 (the greatest level of fear and avoidance).
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Baseline, weekly throughout the 4-week trial, and in the follow-up sessions (1 week and 1 month follow-ups)
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The Daily Drinking Questionnaire
大体时间：Baseline, weekly throughout the 4-week trial, and in the follow-up sessions (1 week and 1 month follow-ups)
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The Daily Drinking Questionnaire (Collins, Parks, & Marlatt, 1985) was the primary measure used to assess weekly alcohol consumption.
This calendar-based measure was administered by the experimenter once per week to monitor changes in symptoms.
The measure assessed the total number of drinks in the past week.
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Baseline, weekly throughout the 4-week trial, and in the follow-up sessions (1 week and 1 month follow-ups)
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合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
调查人员
- 首席研究员：Joshua C Magee, Ph.D.、University of Cincinnati
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始
2013年7月1日
初级完成 (实际的)
2014年12月1日
研究完成 (实际的)
2014年12月1日
研究注册日期
首次提交
2013年6月17日
首先提交符合 QC 标准的
2013年6月21日
首次发布 (估计)
2013年6月26日
研究记录更新
最后更新发布 (估计)
2016年12月28日
上次提交的符合 QC 标准的更新
2016年12月15日
最后验证
2016年12月1日
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.
Anxiety Attention Training的临床试验
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Karolinska InstitutetMinistry of Health and Social Affairs, Sweden完全的
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Mental Health Services in the Capital Region, DenmarkCopenhagen Trial Unit, Center for Clinical Intervention Research; Center for Clinical Intervention...完全的
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Rush University Medical CenterNational Center for Complementary and Integrative Health (NCCIH)完全的