Impact of Guidelines on Cardiovascular and Economic Outcomes With Focus on Lipid Lowering Drugs (GuLLD)
Predicted Impact on Cardiovascular and Economic Outcomes of Swedish Atherosclerotic Cardiovascular Disease Guideline 2014 With Focus on Lipid Lowering Treatment
研究概览
详细说明
SWEDEHEART is a Swedish national registry consisting of several sub registries in which patients with acute coronary syndrome are prospectively registered. Patient characteristics, hospital treatments, drug treatments at discharge, and outcome for patients consecutively included and treated at all Swedish coronary care units are collected in this registry.SEPHIA is a sub registry collecting data on secondary prevention and cardiac rehabilitation. Follow-up are registered at six to ten weeks and at 12 to14 months post MI by office visits or phone. Around 80 % of all Swedish acute myocardial infarction (AMI) patients below the age of 75 years are included in this register.
In this study, a cohort of 5 904 (74% men) registered in the SEPHIA registry and who had one year follow-up during 2013, will be included. Data are aggregated and delivered from the SWEDEHEART/SEPHIA national registry. All patients were informed about their participation in the registry, the follow-up, and their right to decline participation. No written consent was obtained
研究类型
注册 (实际的)
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria: All patients with acute myocardial infarction registered in the SEPHIA registry and who had one year follow-up during 2013 -
Exclusion Criteria:none
-
学习计划
研究是如何设计的？
设计细节
队列和干预
团体/队列 |
干预/治疗 |
|---|---|
|
Well-controlled cohort (LDL-C ≤ 1.8 mmol/L)
Individuals in the Swedish Secondary Prevention after Heart intensive care Admission (SEPHIA) is a sub register within SWEDEHEART collecting data on secondary prevention and cardiac rehabilitation with well-controlled LDL-cholesterol
|
Both groups got treatment but well-controlled reached target of LDL-C<1.8 mmol/l
其他名称：
|
|
Non-controlled cohort
Individuals in the Swedish Secondary Prevention after Heart intensive care Admission (SEPHIA) is a sub register within SWEDEHEART collecting data on secondary prevention and cardiac rehabilitation and with not well-controlled LDL-C
|
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Percentage of AMI patients who have achieved target goal of LDL-cholesterol 1.8 mmol/L or not
大体时间：AMI patients with one year follow-up year 2013
|
Treatment gap will be analysed in well-controlled (LDL-C ≤1.8 mmol/L) and non-controlled ( LDL-C >1.8 mmol/L) cohort in men and women separately.
|
AMI patients with one year follow-up year 2013
|
次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Number of predicted CVD events gained if target LDL-cholesterol was achieved in the non-controlled group
大体时间：Predicted number of events within a 10 year period
|
Number of events predicted to occur in the non-controlled group
|
Predicted number of events within a 10 year period
|
|
Health care costs in SEK saved, due to number of predicted CVD events gained if target LDL-cholesterol was achieved in the non-controlled group
大体时间：Predicted health care costs within a 10 year period
|
Health care costs predicted to be gained if the non-controlled group achieved target LDL-cholesterol
|
Predicted health care costs within a 10 year period
|
合作者和调查者
调查人员
- 首席研究员：Gunilla Journath, PhD、Karolinska Institutet
出版物和有用的链接
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.
Well-controlled的临床试验
-
Geisinger ClinicPatient-Centered Outcomes Research Institute; Penn State University; University of Nebraska; Iowa...主动，不招人
-
University of PittsburghNational Institute of Mental Health (NIMH)招聘中
-
Washington University School of MedicineNational Institute on Drug Abuse (NIDA)完全的性病 | 艾滋病病毒 | 药物滥用
-
Chelsea and Westminster NHS Foundation TrustImperial College London; University of Westminster完全的
-
University of California, Los AngelesEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); Health...完全的
-
University of LiverpoolSt Helens & Knowsley Teaching Hospitals NHS Trust尚未招聘