Disability and Self-rated Health Following Primary Knee Replacement

October 17, 2023 updated by: Esa Jamsen, Coxa, Hospital for Joint Replacement

The Effects of Primary Knee Replacement for Osteoarthritis on Disability in Activities of Daily Living and Self-rated Health in Older People

Knee replacement is an effective treatment in late-stage osteoarthritis. It reduces pain and improves quality of life. There is, however, limited data concerning its results in older people and on its effect on how patients survive in regular activities of daily living (ADL), such as bathing and shopping. In this study, the results of knee replacement are evaluated from the point of view of disability in everyday activities and self-rated health. Moreover, association with ADL performance and clinical knee scores and severity of osteoarthritis are assessed.

Study Overview

Status

Completed

Conditions

Detailed Description

This is a cross-sectional study with a 12 month follow-up for recruited patients. Most data are gathered by a postal questionnaire.

Study Type

Observational

Enrollment (Actual)

460

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Finland
      • Tampere, Finland, 33101
        • Coxa, Hospital for Joint Replacement

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

75 years and older (Older Adult)

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

Patients refererred to or operated on with primary knee replacement in a population-based tertiary care hospital

Description

Inclusion Criteria:

  • age 75 years or more at the time of operation
  • diagnosis of knee osteoarthritis
  • scheduled for or operated on with primary knee replacement

Exclusion Criteria:

  • died during the follow-up
  • inflammatory arthritides

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Knee replacement recipients
Patients (aged 75 years or over) with late-stage arthritis who have undergone or are undergoing primary knee replacement

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Disability in activities of daily living
Time Frame: Baseline (recruitment) and at 12 months
Baseline (recruitment) and at 12 months

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Overall self-rated health
Time Frame: Baseline (recruitment) and at 12 months
Baseline (recruitment) and at 12 months
Health-related quality of life (WOMAC)
Time Frame: Baseline and 12 months postoperatively
For patients recruited in 2011-2012.
Baseline and 12 months postoperatively

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Coxa, Hospital for Joint Replacement

Collaborators

Tampere University

Investigators

  • Study Director: Esa Jämsen, MD, PhD, Coxa, Hospital for Joint Replacement

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

December 1, 2009

Primary Completion (Actual)

November 30, 2013

Study Completion (Actual)

December 31, 2015

Study Registration Dates

First Submitted

December 22, 2009

First Submitted That Met QC Criteria

November 8, 2010

First Posted (Estimated)

November 9, 2010

Study Record Updates

Last Update Posted (Actual)

October 18, 2023

Last Update Submitted That Met QC Criteria

October 17, 2023

Last Verified

October 1, 2023

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • KL122009

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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