Group Therapy for Postpartum Depression

January 23, 2014 updated by: University of Wisconsin, Madison

Relational Group Intervention for Postpartum Depression

This study will compare standard individual treatment to group therapy for the treatment of postpartum depression.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Ten to twenty percent of new mothers experience major depression in the postpartum period or postpartum depression (PPD). This condition poses a risk for disturbances in the mother-infant relationship as well as for developmental delays and subsequent psychopathology in their children. Thus, and investigation of the efficacy of a relational approach that focuses on improving the mother's sense of competence in the parenting role, and reducing depressive symptoms and social isolation through group therapy is warranted.

Patients are randomly assigned to either relational group treatment or to standard individual treatment. Assessments of maternal and infant functioning, mother-infant and father-infant relations, parenting stress, and marital conflict and conducted pre- and post-treatment, at 12 months post-treatment, and when infants are 12 and 24 months of age.

Study Type

Interventional

Enrollment (Actual)

147

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • Wisconsin
      • Madison, Wisconsin, United States, 53719
        • University of Wisconsin Dept. of Psychiatry

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

Female

Description

Inclusion Criteria:

  • Major depression with an infant under 7 months of age

Exclusion Criteria:

  • Bipolar disorder
  • Schizophrenia
  • Organic brain syndrome
  • Antisocial personality disorder
  • Current psychosis or mania
  • Lifetime history of mental retardation
  • Current alcohol or substance abuse
  • Cognitive disability
  • Infants born more than 6 weeks premature or with major medical conditions or developmental disabilities

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: 1 M-ITG
Mother-infant group psychotherapy
Behavioral: Mother-Infant Group Psychotherapy
Mother-infant group psychotherapy consists of weekly 2.5-hour psychotherapy sessions comprised of mother's group therapy, infant developmental therapy, and mother-infant dyadic psychotherapy. Group treatment will last 15 weeks.
Active Comparator: 2 - IPT
Individual interpersonal psychotherapy
Behavioral: Interpersonal Psychotherapy
Individual psychotherapy treatment focuses on role transition, interpersonal relationships, and loss. Individual treatment period will last 15 weeks.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Reduction of depression as measured by the Hamilton Rating Scale for Depression (HRSD)
Time Frame: Measured at post-treatment and Month 12 follow-up
Measured at post-treatment and Month 12 follow-up

Secondary Outcome Measures

Outcome Measure
Time Frame
Improvement in parent-infant interactions as measured by the Early Relational Assessment (ERA)
Time Frame: Measured at post-treatment, Month 12 follow-up, and 12 and 24 months of age
Measured at post-treatment, Month 12 follow-up, and 12 and 24 months of age

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Wisconsin, Madison

Collaborators

National Institute of Mental Health (NIMH)

Investigators

  • Principal Investigator: Roseanne Clark, PhD, University of Wisconsin, Madison

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

January 1, 2002

Primary Completion (Actual)

July 1, 2008

Study Completion (Actual)

July 1, 2008

Study Registration Dates

First Submitted

January 7, 2003

First Submitted That Met QC Criteria

January 7, 2003

First Posted (Estimate)

January 8, 2003

Study Record Updates

Last Update Posted (Estimate)

January 24, 2014

Last Update Submitted That Met QC Criteria

January 23, 2014

Last Verified

January 1, 2014

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • R01MH062054 (U.S. NIH Grant/Contract)

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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