DaHuang GangTsao Tang to Improve the Appetite Loss Condition of Cancer Patients (TCM)
February 13, 2020 updated by: Changhua Christian Hospital
Taking Herbal Formula：DaHuang GangTsao Tang to Improve the Appetite Loss Condition of Cancer Patients in Late-stage：A Clinical Control Trial Study
Appetite loss is a severe and common symptom among late-stage cancer patients, and it causes great the anxiety for the patient's family.
In TCM theory, the investigators call these patients are in block and repulsion condition.
The investigators try to set a study to use the herbal medicine solution taken in frequent small amounts by cancer patients in late-stage to improve the appetite loss condition.
Through this method, the investigators not only want to improve the quality of life of cancer patients in late-stage but also set a valuable treatment.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
Intervention group
- 1. 2 grams of DaHuang abstract powder and 0.5 grams GanTsao abstract powder are mixed and separated into four packages;
- 2. each package was given to each patient four times a day (three time after meal and one time before sleep);
- 3. each patient received the usual medication of the hospice ward at the same time;
- 4. record the patients' score of pre-test, mid-test and after-test of QIPCTP at the 1st day, the 3rd day and the 6th day;
- 5. record the patients' score of EORTC QLQ-C30 V3.0 and ECOG (Eastern Cooperative Oncology Group Performance Status) at the 1st day and the 6th day.
Control group
- 1. each patient received the usual medication of the hospice ward during the trial interval;
- 2. record the patients' score of receive pre-test, mid-test and after-test of QIPCTP at the 1st day, the 3rd day and the 6th day;
- 3. record the patients' score of EORTC QLQ-C30 V3.0 and ECOG (Eastern Cooperative Oncology Group Performance Status) at at the 1st day and the 6th day.
Medicine DaHuang herbal abstract powder is produced by Sun Ten Pharmaceutical Co., Ltd, and it's product serial number: 276001. GanCao herbal abstract powder is also produced by Sun Ten Pharmaceutical Co., Ltd, and it's product serial number: 185645. Each herbal abstract powder is qualified with the data of HPLC to confirm each content and stability. The pharmaceutical company is qualified by Good Manufacturing Practice (GMP) certification in Taiwan.
Study Type
Interventional
Enrollment (Actual)
4
Phase
- Phase 2
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Changhua Country
-
Changhua City, Changhua Country, Taiwan, 500
- Changhua Christan Hospital
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
20 years to 80 years (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
- Terminal cancer patients in hospice ward
- Patients with appetite loss condition
- Ages between 20 to 80 years old
- No history of diabetes
Exclusion Criteria:
- Entered the stage of dying patients
- Receiving other traditional Chinese medicine
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Supportive Care
- Allocation: N/A
- Interventional Model: Single Group Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: herbal medicine
Intervention group
|
Intervention group
Other Names:
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
appetite score
Time Frame: 6 days
|
The investigators detect the patients' appetite condition at the 1st,3rd and 6th day.
|
6 days
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Study Chair: Yu De LIU, Master, Changhua Christian Hospital
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
March 1, 2011
Primary Completion (Actual)
September 1, 2011
Study Completion (Actual)
March 1, 2013
Study Registration Dates
First Submitted
November 7, 2011
First Submitted That Met QC Criteria
January 3, 2012
First Posted (Estimate)
January 4, 2012
Study Record Updates
Last Update Posted (Actual)
February 17, 2020
Last Update Submitted That Met QC Criteria
February 13, 2020
Last Verified
February 1, 2020
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- 100610
- Protocol Record 100610 (Registry Identifier: YDLiu)
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.