Comparison of Four Different Aberrometers for Evaluation of Higher Order Visual Aberrations

An aberrometer measures visual aberrations by mapping how light rays travel through the eye and by providing maps using colored gradients to represent the magnitude of refractive errors of the eye.

The purpose of this study is to compare 4 different aberrometers -Wavescan (Visx Technology), Zywave (Bausch & Lomb), Ladarwave aberrometer (Alcon Inc.) and Allegro Analyzer (Alcon Inc). In particular, the investigators propose to focus on the ability of these devices to display the higher order visual aberrations and to compare the quality of outputs from these 4 devices in normal healthy subjects.

Study Overview

• Status: Completed
• Conditions: Normal Individuals With Visual Aberrations

• Study Type: Observational
• Enrollment (Actual): 21

Contacts and Locations

Study Locations

• United States
  • Massachusetts
    • Boston, Massachusetts, United States, 02114
      • Massachusetts Eye and Ear Infirmary

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Normal subjects over the age of 18 with visual abberations.

Description

Inclusion Criteria:

• male or female, at least 18 years of age
• no ocular abnormality other than refractive error
• patient in generally good & stable overall health
• has not worn contact lenses (hard or gas permeable lenses for at least 3 weeks and soft lenses for at least 3 days) prior to the study exam
• corneal topography must be normal, as judged by the investigator
• topical anesthesia and mydriatics must be tolerated
• patient must be able to fixate steadily
• ability to understand and provide informed consent to participate in this study

Exclusion Criteria:

• history of ocular surgery
• history of ocular trauma, infection, disease, or abnormality other than refractive error
• myopia or hyperopia > 7.0 D, astigmatism >3.0 D
• uncorrectable visual acuity below 20/20
• abnormal corneal topography pattern including, but not limited to keratoconus, forme fruste keratoconus, or corneal warpage
• pupil sizes below 6.0 mm under mydriasis
• iris problems including, but not limited to, coloboma and previous iris surgery
• ocular media problems, corneal, lens and/or vitreous opacities including, but not limited to cataract
• ocular movement abnormalities including, but not limited to, strabismus or nystagmus
• phenol red thread test (Zone Quick-Menicon Ltd) less than 9 mm/15 seconds
• pregnancy and lactation

Study Plan

How is the study designed?

Design Details

• Time Perspectives: Prospective

Collaborators and Investigators

• Sponsor: Massachusetts Eye and Ear Infirmary
• Investigators: Principal Investigator: Roberto Pineda, MD, Massachusetts Eye and Ear Infirmary

Study record dates

Study Major Dates

• Study Start: August 1, 2010
• Primary Completion (Actual): July 1, 2011
• Study Completion (Actual): July 1, 2011

Study Registration Dates

• First Submitted: October 27, 2010
• First Submitted That Met QC Criteria: October 27, 2010
• First Posted (Estimate): October 28, 2010

Study Record Updates

• Last Update Posted (Estimate): December 21, 2011
• Last Update Submitted That Met QC Criteria: December 19, 2011
• Last Verified: December 1, 2011

More Information

Terms related to this study

• Other Study ID Numbers: 09-03-016