Psychometric Studies of the Chinese Versions of the SRS, CAST, and AQ

Psychometric Studies of the Chinese Versions of the Social Responsiveness Scale, the Childhood Asperger's Syndrome Test, and the Autism Spectrum Quotient

Autism spectrum disorder (ASD) is a pervasive neurodevelopmental disorder with prominent reciprocal social and communication impairment and restricted repetitive behavior or interest. ASD is a highly heritable disease with tremendous impact on individuals, families, and society. In addition to the interview instruments, self-administered rating scales are commonly used in screening, assessment of symptoms' change, and evaluation of intervention effects. The Social Responsiveness Scale, the Childhood Asperger's Syndrome Test, and the Autism Spectrum Quotient are internationally widely used rating scales measuring autistic traits in both clinical and community samples in western counties. Establishment of internationally-recognized reliable and valid instruments is not only useful for clinical screening, but also helpful in future functional outcomes, neurocognitive, genetic and brain imaging studies.

Study Overview

• Status: Completed
• Conditions: Autism Spectrum Disorder

Detailed Description

Specific Aims:

1. To identify the factor structures and norms of the SRS, CAST, and AQ;
2. To assess the concurrent validity of the SRS, CAST, and AQ;
3. To assess the discriminative validity of the three scales by testing the difference of total scores and subscales scores of the SRS, CAST, and AQ between the ASD, attention-deficit hyperactivity disorder (ADHD), and control groups;
4. To correlate the autistic characteristics between parents and children and compare the magnitude of correlations of autistic traits across the 3 groups.

This is a cross-sectional questionnaire survey in school-based and clinic-based samples. The participants include (1) ASD group: 200 cases with DSM-IV ASD; (2) ADHD group: 200 cases with DSM-IV ADHD; (3) Normally developing control group: a school-based sample of around 1200 grade 1 to grade 8 students. 100 students randomly selected from school-based sample will be reassessed at a 2-week interval for the test-retest reliability study. The teachers will complete the SRS and SNAP-IV (for ADHD symptoms); parents will report on their children on the SCQ, SRS, CAST, SNAP-IV, and CBCL, and report themselves on the SRS, AQ, and ASRI; children will report on themselves using the SRS, AQ, SNAP-IV, and YSR. Parents of clinical participants will be interviewed by the ADI-R or K-SADS-E to confirm their diagnosis of ASD and ADHD, respectively.

We expect that this study will reach the following objectives:

1. To establish psychometric properties of the Chinese versions of SRS, CAST, and AQ for future use in clinical, school, and research settings;
2. To obtain the preliminary information about the prevalence of ASD, and understand the correlation of autistic traits in family;
3. To enhance the awareness of school teachers and counselors about ASD among students.

• Study Type: Observational
• Enrollment (Actual): 2460

Contacts and Locations

Study Locations

• Taiwan
  • Taipei, Taiwan
    • National Taiwan Univeristy Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 6 years to 16 years (Child)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

The participants include (1) ASD group: 200 cases with DSM-IV ASD; (2) ADHD group: 200 cases with DSM-IV ADHD; (3) Normally developing control group: a school-based sample of around 1200 grade 1 to grade 8 students.

Description

Inclusion Criteria:

• Control group: Subjects without ADHD or ASD;
• ADHD group & ASD group: subjects have a clinical diagnosis of ADHD, or ASD defined by the Diagnostic and Statistical Manual, Fourth Edition (DSM-IV), which was made by a full-time board-certificated child psychiatrist at the first visit and following visits.

Exclusion Criteria:

• The subjects will be excluded from the study if they currently meet criteria or have a history of the following condition as defined by DSM-IV: Schizophrenia, Schizoaffective Disorder, Organic Psychosis, Mental Retardation, or Pervasive Developmental Disorder. Moreover, the subjects will be excluded from the control group if have a history of the following condition as defined by DSM-IV: ADHD or ASD in addition to the above exclusion criteria.

Study Plan

How is the study designed?

Number of groups / cohorts

3

Cohorts and Interventions

Group / Cohort
ASD group
ADHD group
Normally developing control group

Collaborators and Investigators

• Sponsor: National Taiwan University Hospital

Study record dates

Study Major Dates

• Study Start: January 1, 2011
• Study Completion (Actual): December 1, 2011

Study Registration Dates

• First Submitted: November 22, 2010
• First Submitted That Met QC Criteria: November 23, 2010
• First Posted (Estimate): November 24, 2010

Study Record Updates

• Last Update Posted (Estimate): November 15, 2012
• Last Update Submitted That Met QC Criteria: November 14, 2012
• Last Verified: April 1, 2012

More Information

Terms related to this study

• Keywords: Autism spectrum disorder; psychometric; Social Responsiveness Scale; Childhood Asperger's Syndrome Test; Adult Autism Spectrum Quotient
• Additional Relevant MeSH Terms: Mental Disorders; Neurodevelopmental Disorders; Child Development Disorders, Pervasive; Autistic Disorder; Autism Spectrum Disorder; Asperger Syndrome
• Other Study ID Numbers: 201005041R